Results 81 to 90 of about 202,254 (268)

EPIDEMIOLOGICAL AND NUTRITIONAL PROFILE OF HOME ENTERAL NUTRITION USERS

Demetra, 2014
A terapia nutricional em ambiente domiciliar contribui para a recuperação do estado de saúde do paciente, além de apresentar menor custo quando comparada à nutrição enteral hospitalar. Entretanto, na prática clínica, percebe-se que os pacientes e familiares possuem dificuldades para executar os procedimentos relacionados à nutrição enteral.
Ana Claúdia Silva, Simonton de Andrade Silveira   +1 more
openaire   +1 more source

Overcoming Photodynamic Therapy Resistance: GSH‐Responsive AIE Photosensitizer‐Hydroxycamptothecin Nanoliposomes for Extrahepatic Cholangiocarcinoma

Advanced Healthcare Materials, EarlyView.
A GSH‐responsive AIE nanoplatform (TSH NPs) with RGD‐mediated tumor targeting co‐delivers a photosensitizer (TPA) and HCPT for extrahepatic cholangiocarcinoma. The system synergistically enhances PDT and chemotherapy by suppressing HIF‐1α/VEGF‐driven hypoxic adaptation, effectively overcoming PDT resistance.
Yong Qu, Tao Peng, Yating Zhang, Juanmei Cao, Birong Wang, Chuxing Chai, Zhiyuan Gao, Yiting Xu, Yifan Jin, Yuqing Wang, Zhuoxia Li, Xu Liu, Tianqi Zhao, Yufan Chen, Weimin Lv, Di Lu, Changzheng Huang, Dan Ding, Jinxiang Zhang, Min Li   +19 more
wiley   +1 more source

Cross Kingdom Metabolic Engineering Paradigm Elevating Sustainable Protein Production

Advanced Science, EarlyView.
ABSTRACT Confronting the dual crisis of escalating global protein demand and unsustainable agriculture necessitates transformative solutions. Here, we pioneer evolutionary insights from maize nitrogen optimization via asparagine synthetase (ASNS) to rewire metabolism in Pichia pastoris.
Yuanyuan Du, Changyu Pi, Kai Hong, Le Gao, Xin Wu   +4 more
wiley   +1 more source

The Nutritional Quality of Commercially Bred Yellow Mealworm (Tenebrio molitor) Compared to European Union Nutrition Claims

Insects
Due to its potential as a sustainable protein source, the industrial relevance of Tenebrio molitor, known as yellow mealworm, is set to increase substantially.
Isabelle Noyens, Meggie Van Peer, Sarah Goossens, Carmen Ter Heide, Sabine Van Miert   +4 more
doaj   +1 more source

Mitochondrial Dysfunction Unravels the Potential Molecular Link Between Night Shift Work‐Related Circadian Disruption and Elevated Blood Pressure in Human and Mouse Models

Advanced Science, EarlyView.
This diagram illustrates that night shift work disrupts circadian clock genes (like CLOCK, BMAL1) in both humans and mice. This disruption leads to mitochondrial dysfunction (imbalanced fusion/fission proteins) and increased oxidative stress, which is identified as the primary mechanism ultimately causing elevated blood pressure.
Zhaoqiang Jiang, Yifan Dou, Yingnan Lei, Shuang Liu, Jialin Zhou, Jiaping Li, Huadong Xu, Lingfang Feng, Yongxin Li, Chuyan Zhang, Tao Li, Jianfei Wang, Xing Zhang, Xinran Wang, Luyao Liu, Jingjing Zhang, Jianlin Lou   +16 more
wiley   +1 more source

Formulation of a High-Quality Cold-Pressed Vegetable Oil (Virgin) Based on a Blend of Four Oilseeds

Foods
Vegetable oils are crucial for the human diet, providing energy and essential fatty acids. This study investigates the formulation of a high-quality cold-pressed vegetable oil blend from rapeseed, sunflower, sesame, and safflower, chosen for their ...
Ibtissame Guirrou, Abderraouf El Antari, Abdelhay El Harrak, Abdelghani Nabloussi   +3 more
doaj   +1 more source

Evaluation of the Physicochemical, Functional, Structural, and Anti-Nutritional Composition of Germinated Underutilized Fox nut Seed Flour [PDF]

BIO Web of Conferences
Germination was explored in this study as a natural method of increasing the nutritional and functional content of foxnut (Euryale ferox) seeds. Germination resulted in significant increases in the nutritional content of the seeds.
Bisht Himani, Singh Karuna, Islam Zoobiya   +2 more
doaj   +1 more source

Single‐Cell Dissection of Therapy‐Induced Remodeling Uncovers a Fibroblast‐Driven Immunosuppressive Niche and Targetable Vulnerabilities in Lethal Prostate Cancer

Advanced Science, EarlyView.
Single‐cell longitudinal profiling reveals that androgen‐deprivation therapy induces a DPT+ fibroblast‐complement axis that suppresses macrophage inflammation and drives CD8+ T cell exhaustion in prostate cancer. Concurrently, resistant epithelial subpopulations persist and engage TSPAN1‐ and NRXN1‐mediated programs promoting CRPC and neuroendocrine ...
Yang Chen, Dandan Dong, Jinling Liao, Naikai Liao, Mengqi Liu, Qin Zhang, Siting Chen, Qi Liu, Ying Lu, Tianyu Li, Chunlin Zou, Qiong Song, Qiuyan Wang, Jian Liang, Qiji Xie, Chengyang Li, Mengyun Wang, Jiwen Cheng, Zengnan Mo, Gong‐Hong Wei   +19 more
wiley   +1 more source

Bio-impedancemetry an essential tool in the obesity screening of patients with chronic renal failure [La bio-impédancemétrie un outil indispensable dans le dépistage de l’obésité chez les patients en insuffisance rénale chronique]

Nutrition & Santé
Introduction. The survival of patients with chronic kidney disease (CKD) depends on several factors, abnormal nutritional status such as obesity or protein-energy malnutrition are among these factors.
Samia BOUDANI, Faiza ZERDOUMI, Naouel FZ. BOUMANSOUR, Abbou KADDOUS, Bachir M. GUELLIL   +4 more
doaj   +1 more source

Unveiling Lactylation: A Novel Frontier in Cancer Stemness and Therapy

Advanced Science, EarlyView.
Tumor metabolism and epigenetic regulation are intrinsically linked. This review highlights lactylation as a pivotal bridge connecting these processes, acting as an active epigenetic effector in cancer stemness. We delineate how lactylation orchestrates the cancer stem cell landscape and evaluate its regulatory networks.
Ting Li, Hongyu Gu, Chang Liu, Yuesheng Lv, Feifei Li, Liang Liang, Jia Yi, Xuanyi Wang, Yi Zhun Zhu, Chuan Xu   +9 more
wiley   +1 more source