The O-antigen of LPS is known to limit the binding of antibody to bacterial surface antigens. Here the AUs show that the chemical and physical structure of the O-antigen are central factors in limiting the exposure of surface antigens to antibodies ...
C. Coral Domínguez-Medina +23 more
doaj +1 more source
Questioning universal use of O– red blood cells in intrauterine transfusions
In the setting of maternal alloimmunization to antigen(s) on fetal red blood cells, significant fetal anemia may develop, and an intrauterine transfusion may be required. When selecting a blood product for intrauterine transfusion, the priority should be
Olivia G. Johnson, BS +1 more
doaj +1 more source
To respond or not to respond - a personal perspective of intestinal tolerance [PDF]
For many years, the intestine was one of the poor relations of the immunology world, being a realm inhabited mostly by specialists and those interested in unusual phenomena.
A Besredka +142 more
core +1 more source
Background New candidate protective antigens for tick vaccine development may be identified by selecting and testing antigen candidates that play key biological functions.
Ricardo Pérez-Sánchez +3 more
doaj +1 more source
The identification of novel immunogenic antigens as potential Shigella vaccine components
Background Shigella is a major diarrheal pathogen for which there is presently no vaccine. Whole genome sequencing provides the ability to predict and derive novel antigens for use as vaccines.
Ruklanthi de Alwis +9 more
doaj +1 more source
Development of a Potent Stabilizer for Long-Term Storage of Foot-and-Mouth Disease Vaccine Antigens
A local virus isolate, O/SKR/JC/2014 (O JC), has been considered as a candidate vaccine strain in the development of a domestic foot-and-mouth disease (FMD) vaccine in Korea.
Ah-Young Kim +7 more
doaj +1 more source
Deficiency of RgpG causes major defects in cell division and biofilm formation, and deficiency of LytR-CpsAPsr family proteins leads to accumulation of cell wall antigens in culture medium by Streptococcus mutans [PDF]
Streptococcus mutans is known to possess rhamnose-glucose polysaccharide (RGP), a major cell wall antigen. S. mutans strains deficient in rgpG , encoding the first enzyme of the RGP biosynthesis
Beatty, Wandy L +6 more
core +2 more sources
Preparation of human monoclonal anti-C cell line from peripheral blood B lymphocytes of D--donor
Objective To establish human hybridoma cell lines, secreting monoclonal antibody against antigens of Rh blood system, from a donor with rare D--phenotype.
Zhonghui GUO +9 more
doaj +1 more source
Structural Studies of Shigella flexneri O-Antigens [PDF]
The structures of the O-antigens of all known serotypes and subserotypes of Shigella flexneri have been reinvestigated. The results support the assumption that these antigens are composed of a basic tetrasaccharide repeating unit (1), to which alpha-D-glucopyranosyl and/or O-acetyl groups are attached at different positions. Leads to 3)-beta-D-GlcNAcp-(
L, Kenne +4 more
openaire +2 more sources
Role of early viral surface antigens in cellular immune response to vaccinia virus [PDF]
Infection of mice with the vaccinia virus strain WR, Elstree or DIs, a conditional lethal mutant of vaccinia virus, resulted in the generation of vaccinia virus-specific sensitized cytolytic T lymphocytes (CTL).
Ertl, H., Koszinowski, Ulrich H.
core +1 more source

