Results 51 to 60 of about 1,272 (135)
The Genetic Blueprint of Obesity: From Pathogenesis to Novel Therapies
Obesity Reviews, Volume 26, Issue 12, December 2025.ABSTRACT Obesity is a chronic metabolic disease characterized by disturbances in energy homeostasis, leading to excessive fat accumulation. The pathogenesis of the disease is shaped by a complex interplay of genetic, epigenetic, biological, psychological, and environmental factors.
Gašper Tonin +6 more
wiley +1 more source
The Role of Micronutrients in Atherosclerosis: Mechanisms and Clinical Application
Journal of Cellular and Molecular Medicine, Volume 29, Issue 21, November 2025.ABSTRACT Micronutrients, though required in relatively small quantities by the human body, are essential for maintaining normal physiological functions and play a crucial role in the prevention and management of various diseases. Atherosclerosis (AS) is a common chronic inflammatory condition that often presents without obvious symptoms in its early ...
Yuxin Ouyang +5 more
wiley +1 more source
Epigenetic Mechanisms in Childhood Obesity
Annals of the New York Academy of Sciences, Volume 1553, Issue 1, Page 112-123, November 2025.Abstract Epigenetic mechanisms, including DNA methylation, histone modification, and activity of noncoding RNAs (nc RNAs), affect the regulation of gene expression. These mechanisms are regulated by numerous environmental factors and are critical at specific windows of biological development, when organs and systems plasticity is increased.
Guadalupe León‐Reyes +3 more
wiley +1 more source
Type 2 diabetes mellitus: Clinical aspects of genetics, nutrigenetics, and pharmacogenetics
Терапевтический архив, 2015 The review gives modern knowledge of the genetics, pharmacogenetics and nutrigenetics of type 2 diabetes mellitus. The knowledge of genetic determinants can refine our understanding of the pathogenesis of this disease and introduce pharmacogenetic and ...
A S Ametov, L L Kamynina, Z G Akhmedova
doaj
Body fat and dairy product intake in lactase persistent and non-persistent children and adolescents
Food & Nutrition Research, 2010 Background : Lactase non-persistent (LNP) individuals may be lactose intolerant and therefore on a more restricted diet concerning milk and milk products compared to lactase persistent (LP) individuals. This may have an impact on body fat mass. Objective
Ricardo Almon +4 more
doaj +1 more source
Genetics and Molecular Biology, 2014 The individual response to diet may be influenced by gene polymorphisms. This study hypothesized that ADRB2 (Gln27Glu, rs1042714 and Arg16Gly, rs1042713), ADRB3 (Trp64Arg, rs4994) and GHRL (Leu72Met, rs696217) polymorphisms moderate weight loss.
Louise F. Saliba +7 more
doaj +1 more source
Euchembioj ReviewsThe worldwide prevalence of all cancer types continues to rise. In this context, the psychological burden of cancer—particularly anxiety and depression—has emerged as a critical yet frequently overlooked component of comprehensive oncological care.
Gulsen Meral +4 more
doaj +1 more source
DieteticsThe reciprocal relationship between genes and nutrients, known as nutrigenetics and nutrigenomics, has been established in many studies. However, current investigations of maternal and neonatal nutrition using a precision nutrition approach focused on ...
Dalia El Khoury +5 more
doaj +1 more source
Nutrition Journal, 2018 Background Significant associations between visceral fat and alterations in plasma fatty acids have been identified in overweight individuals. However, there are scant data regarding the relationships of the visceral fat area (VFA) with the plasma fatty ...
Young Ju Lee +7 more
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Resveratrol as an Inhibitor of Pregnane X Receptor (PXR): Another Lesson in PXR Antagonism
Journal of Pharmacological Sciences, 2014 .: The pregnane X receptor (PXR) plays a central role in the regulation of metabolism. Only few PXR antagonists have been described and the mechanism of PXR inhibition is mostly hypothetical or believed to be allosteric.
Tomas Smutny, Petr Pavek
doaj +1 more source