Results 171 to 180 of about 2,530 (193)
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Dm nxf1/sbr gene affects the formation of meiotic spindle in female Drosophila melanogaster
Chromosome Research, 2009The small bristles (sbr) gene of Drosophila melanogaster belongs to the family of nuclear export factor (NXF) genes that participate in mRNA nuclear export. During meiosis, females of Drosophila melanogaster that carry various combinations of mutant alleles of the Dm nxf1/sbr gene exhibit disruption of the division spindle and misalignment of ...
Elena V, Golubkova +5 more
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Journal of Molecular Biology, 2003
The mRNA nuclear export function of Tap/NXF1 requires interactions with nuclear pore proteins (nucleoporins) that contain characteristic Phe-Gly repeats based on FG, GLFG or FxFG cores separated by hydrophilic linkers. FG-nucleoporins bind the two most C-terminal domains of Tap, which have NTF2 and UBA folds, respectively.
Richard P, Grant +2 more
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The mRNA nuclear export function of Tap/NXF1 requires interactions with nuclear pore proteins (nucleoporins) that contain characteristic Phe-Gly repeats based on FG, GLFG or FxFG cores separated by hydrophilic linkers. FG-nucleoporins bind the two most C-terminal domains of Tap, which have NTF2 and UBA folds, respectively.
Richard P, Grant +2 more
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XIST RNA exhibits nuclear retention and exhibits reduced association with the export factor TAP/NXF1
Chromosoma, 2007During splicing and polyadenylation, factors that stimulate export from the nucleus are recruited to nascent mRNAs. X-inactive specific transcript (XIST) RNA is unusual among capped, spliced, polyadenylated transcripts in that it accumulates exclusively in the nucleus.
Hannah R, Cohen, Barbara, Panning
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Cell and Tissue Biology, 2010
Spermatogenesis in both the model object Drosophila melanogaster and mammals, including humans, is characterized by the specificity of the regulation of gene expression at both the transcriptional and translational levels, which is manifested in the existence of testis-specific transport mRNA receptors, NXF (nuclear export factor).
A. A. Atsapkina +5 more
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Spermatogenesis in both the model object Drosophila melanogaster and mammals, including humans, is characterized by the specificity of the regulation of gene expression at both the transcriptional and translational levels, which is manifested in the existence of testis-specific transport mRNA receptors, NXF (nuclear export factor).
A. A. Atsapkina +5 more
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Biochemical and Biophysical Research Communications, 2004
Hu proteins are RNA-binding proteins that are implicated in the control of stabilization, nuclear export, and/or translation of specific mRNAs with AU-rich elements (AREs) in the 3'-untranslated region. Three neuron-specific Hu proteins (HuD, HuB, and HuC), but not a ubiquitously expressed Hu protein HuR, have an activity to induce neurite outgrowth ...
Kuniaki, Saito +4 more
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Hu proteins are RNA-binding proteins that are implicated in the control of stabilization, nuclear export, and/or translation of specific mRNAs with AU-rich elements (AREs) in the 3'-untranslated region. Three neuron-specific Hu proteins (HuD, HuB, and HuC), but not a ubiquitously expressed Hu protein HuR, have an activity to induce neurite outgrowth ...
Kuniaki, Saito +4 more
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Анализ генов семейства nxf1, контролирующих транспорт рнк
This study conducted a comprehensive investigation of the Nxf1 genes across an evolutionarily broad range of organisms to assess its potential as an evolutionary marker. Special attention was given to analyzing various structural features, including mRNAs with conserved introns, which revealed novel regulatory mechanisms.openaire +1 more source
NXF1/p15 heterodimers are essential for mRNA nuclear export in Drosophila.
RNA (New York, N.Y.), 2002The conserved family of NXF proteins has been implicated in the export of messenger RNAs from the nucleus. In metazoans, NXFs heterodimerize with p15. The yeast genome encodes a single NXF protein (Mex67p), but there are multiple nxf genes in metazoans.
A, Herold, T, Klymenko, E, Izaurralde
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Tsitologiia, 2010
Specificity of regulation of genes expression at the transcriptional and posttranscriptional levels is typical for spermatogenesis in Drosophila and mammals, including humans. It becomes apparent in the existence of testis specific NXF (nuclear export factor). We have shown that the Dm NXF1 (SBR) protein is present in considerable amounts at all stages
A A, Atsapkina +5 more
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Specificity of regulation of genes expression at the transcriptional and posttranscriptional levels is typical for spermatogenesis in Drosophila and mammals, including humans. It becomes apparent in the existence of testis specific NXF (nuclear export factor). We have shown that the Dm NXF1 (SBR) protein is present in considerable amounts at all stages
A A, Atsapkina +5 more
openaire +1 more source
The
ABSTRACT The neuronal ELAV protein HuD is known to promote neuronal differentiation and stimulate cap‐dependent translation, but the underlying mechanism remains incompletely understood. Here, we identify a functional domain within the HuD linker that governs interaction with the nuclear export factor TAP/NXF1 and stimulates ...
So, Toshima +5 more
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