Results 231 to 240 of about 14,762,033 (298)

Biomarkers of lung congestion and injury in acute heart failure

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 781-789, April 2025.
Abstract Acute heart failure (AHF) classification and management are primarily based on lung congestion and/or hypoperfusion. The quantification of the vascular and tissue lung damage is not standard practice though biomarkers of lung injury may play a relevant role in this context.
Marco Guazzi   +9 more
wiley   +1 more source

Chelation‐Assisted Metal‐Catalyzed Ligation and Cleavage Reactions for Chemical Biology

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
Chelation‐assisted transition metal catalysis has emerged as a promising complement to bioorthogonal click chemistry for studying biological processes. By pre‐organizing catalytic metal centers, designed coordinating substrates enhance reactivity and biocompatibility, enabling site‐selective ligation and decaging reactions in complex biological media ...
Emilie Plantiveau   +3 more
wiley   +1 more source

The Expanding Role of Diazirines in Synthetic Methodology

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
Beyond their established role in photoaffinity labeling, diazirines have emerged as versatile reagents in synthetic chemistry. This review highlights their dual reactivity as carbene and nitrogen‐transfer precursors, showcasing mechanistic insights and diverse applications in cyclopropanations, cycloadditions, skeletal editing, amination, heterocycle ...
Viktor Savic   +3 more
wiley   +1 more source

MOTAI: A Novel Method for the Study of O-GalNAcylation and Complex O-Glycosylation in Cancer. [PDF]

open access: yesAnal Chem
Yue S   +13 more
europepmc   +1 more source

Synthesis of α‐C‐Glycoside Conjugates Promoted by 4CzIPN‐Based Porous Organic Polymers Through Giese‐Like Reaction of Glycosyl Bromides in Batch and Continuous Flow

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
Visible light and a 4CzIPN‐based porous organic polymer (4CzIPN‐POP) enable Giese‐like coupling of glycosyl bromides with electron‐poor alkenes to access α‐C‐glycoside conjugates. The study shows how heterogeneous thermally activated delayed fluorescence photocatalysis can be combined with continuous flow to overcome light penetration limits and ...
Francesco Riina   +6 more
wiley   +1 more source

Inherited metabolic epilepsies–established diseases, new approaches

open access: yesEpilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

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