Results 71 to 80 of about 2,244 (165)

Ciglitazone-a human PPARγ agonist-disrupts dorsoventral patterning in zebrafish. [PDF]

, 2019
Peroxisome proliferator-activated receptor γ (PPARγ) is a ligand-activated transcription factor that regulates lipid/glucose homeostasis and adipocyte differentiation.
Cheng, Vanessa, Dasgupta, Subham, Reddam, Aalekhya, Volz, David C   +3 more
core  

In pancreatic ductal adenocarcinoma blood concentrations of some organochlorine compounds and coffee intake are independently associated with KRAS mutations [PDF]

, 2009
8 pages, 4 pages.-- PMID: 19797353 [PubMed].-- Printed version published Nov 2009.While KRAS activation is a fundamental initiating event in the aetiopathogenesis of pancreatic ductal adenocarcinoma (PDA), environmental factors influencing the occurrence
Crous Bou, Marta, Grimalt, Joan O., Jariod, Manuel, Malats, Núria, Marco Asensio, Esther, Porta, Miquel, Pumarega, José, Real, Francisco X., Rifà, Juli   +8 more
core   +1 more source

Exposure to 4,4′‐DDE in visceral adipose tissue and weight loss in adolescents from the Teen‐LABS cohort

Obesity, Volume 32, Issue 5, Page 1023-1032, May 2024.
Abstract Objective Dichlorodiphenyldichloroethylene (DDE), an obesogen accumulating in adipose tissue, is released into circulation with weight loss, although its impact is underexplored among adolescents. We tested the association using an integrative translational approach of epidemiological analysis among adolescents with obesity and in vitro ...
Bruna Rubbo, Zhenjiang Li, Phum Tachachartvanich, Brittney O. Baumert, Hongxu Wang, Shudi Pan, Sarah Rock, Justin R. Ryder, Todd Jenkins, Stephanie Sisley, Xiangping Lin, Scott Bartell, Thomas H. Inge, Stavra Xanthakos, Brooklynn McNeil, Anna R. Robuck, Michele A. La Merrill, Douglas I. Walker, David V. Conti, Rob McConnell, Sandrah P. Eckel, Lida Chatzi   +21 more
wiley   +1 more source

Understanding the role of endocrine disrupting chemicals as environmental obesogens in the obesity epidemic: A comprehensive overview of epidemiological studies between 2014 and 2024

Ecotoxicology and Environmental Safety
The prevalence of obesity has reached epidemic proportions worldwide, posing a significant public health concern due to its association with various chronic diseases and healthcare costs.
Marta Jaskulak, Malwina Zimowska, Marta Rolbiecka, Katarzyna Zorena   +3 more
doaj   +1 more source

Updates in Medical and Surgical Weight Loss

Journal of Midwifery &Women's Health, Volume 69, Issue 3, Page 414-421, May/June 2024.
Abstract The number of individuals with obesity is at an all‐time high, and the rate of obesity continues to climb each year. Obesity is a chronic disease with widespread effects throughout the body. Midwives and perinatal care providers need an understanding of the etiology, pathophysiology, and interventions for obesity.
Melissa G. Davis, Bethany D. Sanders
wiley   +1 more source

Obesogenic environments as major determinants of a disease: It is time to re‐shape our cities

Diabetes/Metabolism Research and Reviews, Volume 40, Issue 1, January 2024.
Abstract Obesity rates are increasing in almost all high‐ and low‐income countries, and population‐based approaches are necessary to reverse this trend. The current global efforts are focused on identifying the root causes of obesity and developing effective methods for early diagnosis, screening, treatment, and long‐term management, both at an ...
Ludovica Verde, Luigi Barrea, Jacqueline Bowman‐Busato, Volkan Demirhan Yumuk, Annamaria Colao, Giovanna Muscogiuri   +5 more
wiley   +1 more source

Perfluoroalkylated substances effects in Xenopus laevis A6 kidney epithelial cells determined by ATR-FTIR spectroscopy and chemometric analysis [PDF]

, 2016
The effects of four perfluoroalkylated substances (PFASs), namely, perfluorobutanesulfonate (PFBS), perfluorooctanoic acid (PFOA), perfluorooctanesulfonate (PFOS) and perfluorononanoic acid (PFNA) were assessed in Xenopus laevis A6 kidney epithelial ...
Gorrochategui, Eva, Lacorte, Silvia, Martin, Francis L, Tauler, Roma   +3 more
core   +3 more sources

Update of the risk assessment of polybrominated diphenyl ethers (PBDEs) in food

EFSA Journal, Volume 22, Issue 1, January 2024.
Abstract The European Commission asked EFSA to update its 2011 risk assessment on polybrominated diphenyl ethers (PBDEs) in food, focusing on 10 congeners: BDE‐28, ‐47, ‐49, ‐99, ‐100, ‐138, ‐153, ‐154, ‐183 and ‑209. The CONTAM Panel concluded that the neurodevelopmental effects on behaviour and reproductive/developmental effects are the critical ...
EFSA Panel on Contaminants in the Food Chain (CONTAM), Dieter Schrenk, Margherita Bignami, Laurent Bodin, James Kevin Chipman, Jesús del Mazo, Bettina Grasl‐Kraupp, Christer Hogstrand, Laurentius (Ron) Hoogenboom, Jean‐Charles Leblanc, Carlo Stefano Nebbia, Elsa Nielsen, Evangelia Ntzani, Annette Petersen, Salomon Sand, Tanja Schwerdtle, Heather Wallace, Diane Benford, Peter Fürst, Andy Hart, Martin Rose, Henri Schroeder, Martine Vrijheid, Sofia Ioannidou, Marina Nikolič, Luisa Ramos Bordajandi, Christiane Vleminckx   +26 more
wiley   +1 more source

Potentilla rugulosa Nakai Extract Attenuates Bisphenol A-, S- and F-Induced ROS Production and Differentiation of 3T3-L1 Preadipocytes in the Absence of Dexamethasone

Antioxidants, 2020
Endocrine disrupting chemicals (EDCs) disrupt the physiological metabolism, thus playing an important role in the development of obesity. EDCs, the so-called ‘obesogens’, might predispose some individuals to gain weight.
Sun-Il Choi, Jong Seok Lee, Sarah Lee, Wan-Sup Sim, Young-Cheul Kim, Ok-Hwan Lee   +5 more
doaj   +1 more source

Liver transcriptome analysis of Atlantic cod (Gadus morhua) exposed to PCB 153 indicates effects on cell cycle regulation and lipid metabolism [PDF]

, 2014
Background: Polychlorinated biphenyls (PCBs) are persistent organic pollutants (POPs) with harmful effects in animals and humans. Although PCB 153 is one of the most abundant among PCBs detected in animal tissues, its mechanism of toxicity is not well ...
Anders Goksøyr, Christer Hogstrand, Fekadu Yadetie, Marta Eide, Odd Karlsen   +4 more
core   +1 more source