Results 41 to 50 of about 707,832 (362)

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

Molecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin, Audrey Vinchent, Marie Fernandes, Isabelle Damour, Agathe Laratte, Rémi Tellier, Gabriella O. Estevam, Jean‐Pascal Meneboo, Céline Villenet, Clotilde Descarpentries, James S. Fraser, Martin Figeac, Alexis B. Cortot, Etienne Rouleau, David Tulasne   +14 more
wiley   +1 more source

Methionine plus Cystine Levels for Light Laying Hens on Growth Phase

Revista Principia, 2021
The aim of this study was to evaluate the methionine plus cystine levels in the diets of laying hens during the rearing period (13-18 weeks old). The diets included a control diet formulated according to NRC and five other diets with different levels of ...
Marcelo Helder Medeiros Santana, Fernando Guilherme Perazzo Costa, Ricardo Romão Guerra, Jalceyr Pessoa Figueiredo Júnior, Matheus Ramalho de Lima, Sarah Gomes Pinheiro   +5 more
doaj   +1 more source

UMDFood: Vision-language models boost food composition compilation [PDF]

arXiv, 2023
Nutrition information is crucial in precision nutrition and the food industry. The current food composition compilation paradigm relies on laborious and experience-dependent methods. However, these methods struggle to keep up with the dynamic consumer market, resulting in delayed and incomplete nutrition data.
arxiv  

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

Molecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé, Lisa Hahnefeld, Katharina J. Wenger, Donat Kögel, Joachim Steinbach, Gerd Geisslinger, Michael W. Ronellenfitsch, Irmgard Tegeder   +7 more
wiley   +1 more source

Progresso científico sobre nutrição de animais de companhia na primeira década do século XXI Scientific progress on companion animal nutrition on the first decade of the Century XXI

Revista Brasileira de Zootecnia, 2010
O conhecimento científico sobre nutrição de animais de companhia tem aumentado de forma contínua, acompanhando o fenômeno visto em diversas áreas de conhecimento.
Aulus Cavalieri Carciofi, Juliana Toloi Jeremias   +1 more
doaj   +1 more source

Differential pathways to adult metabolic dysfunction following poor nutrition at two critical developmental periods in sheep

, 2014
Epidemiological and experimental studies suggest early nutrition has long-term effects on susceptibility to obesity, cardiovascular and metabolic diseases.
Brewin, Andrew, Burdge, Graham C., Cleal, Jane K., Fulford, Laurence, Green, Lucy R., Hanson, Mark A., Hollis, Lisa J., Lillycrop, Karen A., Murray, Robert J.S., Poore, Kirsten R., Warlow, Anna   +10 more
core   +3 more sources

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

Graduate Student Literature Review: Considerations for nutritional grouping in dairy farms*

Journal of Dairy Science, 2022
: Each cow in a group has different nutritional requirements even if the group is formed by cows of similar age, number of lactations, and lactation stage.
Jorge A. Barrientos-Blanco, Heather White, Randy D. Shaver, Victor E. Cabrera   +3 more
doaj  

ASPECTOS NUTRICIONALES DE PECES ORNAMENTALES DE AGUA DULCE

Revista Politécnica, 2019
The commercialization of ornamental fish has become an economic activity of great importance for aquaculture worldwide. This document seeks to collect and highlight the importance of nutritional aspects such as the type of food, the essential nutrients ...
Juan Sebastian Velasco-Garzón, Mariana Catalina Gutiérrez-Espinosa   +1 more
doaj   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source