Results 121 to 130 of about 2,469,745 (360)

Approximating Mexican highways with slime mould

, 2010
Plasmodium of Physarum polycephalum is a single cell visible by unaided eye. During its foraging behavior the cell spans spatially distributed sources of nutrients with a protoplasmic network. Geometrical structure of the protoplasmic networks allows the
A Adamatzky, A Adamatzky, A Adamatzky, A Adamatzky, A McClory, A Tero, Andrew Adamatzky, Christopher R. Stephens, D Watanabe, D Watanabe, DJC Knowles, DR Reyes, DW Matula, Genaro J. Martínez, GT Toussaint, I Chet, JW Jaromczyk, KR Gabriel, M Dorigo, MJ Carlile, P Santi, P-J Wan, RB Muhammad, RD Coman, René Asomoza-Palacio, RL Kincaid, S Tsuda, S Tsuda, Sergio V. Chapa-Vergara, T Nakagaki, T Nakagaki, T Ueda, TC Jarrett, X-Y Li   +33 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

LncRNA OIP5-AS1 suppresses lung adenocarcinoma progression and modulates macrophage polarization through the miR-429/DOCK4 regulatory axis

Frontiers in Pharmacology
BackgroundMacrophage polarization plays a pivotal role in shaping the tumor microenvironment and influencing cancer progression. Long non-coding RNAs (lncRNAs) have emerged as important regulators of this process.
Yihan Liu, Yuhua Wang, Long Cui, Runze Li, Dan Xiao, Dan Xiao   +5 more
doaj   +1 more source

The potential of ecological recycling agriculture (ERA) for improved nature resource conservation and reduced environmental impacts in the Baltic Sea drainage area [PDF]

, 2005
By integrating crop and animal production on a farm or farms in closed cooperation combined with soil formation legume crops in balanced crop-rotations it will be possible to maximize the efficient use of nutrients in manure, minimize inputs of limited ...
Granstedt, Artur, Schneider, Thomas, Seuri, Pentti, Thomsson, Olof   +3 more
core  

Pineapples internal quality inspection approaches and its potential effects in Malaysia [PDF]

, 2020
Pineapple (Ananas Comosus L. Metil) is a tropical plant under Bromeliaceous family that is grown in American tropics, subtropics, and warmer regions (U. Nations 2012). Pineapple is the second harvest tropical fruit after banana in the world (S.
Jam, Mohamad Nur Hakim, Kim, Seng Chia, Yit, Peng Tan   +2 more
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gabor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Neural electrodes for brain‐computer interface system: From rigid to soft

BMEMat
Brain‐computer interface (BCI) is an advanced technology that establishes a direct connection between the brain and external devices, enabling high‐speed and real‐time information exchange. In BCI systems, electrodes are key interface devices responsible
Dan Yang, Gongwei Tian, Jianhui Chen, Yan Liu, Esha Fatima, Jichuan Qiu, Nik Ahmad Nizam Nik Malek, Dianpeng Qi   +7 more
doaj   +1 more source

Nutrients in waters on the inner shelf between Cape Charles and Cape Hatteras [PDF]

The distribution of nutrients in the shelf waters of the southern tip of the Middle Atlantic Bight was investigated. It is concluded that the outflow of freshwater from the Chesapeake Bay is a potential source of nutrients to the adjacent shelf waters ...
Todd, J. F., Wong, G. T. F.
core   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source