Results 91 to 100 of about 2,530 (193)
Novel insights on the positive correlation between sense and antisense pairs on gene expression
WIREs RNA, Volume 15, Issue 4, July/August 2024.Distinct modes of regulation between sense/antisense transcripts. The expression of sense transcripts can be regulated by corresponding antisense transcripts either a discordant/negative regulatory mechanism or a concordant/positive regulatory mechanism (Created with BioRender.com).
Subhadeep Das +2 more
wiley +1 more source
Nxf1CAST congenic allele suppresses a diversity of IAP elements in the B6 genome.
, 2015 (A) Schematic diagrams illustrate sequence compositions of IAP elements in this study. Deleted segments in each elements compared with full-length consensus are shown at 10% opacity.
Kevin D. Ross (716891) +4 more
core +1 more source
, 2014 A) The NXF1-p15 complex can associate with HBV specific RNAs by the RNA-IP assay. HuH-7 cells were co-transfected with plasmid DNAs of an HBV genome, NXF1-Flag, and p15-Flag.
Chiaho Shih (172769) +4 more
core +1 more source
Nxf1 alleles do not affect alternative processing at non-IAP sites.
, 2015 (A) The ratio of alternative splice forms for 12 candidate genes was measured by in-gel fluorescence after PCR from congenic Nxf1CAST or Nxf1B6 allele homozygotes. Box-and-whiskers plots show the ratio ratio between paired samples of alternate genotypes (
Kevin D. Ross (716891) +4 more
core +1 more source
Tpr mediated regulation of unspliced RNA export is independent of Tap/Nxf1 and Sam68's functions.
, 2012 (A) Cells were transfected with 1 µg of siRNA against either Sam68 or Tap/Nxf1 along with NS-Si or TSi. The cells were replated the next day and 24 hours after replating, the cells were transfected once again with siRNA oligos and the reporter constructs.
Vinay Kumar Nandicoori (187989) +1 more
core +1 more source
, 2016 (A) Depiction of 24xMBL-bearing ΔEE HIV-1 gRNAs expressed with or without MS2-tagged fusion proteins in HeLa.MS2-YFP cells. (B) MS2-Rev expression led to ΔEE-gRNA evacuation from the nucleus (MS2-YFP signal in green), while MS2-NXF1 expression directed ...
Nathan M. Sherer (86591) +4 more
core +1 more source
HIV-1 Rev protein specifies the viral RNA export pathway by suppressing TAP/NXF1 recruitment. [PDF]
, 2014 Nuclear RNA export pathways in eukaryotes are often linked to the fate of a given RNA. Therefore, the choice of export pathway should be well-controlled to avoid an unfavorable effect on gene expression.
Mabuchi, Naoto +2 more
core +1 more source
CASC3 suppresses mRNA nuclear export through interacting with export receptor NXF1
, 2022 CASC3 는 특이적 서열 독립적으로 엑손-엑손 경계의 ~20-24 nt 상류에 위치하는 Exon junction complexes의 핵심 구성 요소 중 하나이다. CASC3는 핵과 세포질 왕복 단백질이고 거의 독점적으로 엑손-엑손 접합부의 20-24 nt 상류에서 RNA와 접촉한다.
Jiyeon Ha
core +1 more source
Retrovirology, 2009 Retroviruses have evolved multiple strategies to direct the synthesis of a complex proteome from a single primary transcript. Their mechanisms are modulated by a breadth of virus-host interactions, which are of significant fundamental interest because ...
Boris-Lawrie Kathleen, Bolinger Cheryl
doaj +1 more source
Interference with the NXF1-p15 complex reduced HBV DNA synthesis.
, 2014 HuH-7 cells were transiently co-transfected with an HBV genome (plasmid pCHT-9/3091) and siRNAs, followed by Southern blot analysis using HBV probe (nt 1521–3164) (Fig. 1).
Chiaho Shih (172769) +4 more
core +1 more source