Results 71 to 80 of about 2,370,327 (359)

Regulation of arginine transport by GCN2 eIF2 kinase is important for replication of the intracellular parasite Toxoplasma gondii [PDF]

open access: yes, 2019
Toxoplasma gondii is a prevalent protozoan parasite that can infect any nucleated cell but cannot replicate outside of its host cell. Toxoplasma is auxotrophic for several nutrients including arginine, tryptophan, and purines, which it must acquire from ...
Amin, Parth H.   +3 more
core   +2 more sources

A Review of Dietary (Phyto)Nutrients for Glutathione Support

open access: yesNutrients, 2019
Glutathione is a tripeptide that plays a pivotal role in critical physiological processes resulting in effects relevant to diverse disease pathophysiology such as maintenance of redox balance, reduction of oxidative stress, enhancement of metabolic ...
D. Minich, Benjamin I Brown
semanticscholar   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

open access: yesFEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino   +7 more
wiley   +1 more source

p53 protein degradation redefines the initiation mechanisms and drives transitional mutations in colorectal cancer

open access: yesNature Communications
Incidence of colorectal cancer (CRC) is increasing likely due to different mechanisms driving initiation and progression. The initial model proposed by Fearon and Vogelstein posits it as a multi-hit neoplasia, originating from adenomatous-polyps induced ...
Irene Herranz-Montoya   +6 more
doaj   +1 more source

Biogeochemical nutrient cycles and nutrient management strategies [PDF]

open access: yesHydrobiologia, 1999
Nutrient loading by riverine input into estuarine systems has increased by 6–50 times for the N load from pristine conditions to present, whereas a 18–180 times increase has been observed in the P load. Reductions in the ratio of N to P delivery has also occurred with time.
openaire   +2 more sources

Can Organic Sources of Nutrients Increase Crop Yields to Meet Global Food Demand?

open access: yesAgronomy, 2018
Meeting global demand of safe and healthy food for the ever-increasing population now and into the future is currently a crucial challenge. Increasing crop production by preserving environment and mitigating climate change should thus be the main goal of
J. Timsina
semanticscholar   +1 more source

ROLE OF NUTRIENTS IN WHEAT: A REVIEW

open access: yesTropical Agrobiodiversity, 2020
Wheat (Triticum aestivum L.) is an important cereal crop that provides ample nutritious calories for humans and animals. The nutrient plays a vital role in the production of wheat.
M. Pandey   +3 more
semanticscholar   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

The Role of Dietary Nutrients in Inflammatory Bowel Disease

open access: yesFrontiers in Immunology, 2019
Inflammatory bowel disease (IBD) is a chronic and relapsing inflammatory disease of the gastrointestinal tract. Although the precise etiology of IBD remains incompletely understood, accumulating evidence suggests that various environmental factors ...
Kohei Sugihara   +2 more
semanticscholar   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

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