Results 51 to 60 of about 1,197,143 (282)

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Nutritional label use among patients with type 1 diabetes mellitus

, 2021
Background and Aims: In this study, it was aimed to evaluate the nutritional label use of individuals with type 1 DM. Material and Method: This cross-sectional descriptive study was conducted in November 2017 - June 2018.
AKTAÇ, ŞULE, GÜNEŞ, FATMA ESRA, CEBECİ, AYBİKE   +2 more
core   +1 more source

Discretizing continuous variables in nutrition and obesity research: a practice that needs to be cut short

Nutrition & Diabetes, 2023
Background/objectives Nutrition and obesity researchers often dichotomize or discretize continuous independent variables to conduct an analysis of variance to examine group differences.
Osvaldo F. Morera, Mosi I. Dane’el, Brandt A. Smith, Alisha H. Redelfs, Sarah L. Ruiz, Kristopher J. Preacher, Leah D. Whigham   +6 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Nutrition Labeling

Journal of Advance Research in Business Management and Accounting (ISSN: 2456-3544), 2016
This paper aims to highlight the importance of nutrition labeling. This FDA propose technique helps the consumers to make good nutrition choices. Application of Nutrition labeling is a must Therefore, the suggested model is particularly useful to understand the domain specific label utilization and its utmost importance.
openaire   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Nutritional labelling in restaurants: Whose responsibility is it anyway? [PDF]

International Journal of Contemporary Hospitality Management, 2010
PurposeThe purpose of this paper is to explore consumer attitudes towards the potential implementation of compulsory nutritional labelling on commercial restaurant menus in the UK.Design/methodology/approachThe research was approached from the perspective of the consumer with the intention of gaining an insight into personal attitudes towards ...
Alexander, Matthew, O'Gorman, Kevin D., Woods, Katie   +2 more
openaire   +3 more sources

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Profiles of Nutrition and Non – Nutrition Factors Related to Anemia Status Among Lactating Mothers in Jakarta [PDF]

, 2019
Background and Objective: Anemia is a major health problem affecting every phase of life. However less attention given to lactating mothers where anemia can give bad impacts to the mothers themselves and their babies.
Aulia, Diana, Wijaya, Reisa Melisa, Bardosono, Saptawati   +2 more
core   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source