Results 21 to 30 of about 183,803 (290)

Is indirect coombs test by pooled cells sufficient for antibody screening? An eye-opening case series

open access: yesGlobal Journal of Transfusion Medicine, 2023
The ideal way to screen for the presence of alloantibodies is by antibody screening panels which represent all clinically significant antigens in appropriate dosage.
P Sriraman   +5 more
doaj   +1 more source

Role of O-Acetylation in the Immunogenicity of Bacterial Polysaccharide Vaccines

open access: yesMolecules, 2018
The incidence of infectious diseases caused by several bacterial pathogens such as Haemophilus influenzae type b, Streptococcus pneumoniae, and Neisseria meningitidis, has been dramatically reduced over the last 25 years through the use of glycoconjugate
Francesco Berti   +2 more
doaj   +1 more source

In silico selection of functionally important proteins from the mialome of Ornithodoros erraticus ticks and assessment of their protective efficacy as vaccine targets

open access: yesParasites & Vectors, 2019
Background New candidate protective antigens for tick vaccine development may be identified by selecting and testing antigen candidates that play key biological functions.
Ricardo Pérez-Sánchez   +3 more
doaj   +1 more source

Outer membrane protein size and LPS O-antigen define protective antibody targeting to the Salmonella surface

open access: yesNature Communications, 2020
The O-antigen of LPS is known to limit the binding of antibody to bacterial surface antigens. Here the AUs show that the chemical and physical structure of the O-antigen are central factors in limiting the exposure of surface antigens to antibodies ...
C. Coral Domínguez-Medina   +23 more
doaj   +1 more source

Development of a Potent Stabilizer for Long-Term Storage of Foot-and-Mouth Disease Vaccine Antigens

open access: yesVaccines, 2021
A local virus isolate, O/SKR/JC/2014 (O JC), has been considered as a candidate vaccine strain in the development of a domestic foot-and-mouth disease (FMD) vaccine in Korea.
Ah-Young Kim   +7 more
doaj   +1 more source

Preparation of human monoclonal anti-C cell line from peripheral blood B lymphocytes of D--donor

open access: yesZhongguo shuxue zazhi, 2022
Objective To establish human hybridoma cell lines, secreting monoclonal antibody against antigens of Rh blood system, from a donor with rare D--phenotype.
Zhonghui GUO   +9 more
doaj   +1 more source

The identification of novel immunogenic antigens as potential Shigella vaccine components

open access: yesGenome Medicine, 2021
Background Shigella is a major diarrheal pathogen for which there is presently no vaccine. Whole genome sequencing provides the ability to predict and derive novel antigens for use as vaccines.
Ruklanthi de Alwis   +9 more
doaj   +1 more source

In Planta Production of the Receptor-Binding Domain From SARS-CoV-2 With Human Blood Group A Glycan Structures

open access: yesFrontiers in Chemistry, 2022
Glycosylation of viral envelope proteins is important for infectivity and immune evasion. The SARS-CoV-2 spike protein is heavily glycosylated and host-derived glycan modifications contribute to the formation of specific immunogenic epitopes, enhance the
Julia König-Beihammer   +11 more
doaj   +1 more source

The (Sialyl) Tn antigen: Contributions to immunosuppression in gastrointestinal cancers

open access: yesFrontiers in Oncology, 2023
Cellular signaling pathways are intricately regulated to maintain homeostasis. During cancer progression, these mechanisms are manipulated to become harmful. O-glycosylation, a crucial post-translational modification, is one such pathway that can lead to
Christabelle Rajesh   +1 more
doaj   +1 more source

A Sweet Warning: Mucin-Type O-Glycans in Cancer

open access: yesCells, 2022
Glycosylation is a common post-translational modification process of proteins. Mucin-type O-glycosylation is an O-glycosylation that starts from protein serine/threonine residues.
Yuhan Zhang   +6 more
doaj   +1 more source

Home - About - Disclaimer - Privacy