Results 141 to 150 of about 520,936 (312)

Review of best management practices for aquatic vegetation control in stormwater ponds, wetlands, and lakes [PDF]

open access: yes, 2013
Auckland Council (AC) is responsible for the development and operation of a stormwater network across the region to avert risks to citizens and the environment.
Champion, Paul   +10 more
core  

Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node

open access: yesFEBS Open Bio, EarlyView.
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner   +6 more
wiley   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

open access: yesFEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan   +6 more
wiley   +1 more source

Calcium‐sensing receptor induces the apoptosis of chondrocytes in cooperation with phosphate transporter

open access: yesFEBS Open Bio, EarlyView.
Excess Ca2+ ions activate the Calcium‐Sensing Receptor (CaSR), which subsequently drives the uptake of excess inorganic phosphate (Pi) via the Pi transporter (Pit−1) in chondrocytes. This mechanism causes a toxic increase in intracellular Pi concentration, ultimately leading to chondrocyte apoptosis and pathological mineralization. Excess extracellular
Sachie Nakatani   +7 more
wiley   +1 more source

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

open access: yesFEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito   +3 more
wiley   +1 more source

Nutrient allocations and metabolism in two collembolans with contrasting reproduction and growth strategies [PDF]

open access: yes, 2009
Physiological mechanisms such as allocation and release of nutrients are keys to understanding an animal\u27s adaptation to a particular habitat. This study investigated how two detrivores with contrasting life‐history traits allocated carbon (C) and ...
Damgaard, Christian   +4 more
core   +1 more source

Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe

open access: yesFEBS Open Bio, EarlyView.
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley   +1 more source

Nutrient Trading in the Chesapeake Bay Region: An Analysis of Supply and Demand [PDF]

open access: yes, 2010
This report provides an overview of nutrient trading programs as they currently exist in the Chesapeake Bay watershed and examines the potential for supply and demand of credits within those markets.
Brian Kittler   +3 more
core  

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

open access: yesFEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso   +4 more
wiley   +1 more source

Energy and SID lysine partitioning in pigs weighing 32–196 kg, voluntarily fed diets differing in SID lysine content

open access: yesItalian Journal of Animal Science
This study investigated the partitioning of metabolisable energy (ME) and standardised ileal digestible (SID) lysine in 96 Goland-C21 × Camborough-43 pigs, raised from 32 to 196 kg of body weight (BW) and fed voluntarily diets containing low (L), medium ...
Stefano Schiavon   +10 more
doaj   +1 more source

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