Results 91 to 100 of about 183,803 (290)

Rapid generation of Shigella flexneri GMMA displaying natural or new and cross-reactive O-Antigens. [PDF]

open access: yesNPJ Vaccines, 2022
Gasperini G   +9 more
europepmc   +1 more source

Effect of Cholesterol on Antigenicity of Streptolysin O.

open access: yesExperimental Biology and Medicine, 1950
Summary1. The observation of Hewitt and Todd that cholesterol neutralizes the hemolytic activity of streptolysin O is confirmed.2. The antigenicity of streptolysin O remains unchanged in cholesterol-neutralized mixtures.3. Under similar conditions streptolysin O neutralized by its specific antibody elicits virtually no immune response to streptolysin O.
G. S. Turner, E. Irene Pentz
openaire   +2 more sources

Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value

open access: yesMolecular Oncology, EarlyView.
The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song   +13 more
wiley   +1 more source

Avaliação de antígenos de Cysticercus cellulosae no imunodiagnóstico da cisticercose humana pela hemaglutinação indireta Evaluation of antigens from Cysticercus cellulosae for immunodiagnosis of human cysticercosis by hemagglutination test

open access: yesRevista do Instituto de Medicina Tropical de São Paulo, 1984
Os Autores avaliaram os antígenos de Cysticercus cellulosae para o imunodiagnóstico da cistieercose humana pela reação de hemaglutinação indireta.
E. Nascimento, W. Mayrink
doaj  

Fusion protein-based COVID-19 vaccines exemplified by a chimeric vaccine based on a single fusion protein (W-PreS-O)

open access: yesFrontiers in Immunology
In this article we discuss characteristics of fusion protein-based SARS-CoV-2 vaccines. We focus on recombinant vaccine antigens comprising fusion proteins consisting of combinations of SARS-CoV-2-derived antigens or peptides or combinations of SARS-CoV ...
Pia Gattinger   +17 more
doaj   +1 more source

ABO BLOOD GROUP SYSTEM: IN THE CONTEXT OF HUMAN DISEASES [PDF]

open access: yesKanem Journal of Medical Sciences, 2018
Background: The expression of ABO blood group antigens on red cell surface and a variety of human cells, tissues and fluids is well documented. Studies in the recent times have reported association between these blood group antigens and some disorders in
Obi SO   +8 more
doaj  

Function-guided selection of salivary antigens from Ornithodoros erraticus argasid ticks and assessment of their protective efficacy in rabbits

open access: yesTicks and Tick-Borne Diseases, 2023
The identification of new protective antigens for the development of tick vaccines may be approached by selecting antigen candidates that have key biological functions.
Ángel Carnero-Morán   +3 more
doaj  

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi   +26 more
wiley   +1 more source

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

open access: yesMolecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam   +9 more
wiley   +1 more source

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