Enhanced O-glycosylation site prediction using explainable machine learning technique with spatial local environment. [PDF]
Hong S +4 more
europepmc +1 more source
Biomarkers of lung congestion and injury in acute heart failure
Abstract Acute heart failure (AHF) classification and management are primarily based on lung congestion and/or hypoperfusion. The quantification of the vascular and tissue lung damage is not standard practice though biomarkers of lung injury may play a relevant role in this context.
Marco Guazzi +9 more
wiley +1 more source
B3GNT7 regulates mucin O-glycosylation to alleviate colonic inflammation. [PDF]
Wang T, Sun H, Zhang M, Shen P, Li Y.
europepmc +1 more source
Chelation‐Assisted Metal‐Catalyzed Ligation and Cleavage Reactions for Chemical Biology
Chelation‐assisted transition metal catalysis has emerged as a promising complement to bioorthogonal click chemistry for studying biological processes. By pre‐organizing catalytic metal centers, designed coordinating substrates enhance reactivity and biocompatibility, enabling site‐selective ligation and decaging reactions in complex biological media ...
Emilie Plantiveau +3 more
wiley +1 more source
The Expanding Role of Diazirines in Synthetic Methodology
Beyond their established role in photoaffinity labeling, diazirines have emerged as versatile reagents in synthetic chemistry. This review highlights their dual reactivity as carbene and nitrogen‐transfer precursors, showcasing mechanistic insights and diverse applications in cyclopropanations, cycloadditions, skeletal editing, amination, heterocycle ...
Viktor Savic +3 more
wiley +1 more source
MOTAI: A Novel Method for the Study of O-GalNAcylation and Complex O-Glycosylation in Cancer. [PDF]
Yue S +13 more
europepmc +1 more source
Visible light and a 4CzIPN‐based porous organic polymer (4CzIPN‐POP) enable Giese‐like coupling of glycosyl bromides with electron‐poor alkenes to access α‐C‐glycoside conjugates. The study shows how heterogeneous thermally activated delayed fluorescence photocatalysis can be combined with continuous flow to overcome light penetration limits and ...
Francesco Riina +6 more
wiley +1 more source
GFPT1 accelerates immune escape in breast cancer by modifying PD-L1 via O-glycosylation. [PDF]
Tang W, Gao Y, Hong S, Wang S.
europepmc +1 more source
Inherited metabolic epilepsies–established diseases, new approaches
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley +1 more source
Ultrastructural and glycoproteomic characterization of Prevotella intermedia: Insights into O-glycosylation and outer membrane vesicles. [PDF]
Ye X +5 more
europepmc +1 more source

