Results 41 to 50 of about 3,991,247 (327)

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Níveis nutricionais de cálcio e fósforo disponível para aves de reposição leves e semipesadas de 0 a 6 semanas de idade Nutritional levels of calcium and available phosphorus for white-egg pullets and brown-egg pullets from 0 to 6 weeks of age

Revista Brasileira de Zootecnia, 2003
Foram realizados quatro experimentos utilizando 720 aves leves e 720 aves semipesadas de 0 a 6 semanas de idade, distribuídas em um delineamento inteiramente ao acaso, com cinco níveis de cálcio (0,70; 0,80; 0,90; 1,00 e 1,10%) ou com cinco níveis de ...
José Geraldo de Vargas Junior, Luiz Fernando Teixeira Albino, Horacio Santiago Rostagno, Paulo Cézar Gomes, Edwiney Sebastião Cupertino, Débora Cristine Oliveira Carvalho, Adriana Helena do Nascimento   +6 more
doaj   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

Co‐overexpression of the caloric restriction‐induced mitochondrial factors PGC‐1α and MIPEP upregulates Phospho1 expression in adipocytes

FEBS Open Bio, EarlyView.
Caloric restriction that extends lifespan induces the expression of PGC‐1α and MIPEP in white adipose tissue. In this study, co‐overexpression of Pgc‐1α and Mipep upregulated the gene expression of PHOSPHO1. These findings provide new insights into mitochondria‐related mechanisms underlying the effects of caloric restriction in adipocytes.
Mamiko Ishimatsu, Kanari Taki, Asuka Hayami, Komachi Kato, Yuka Nozaki, Yuhei Mizunoe, Takumi Narita, Ryoichi Mori, Yoshikazu Higami, Masaki Kobayashi   +9 more
wiley   +1 more source

Nutritional requirements of sheep, goats and cattle in warm climates: a meta-analysis.

Animal, 2014
The objective of the study was to update energy and protein requirements of growing sheep, goats and cattle in warm areas through a meta-analysis study of 590 publications.
N. Salah, D. Sauvant, H. Archimède
semanticscholar   +1 more source

Cis‐unsaturated sphingolipids support growth of sphingoid base‐deficient yeast but impair plasma membrane integrity

FEBS Open Bio, EarlyView.
Sphingoid base structures, the sphingolipid backbones, vary among species. We established yeast cells in which the native sphingoid base was replaced with plant‐type bases containing cis or trans double bonds. This is, to our knowledge, the first eukaryotic model mostly composed of sphingolipids containing cis‐unsaturated sphingoid base, providing a ...
Takashi Higuchi, Saki Sugihara, Yohei Ishibashi, Kono Yushi, Hazuki Yamauchi, Motohiro Tani   +5 more
wiley   +1 more source

Fetal Akinesia/Hypokinesia and Arthrogryposis of Neuromuscular Origin: Etiologic Groups, Genetics, and Phenotypic Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To provide a comprehensive clinical and genetic characterization of individuals with arthrogryposis multiplex congenita (AMC), focusing on the distribution of genetic etiologies across the neuromuscular spectrum and comparing myogenic and neurogenic subtypes. Methods A total of 105 individuals with AMC were clinically and genetically
Florencia Pérez‐Vidarte, Berta Estévez‐Arias, Leslie Matalonga, Delia Yubero, Anna Codina, Carlos Ortez, Julita Medina, Lidia DeSena DeCabo, Laura Carrera‐García, Jesica Expósito‐Escudero, Cristina Jou, Eduardo F. Tizzano, Andres Nascimento, Daniel Natera‐de Benito   +13 more
wiley   +1 more source

Exigência de sódio para frangos de corte nas fases de crescimento (22 a 42 dias) e final (43 a 53 dias) Sodium requirement for broilers in the growing (from 22 to 42 days) and finishing (from 43 to 53 days) phases

Revista Brasileira de Zootecnia, 2004
Com o objetivo de determinar as exigências de sódio para frangos de corte durante as fases de crescimento e final, foram utilizados, respectivamente, 720 e 600 frangos, machos e fêmeas, nos períodos de 22 a 42 e de 43 a 53 dias de idade, submetidos a uma
José Mauricio Sthel de Barros, Paulo Cezar Gomes, Luiz Fernando Teixeira Albino, Horacio Santiago Rostagno, Leidimara Feregueti Costa   +4 more
doaj   +1 more source

Correlation Between Irisin and Cognitive Functions in Alzheimer Dementia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The myokine irisin, a recent positive mediator of exercise in the brain, shows neuroprotective functions against Alzheimer's disease (AD). The association between irisin and cognition has never been explored in a biologically defined cohort of patients.
Patrizia Pignataro, Manuela Dicarlo, Chiara Zecca, Daniele Urso, Maria Teresa Dell'Abate, Davide Vilella, Francesco Borlizzi, Roberta Zerlotin, Angela Oranger, Graziana Colaianni, Silvia Colucci, Maria Grano, Giancarlo Logroscino   +12 more
wiley   +1 more source

Feed intake and prediction assessments using the NRC, CNCPS and BR-CORTE systems in Nellore and Red Norte steers finished in feedlot Consumo alimentar e avaliação das predições pelos sistemas NRC, CNCPS e BR-CORTE em novilhos Nelore e Red Norte terminados em confinamento

Revista Brasileira de Zootecnia, 2010
The objective of this research was to evaluate the dry matter intake (DMI) and nutrient consumption in Nellore and Red Norte steer finished in a feedlot and compare the actual and predicted values by NRC (2000), CNCPS 5.0 and BR-CORTE systems.
Otávio Rodrigues Machado Neto, Márcio Machado Ladeira, Tarcisio de Moraes Gonçalves, Leandro Sâmia Lopes, Dalton Mendes de Oliveira, Marcelo Silva Bassi   +5 more
doaj   +1 more source