Results 81 to 90 of about 2,469,745 (360)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Effects of Potassium Source and Secondary Nutrients on Potato Yield and Quality in Southcentral Alaska. [PDF]

, 1990
Calcium (Ca), magnesium (Mg), and sulfur (S) are required for the growth and development of all higher plants. They are commonly referred to as secondary nutrients because they are less often limiting to plant growth than the primary nutrients nitrogen ...
Gavlak, Raymond G., Muniz, June E., Walworth, James L.   +2 more
core  

Can Organic Sources of Nutrients Increase Crop Yields to Meet Global Food Demand?

Agronomy, 2018
Meeting global demand of safe and healthy food for the ever-increasing population now and into the future is currently a crucial challenge. Increasing crop production by preserving environment and mitigating climate change should thus be the main goal of
J. Timsina
semanticscholar   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source

The Role of Dietary Nutrients in Inflammatory Bowel Disease

Frontiers in Immunology, 2019
Inflammatory bowel disease (IBD) is a chronic and relapsing inflammatory disease of the gastrointestinal tract. Although the precise etiology of IBD remains incompletely understood, accumulating evidence suggests that various environmental factors ...
Kohei Sugihara, Tina L. Morhardt, N. Kamada   +2 more
semanticscholar   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Pathways for Nutrient Loss to Water; Slurry and Fertilizer Spreading [PDF]

, 2008
End of project reportThere are almost 150,000 farms in Ireland and these contribute substantial quantities of N and P to inland and coastal waters. Some of these nutrients are carried from wet soils by overland flow and by leaching from dry soils.
Carton, Owen T., Fitzgerald, D., Holden, Nicholas M., Murphy, F., Ryan, T. Declan   +4 more
core  

Morphological Instabilities in a growing Yeast Colony: Experiment and Theory [PDF]

, 1996
We study the growth of colonies of the yeast Pichia membranaefaciens on agarose film. The growth conditions are controlled in a setup where nutrients are supplied through an agarose film suspended over a solution of nutrients.
A. M. Turing, A. P. J. Trinci, Bjørn Eggert Christensen, Clive Ellegaard, D'Arcy Thompson, D. B. Patankar, E. Ben-Jacob, E. Ben-Jacob, G. I. Sivashinsky, J. A. Shapiro, J. A. Shapiro, J. A. Soddell, J. Bechhoefer, J. O. Kessler, J. S. Langer, J. W. Crawford, J. Wakita, K. J. Lee, K. Sneppen, Kim Sneppen, M. J. Carlile, M. Kertzberg, Mogens H. Jensen, N. A. Hill, R. E. Goldstein, S. Matsuura, S. Matsuura, S. Sarkar, T. Halpin-Healy, Thomas Sams, Ulf Thrane, Y. Kuramoto, Y. Kuramoto, Y. Shimada   +33 more
core   +2 more sources