Results 111 to 120 of about 526,165 (306)

Application of Neurospora crassa in the Treatment of Waste [PDF]

open access: yes, 2014
The nutrient requirements of the fast growing filamentous fungi Neurospora crassa to convert animal waste into an edible product containing high amounts of protein were assessed by selectively excluding nutrients from supplemental solutions of Vogel ...
Przybyla, Matthew, Wunderlich, John
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Phytogenic and prebiotic feed additives as antibiotic substitutes: effects on broiler meat quality, organ properties, and production efficiency when fed standard and reduced energy and protein diets

open access: yesCogent Food & Agriculture
This study investigated the impact of reduced dietary metabolizable energy (ME) and crude protein (CP) levels on broiler breast meat quality, internal organ yields, feed efficiency (FE), and the European production efficiency factor (EPEF), with or ...
Maged A. Al-Garadi   +7 more
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

NY Pollution Discharge Elimination Permits for CAFOs, Management Adjustments and the Environment [PDF]

open access: yes
Weakening demand for livestock and dairy produce, historically high prices for feed ingredients and increasingly strict regulations on animal waste management continue to put significant pressure on livestock and dairy operating margins.
Boisvert, Richard N.   +2 more
core   +1 more source

Evaluation criteria for including feed materials in Annex II C and dietary supplements in Annex II D of the EC-Regulation 2092/91 [PDF]

open access: yes, 2006
Organic livestock farming is intended to contribute to the equilibrium of agricultural production systems; establish and maintaining an interdependence between soils, plants and animals; is land-related ruling out landless productions, and should support
Padel, S., Sundrum, A.
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

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