Results 101 to 110 of about 3,278,572 (299)

Mitochondria‐associated membranes (MAMs): molecular organization, cellular functions, and their role in health and disease

FEBS Open Bio, EarlyView.
Mitochondria‐associated membranes (MAMs) are contact sites between the endoplasmic reticulum and mitochondria that regulate calcium signaling, lipid metabolism, autophagy, and stress responses. This review outlines their molecular organization, roles in cellular homeostasis, and how dysfunction drives neurodegeneration, metabolic disease, cancer, and ...
Viet Bui, Maryline Santerre, Natalia Shcherbik, Bassel E Sawaya   +3 more
wiley   +1 more source

Nutrition-sensitive value chains: A guide for project design [PDF]

, 2019
A first-of-its-kind, this new Guide from IFAD presents practical, step-by-step guidance for shaping value chain projects to improve nutrition. The Guide highlights challenges and opportunities in establishing nutrition-sensitive value chains (NSVCs) and ...
International Fund for Agricultural Development
core  

Production of antibacterial compounds by a Steely hybrid polyketide synthase in Dictyostelium

FEBS Open Bio, EarlyView.
By selecting appropriate production species under optimised culture conditions, new chlorinated dibenzofuran compounds, which previously could not be analysed in sufficient quantities, were identified from cellular slime mould fruiting bodies. The strong antibacterial activity exhibited by these compounds suggests a link to the ecological function of ...
Tomoaki R. Yamashita, Toyonobu Usuki, Robert R. Kay, Tamao Saito   +3 more
wiley   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Scientific Opinion on the substantiation of a health claim related to iron and maintenance of normal hair growth pursuant to Article 13(5) of Regulation (EC) No 1924/2006

EFSA Journal, 2012
Following an application from Pierre Fabre Dermo‐Cosmétique, submitted pursuant to Article 13(5) of Regulation (EC) No 1924/2006 via the Competent Authority of France, the Panel on Dietetic Products, Nutrition and Allergies was asked to deliver an ...
EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA)
doaj   +1 more source

Calcium‐sensing receptor induces the apoptosis of chondrocytes in cooperation with phosphate transporter

FEBS Open Bio, EarlyView.
Excess Ca2+ ions activate the Calcium‐Sensing Receptor (CaSR), which subsequently drives the uptake of excess inorganic phosphate (Pi) via the Pi transporter (Pit−1) in chondrocytes. This mechanism causes a toxic increase in intracellular Pi concentration, ultimately leading to chondrocyte apoptosis and pathological mineralization. Excess extracellular
Sachie Nakatani, Hiroya Ueda, Ayumi Kawata, Yuki Sato, Kotomi Inomata, Hiroshi Mano, Masahiro Wada, Kenji Kobata   +7 more
wiley   +1 more source

Assessment of nutrition risk using the Mini-Nutritional Assessment Short-Form and biomarkers (prealbumin) in community-living older adults within Auckland : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Nutrition and Dietetics at Massey University, Albany, New Zealand [PDF]

, 2016
Background: The global population is ageing with New Zealand currently experiencing a large growth in those aged 65 years and older. Increasing age is associated with increasing use of health and disability support services. Vulnerable older adults are
Sycamore, Emily Louise
core  

SCAMP:standardised, concentrated, additional macronutrients, parenteral nutrition in very preterm infants: a phase IV randomised, controlled exploratory study of macronutrient intake, growth and other aspects of neonatal care [PDF]

, 2011
Background Infants born
A Dinerstein, A Grover, A Ogilvy-Stuart, A Riskin, AM Dusick, Anna Hart, B Koletzko, BB Poindexter, BE Stephens, BT Bloom, C Beecroft, C Fusch, C Morgan, Colin Morgan, CT Collins, DC Wilson, DG Mason, DM Hans, EKM Stoltz Sjöström, FWJ te Braake, FWJ te Braake, HM Ibrahim, IE Olsen, Isam Badhawi, JD Johnson, JE Dice, K Kotsopoulos, Kelly Mayes, M Ahmed, M Hack, M Hack, M Skouroliakou, MA Berry, MA Puago, Mark A Turner, Maw Tan, MJ Tan, MJ Tan, MY Yeung, N Murdock, NE Embleton, NS Wood, NS Wood, P Jadhav, PA Ball, Paul Newland, PJ Porcelli Jr, PJ Thureen, PJ Thureen, PJ Thureen, R Donovan, R Lenclen, RA Ehrenkranz, RA Ehrenkranz, RH Clark, RH Clark, RH Clarke, RJ Cooke, RW Cooke, RW Cooke, RW Cooke, S Eleni-dit-Trolli, S Kashyap, S Keady, SC Hartwig, Shakeel Herwitker, T Smolkin   +66 more
core   +3 more sources

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

FEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito, Masashi Arakawa, Koki Maeda, Eiji Morita   +3 more
wiley   +1 more source

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

FEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso, Jaime Hiniesta‐Valero, Alejandra Guerra‐Castellano, Miguel A. De la Rosa, Irene Díaz‐Moreno   +4 more
wiley   +1 more source