Results 111 to 120 of about 2,530 (193)

HnRNPA2B1 ISGylation Regulates m6A‐Tagged mRNA Selective Export via ALYREF/NXF1 Complex to Foster Breast Cancer Development

Advanced Science
Regulating nuclear export precisely is essential for maintaining mRNA homeostasis and impacts tumor progression. However, the mechanisms governing nuclear mRNA export remain poorly elucidated.
Ting Jin, Liping Yang, Chao Chang, Haojun Luo, Rui Wang, Yubi Gan, Yan Sun, Yuetong Guo, Rui Tang, Shanchun Chen, Die Meng, Peijin Dai, Manran Liu   +12 more
doaj   +1 more source

IE4 exports pDM128 mRNAs in a TAP/NXF1-dependent manner.

, 2013
(A) Schematic representation of the pDM128 reporter plasmid in which the CAT coding sequence is inserted into an intronic sequence (adapted from Hiriart et al. 2003).
Cahora Medina-Palazon (369300), Jacques Piette (56234), Patricia Vandevenne (356249), Marielle Lebrun (150806), Catherine Sadzot-Delvaux (83664), Sébastien Bontems (83665), Isabelle Ote (356252), Evelyne Manet (369302)   +7 more
core   +1 more source

Drug repositioning for pan-cancers of the digestive system: Identification of amonafide and BX795 as potential therapeutics via integrative Omics analysis.

PLoS ONE
BackgroundDigestive system cancers, including esophageal, gastric, colorectal, pancreatic, hepatocellular, and biliary tract cancers, constitute a major global health challenge.
Weidong Liu, Jiaying Gao, Shuqiang Ren, Buhe Nashun, Fei Gao   +4 more
doaj   +1 more source

68. NXF1 Controls Nuclear Export of Spliced and Unspliced Gammaretroviral Transcripts [PDF]

Molecular Therapy, 2013
openaire   +1 more source

NXF1 regulates ELAVL1 and CRM1 expression to support HBV RNAs nucleocytoplasmic transport.

(A-E) NXF1 knockdown HepG2-NTCP cells were pretreated with 2.5% DMSO for 2 days following HBV infection at an MOI of 200 and were maintained with DMEM containing 2.5% DMSO for 7 days. (A) Knockdown efficiency of was confirmed by WB. (B) Levels of HBV DNA
Chuanjian Wu (15877596), Jingjing Wang (140791), Xiaoming Cheng (556761), Jiatong Yin (17896706), Xiyu Hu (3385730), Yurong Duan (362841), Guoguo Zhu (719139), Kaitao Zhao (3617825), Mengfei Wang (4899196), Yanan Bu (15877590), Quan Chen (163802), Yanping Xu (788986), Rong Hua (325799), Lu Zhang (50563), Yuchen Xia (9287840), Zaichao Xu (15877593), Yingcheng Zheng (8381655)   +16 more
core   +1 more source

Nuclear speckles are regulatory hubs for viral and host mRNA expression during HSV-1 infection. [PDF]

Proc Natl Acad Sci U S A
Nadav-Eliyahu S, Bohrer C, Boocholez A, Kinor N, Aho V, Benichou JIC, Mattola S, Salminen S, Niskanen H, Kaikkonen MU, Vihinen-Ranta M, Shav-Tal Y.   +11 more
europepmc   +1 more source

RNA export through the nuclear pore complex: pathways, mechanisms, and imaging strategies. [PDF]

RNA Biol
Fu D, Yu W, Zhang F, Rush C, Tingey M, Yang W.   +5 more
europepmc   +1 more source

Escorting mRNAs - the multifunctional and divergent roles of cap-chaperones in post-transcriptional gene expression. [PDF]

J Cell Sci
Embree CM, Borden KLB.
europepmc   +1 more source

Molecular insights into mRNA export regulation by the human TREX-2 complex. [PDF]

Nat Commun
Gong X, Tao R, Ge X, Zhu H, Li M, Chen Y, Gao Y, Hang J, Zhang X.   +8 more
europepmc   +1 more source

Robust single-molecule tracking of RNA abundance and dynamics via TSSOT. [PDF]

iScience
Luo Y, Fu Y, Wang J, Li S, Cheng T, Pi C, Qiao C, Zou W, Liu N, Wang X, Chen B.   +10 more
europepmc   +1 more source