Results 11 to 20 of about 451,240 (331)

Salmonella Typhimurium derived OMV nanoparticle displaying mixed heterologous O-antigens confers immunogenicity and protection against STEC infections in mice [PDF]

Microbial Cell Factories
Shiga toxin-producing Escherichia coli (STEC) is one of the major pathogens responsible for severe foodborne infections, and the common serotypes include E. coli O157, O26, O45, O103, O111, O121, and O145.
Xiaoping Bian, Yaolin Chen, Wenjin Zhang, Xinyu Liu, Meihong Lei, Haoxiang Yuan, Mengru Li, Qing Liu, Qingke Kong   +8 more
doaj   +4 more sources

Outer membrane protein size and LPS O-antigen define protective antibody targeting to the Salmonella surface [PDF]

Nature Communications, 2020
The O-antigen of LPS is known to limit the binding of antibody to bacterial surface antigens. Here the AUs show that the chemical and physical structure of the O-antigen are central factors in limiting the exposure of surface antigens to antibodies ...
C. Coral Domínguez-Medina, Marisol Pérez-Toledo, Anna E. Schager, Jennifer L. Marshall, Charlotte N. Cook, Saeeda Bobat, Hyea Hwang, Byeong Jae Chun, Erin Logan, Jack A. Bryant, Will M. Channell, Faye C. Morris, Sian E. Jossi, Areej Alshayea, Amanda E. Rossiter, Paul A. Barrow, William G. Horsnell, Calman A. MacLennan, Ian R. Henderson, Jeremy H. Lakey, James C. Gumbart, Constantino López-Macías, Vassiliy N. Bavro, Adam F. Cunningham   +23 more
doaj   +2 more sources

Systems Biology and Pangenome of Salmonella O-Antigens. [PDF]

mBio, 2019
O-antigens are glycopolymers in lipopolysaccharides expressed on the cell surface of Gram-negative bacteria. Variability in the O-antigen structure constitutes the basis for the establishment of the serotyping schema. We pursued a two-pronged approach to
Seif Y, Monk JM, Machado H, Kavvas E, Palsson BO.   +4 more
europepmc   +4 more sources

Genetics and evolution of the Salmonella galactose-initiated set of o antigens. [PDF]

PLoS ONE, 2013
This paper covers eight Salmonella serogroups, that are defined by O antigens with related structures and gene clusters. They include the serovars that are now most frequently isolated.
Peter R Reeves, Monica M Cunneen, Bin Liu, Lei Wang   +3 more
doaj   +2 more sources

Characterization of Enzyme-Linked Immunosorbent Assay (ELISA) for Quantification of Antibodies against Salmonella Typhimurium and Salmonella Enteritidis O-Antigens in Human Sera. [PDF]

BioTech (Basel), 2023
Aruta MG, Lari E, De Simone D, Semplici B, Semplici C, Dale H, Chirwa E, Kadwala I, Mbewe M, Banda H, Iturriza-Gomara M, Gordon M, Nyirenda T, Piu P, Pizza M, Berlanda Scorza F, Grappi S, Canals R, Rossi O, On Behalf Of The Vacc-iNTS Consortium Collaborators.   +19 more
europepmc   +3 more sources

Tumor-associated Tn and STn antigens: from molecular mechanism to precision diagnosis and treatment [PDF]

Frontiers in Immunology
BackgroundAbnormal protein glycosylation is a key feature of tumors. Among the modifications, Tn antigen (GalNAcα1-Ser/Thr) and its sialylated derivative, STn antigen (Neu5Acα2-6GalNAcα1-O-Ser/Thr), are prominent tumor-associated carbohydrate antigens ...
Shuailong Zhao, Cegang Fu, Boya Gong, Hongyan Wu, Ruitao Zhang, Huili Cai, Haidan Chen, Haidan Chen   +7 more
doaj   +2 more sources

Immunogenicity evaluation of altSonflex1-2–3 Shigella vaccine across mice, rats, and rabbits to inform human translational insights [PDF]

Frontiers in Immunology
Shigella, a leading cause of bacillary dysentery, represents a significant global health challenge, particularly in low- and middle-income countries. Shigellosis predominantly affects children under the age of five and is associated with high morbidity ...
Valentina Caradonna, Renzo Alfini, Marika Pinto, Roberta Di Benedetto, Carlo Giannelli, Donata Medaglini, Elena Pettini, Miren Iturriza, Omar Rossi, Francesca Micoli, Francesca Mancini   +10 more
doaj   +2 more sources

Immunochemical aspects of Hafnia alvei O antigens [PDF]

FEMS Immunology and Medical Microbiology, 2000
In the article the composition and structure of the O-specific polysaccharide chains and core region of the O antigens isolated from over 20 H. alvei strains is overviewed. Moreover, the correlation between the structure and immunospecificity of the O antigens is presented and discussed.
E Romanowska
openalex   +3 more sources

Identification of Salmonella O antigens by coagglutination [PDF]

Journal of Clinical Microbiology, 1984
This study concerns the preparation of reagents for identifying the somatic O antigens of Salmonella enteritidis. Coagglutination reagents (COAGs) with antibody fixed to killed and stabilized protein A-bearing staphylococci were prepared with antisera which were used for identifying the somatic O antigens of S.
Jay O. Cohen, L. E. Britt, William K. Harrell   +2 more
openalex   +3 more sources

Shigella Flexneri Serotypes: O-antigen Structure, Serotype Conversion, and Serotyping Methods

Oman Medical Journal, 2023
Shigella flexneri is the most common cause of shigellosis in developing countries. Up to now, 23 serotypes of S. flexneri have been reported. Different serotypes result from the addition of acetyl, glucosyl, or phosphatidylethanolamine groups on the O ...
Mehrzad Sadredinamin, Sajjad Yazdansetad, Masoud Alebouyeh, Mohammad Mahdi Karimi Yazdi, Zohreh Ghalavand   +4 more
doaj   +1 more source