Results 41 to 50 of about 3,173,119 (265)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Passiflora foetida yielding and nutritional composition

open access: yesRevista Brasileira de Fruticultura
Even though wild maracuja (Passiflora foetida) is cultivated in tropical areas, no thorough investigation regarding its yield or nutritional composition is easily available. This paper aims to estimate its fruit yield, using four staking systems; as well
Danilo Fernandes da Silva Filho   +5 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Establishing a nutrition calculation model for catering food according to the influencing factors of energy and nutrient content in food processing

open access: yesFrontiers in Nutrition
ObjectiveThis study aimed to establish an accurate and efficient scientific calculation model for the nutritional composition of catering food to estimate energy and nutrient content of catering food.MethodsWe constructed a scientific raw material ...
Nan Li   +9 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

NRS2002-stratified body composition and laboratory characteristics in hospitalized cancer patients assessed by bioelectrical impedance analysis

open access: yesFrontiers in Nutrition
ObjectiveThe body composition and laboratory characteristics underlying Nutritional Risk Screening 2002 (NRS2002)-defined nutritional risk in hospitalized patients with cancer remain insufficiently described.MethodsThis single-center retrospective cross ...
Ping Zhong   +5 more
doaj   +1 more source

Time-restricted eating in breast cancer survivors: Effects on body composition and nutritional status [PDF]

open access: yes, 2023
In this secondary analysis of an 8-week single-arm feasibility study of weekday time-restricted eating (TRE), we explored the effects of TRE on body composition. Women (n=22; ≥60 years) who had completed chemotherapy for early-stage breast cancer and had
Joy, Anil A.   +8 more
core   +1 more source

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Comparison of Major Nutritional Components in Polygonatum Germplasm Resources from Different Origins

open access: yesFoods
Polygonatum has been widely used in traditional Chinese medicine and as a functional food due to its richness in bioactive compounds and nutritional value.
Yihong Li   +3 more
doaj   +1 more source

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