Results 71 to 80 of about 3,590 (205)

Genetically-Guided Medical Nutrition Therapy in Type 2 Diabetes Mellitus and Pre-diabetes: A Series of n-of-1 Superiority Trials

open access: yesFrontiers in Nutrition, 2022
Type 2 diabetes mellitus (T2DM) is a heterogeneous metabolic disorder of multifactorial etiology that includes genetic and dietary influences. By addressing the latter, medical nutrition therapy (MNT) contributes to the management of T2DM or pre-diabetes
Kalliopi K. Gkouskou   +9 more
doaj   +1 more source

The Genetic Blueprint of Obesity: From Pathogenesis to Novel Therapies

open access: yesObesity Reviews, Volume 26, Issue 12, December 2025.
ABSTRACT Obesity is a chronic metabolic disease characterized by disturbances in energy homeostasis, leading to excessive fat accumulation. The pathogenesis of the disease is shaped by a complex interplay of genetic, epigenetic, biological, psychological, and environmental factors.
Gašper Tonin   +6 more
wiley   +1 more source

Effects of Single Nucleotide Polymorphisms and Mediterranean Diet in Overweight or Obese Postmenopausal Women With Breast Cancer Receiving Adjuvant Hormone Therapy: A Pilot Randomized Controlled Trial

open access: yesFrontiers in Nutrition, 2022
Background and AimsWeight management is recommended in overweight or obese breast cancer patients, as they have an increased risk of cancer recurrence and poor prognosis.
A-Ra Cho   +9 more
doaj   +1 more source

Genotype-based personalised nutrition for obesity prevention and treatment: are we there yet? [PDF]

open access: yes, 2016
Interactions between genotype and dietary intake include genetic moderation of the effect of dietary intake on disease development (nutrigenetics). Research on nutrigenetics has focused mainly on single-nucleotide polymorphisms (SNPs) and supports the ...
Senekal, Marjanne
core  

The good life: living for health and a life without risks? On a prominent script of nutrigenomics [PDF]

open access: yes
Like all scientific innovations, nutrigenomics develops through a constant interplay with society. Normative assumptions, embedded in the way researchers formulate strands of nutrigenomics research, affect this interplay.
Komduur, R.H.   +2 more
core   +2 more sources

Characterization of metabolically healthy obese people and metabolically unhealthy normal-weight people in a general population cohort of the ABCD Study [PDF]

open access: yes, 2017
There is actually no consensus about the possibility that in some instances, obesity may be a benign metabolically healthy (MH) condition as opposed to a normal-weight but metabolically unhealthy (MUH) state.
Barile, A.   +10 more
core   +3 more sources

The Role of Micronutrients in Atherosclerosis: Mechanisms and Clinical Application

open access: yesJournal of Cellular and Molecular Medicine, Volume 29, Issue 21, November 2025.
ABSTRACT Micronutrients, though required in relatively small quantities by the human body, are essential for maintaining normal physiological functions and play a crucial role in the prevention and management of various diseases. Atherosclerosis (AS) is a common chronic inflammatory condition that often presents without obvious symptoms in its early ...
Yuxin Ouyang   +5 more
wiley   +1 more source

Nutrigenetics and Modulation of Oxidative Stress [PDF]

open access: yesAnnals of Nutrition and Metabolism, 2012
Oxidative stress develops as a result of an imbalance between the production and accumulation of reactive species and the body’s ability to manage them using exogenous and endogenous antioxidants. Exogenous antioxidants obtained from the diet, including vitamin C, vitamin E, and carotenoids, have important roles in preventing and reducing oxidative ...
Laura A, Da Costa   +2 more
openaire   +2 more sources

Epigenetic Mechanisms in Childhood Obesity

open access: yesAnnals of the New York Academy of Sciences, Volume 1553, Issue 1, Page 112-123, November 2025.
Abstract Epigenetic mechanisms, including DNA methylation, histone modification, and activity of noncoding RNAs (nc RNAs), affect the regulation of gene expression. These mechanisms are regulated by numerous environmental factors and are critical at specific windows of biological development, when organs and systems plasticity is increased.
Guadalupe León‐Reyes   +3 more
wiley   +1 more source

Transgénicos, nutrigenética y nutrigenómica en alimentación [PDF]

open access: yes, 2009
L'article explica l'abast dels termes relatius a la biotecnologia alimentària, i va dirigit als consumidors interessats a comprendre les noves àrees del coneixement sobre els aliments i als professionals del sector que volen estar al dia de les noves ...
Ramón Vidal, Daniel
core  

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