Results 111 to 120 of about 183,803 (290)

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Polysaccharide-conjugate vaccines for Burkholderia pseudomallei based on the O-antigens of serotypes A and B

Carbohydrate Polymer Technologies and Applications
Burkholderia pseudomallei, a facultative intracellular pathogen, has been classified into three distinct serotypes: A, B, and B2. Serotype A is the most prevalent, serotype B is the next most common. However, no vaccines target B.
Jingmin Yan, Jinzhu Huang, Xiaoxue Lu, Xiaoyi He, Chenglong Rao, Dongqi Nan, Haiyang Lu, Linming Guo, Qian Li, Shiwei Wang, Xuhu Mao, Xiancai Rao   +11 more
doaj  

Immunochemistry of Salmonella O-Antigens: Preparation of an Octasaccharide-Bovine Serum Albumin Immunogen Representative of Salmonella Serogroup B O-Antigen and Characterization of the Antibody Response [PDF]

, 1978
Stefan B. Svenson, Alf A. Lindberg
openalex   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

Structure and genetics of Escherichia coli O antigens. [PDF]

FEMS Microbiol Rev, 2020
Liu B, Furevi A, Perepelov AV, Guo X, Cao H, Wang Q, Reeves PR, Knirel YA, Wang L, Widmalm G.   +9 more
europepmc   +1 more source

Chemical analysis of bacterial polysaccharides. I. Studies on the monosaccharide constituents of the specific polysaccharide of O antigens of Salmonella anatum (Group E1)

, 1955
Teiichi SASAKI
openalex   +2 more sources

Evidence for O antigens as the antigenic determinants in "ribosomal" vaccines prepared from Salmonella [PDF]

, 1975
T K Eisenstein
openalex   +1 more source

Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren, Moana Busch, Pedro A. Ruiz, Ermanno Malagola, Valeria Baumeler, Federica Foti, Adelina Gross, Tobias Grütter, Hendrik Edel, Cordelia Schuler, Kristina Handler, Glenn De Lange, Isabelle C. Arnold, Cheryl de Vallière, Klaus Seuwen, Martin Hausmann, Gerhard Rogler   +16 more
wiley   +1 more source

Lipopolysaccharide O-antigens-bacterial glycans made to measure. [PDF]

J Biol Chem, 2020
Whitfield C, Williams DM, Kelly SD.
europepmc   +1 more source

Lysogenic Conversion of O Antigen 34 in Group E Salmonella (II)

, 1957
Akihisa Nakagawa
openalex   +2 more sources