Results 71 to 80 of about 622 (115)

A survey of the antidote preparedness in Norwegian hospitals. [PDF]

Eur J Hosp Pharm, 2022
Lao YE, Goffeng A, Spillum BJ, Jacobsen D, Nakstad ER, Hovda KE.   +5 more
europepmc   +1 more source

The present approaches to the development of prophylactic and therapeutic antidotes against nerve agents [PDF]

A. Saxena, B. Doctor, B. Doctor, F. Ekström, G. Ellman, G. Lallement, J. Bajgar, J. Bajgar, J. Bajgar, J. Bajgar, J. Clement, J. Fusek, J. Fusek, J. Gordon, J. Kassa, J. Kassa, J. Patocka, Jana Karasová, Jiří Bajgar, Jiří Kassa, K. Kuca, K. Kuca, K. Kuca, K. Kuca, K. Musilek, K. Musilek, K. Musilek, K. Musilek, Kamil Kuča, Kamil Musílek, L. Sevelova, R. Gordon, R. Tallarida, V. Dohnal   +33 more
core   +2 more sources

Modelling organophosphate intoxication in C. elegans highlights nicotinic acetylcholine receptor determinants that mitigate poisoning. [PDF]

PLoS One, 2023
Izquierdo PG, Charvet CL, Neveu C, Green AC, Tattersall JEH, Holden-Dye L, O'Connor V.   +6 more
europepmc   +1 more source

Nanodiamond mediated delivery of pyridinium oxime antidotes to central nervous system for potential treatment of exposure to nerve agents. [PDF]

Chem Biol Interact
Bondar D, Smirnova O, Nagappa NM, Heinmaa I, Soukup O, Kobrlova T, Opravil J, Hrabinova M, Jun D, Starkov P, Spuul P, Kuča K, Mochalin VN, Karpichev Y.   +13 more
europepmc   +1 more source

Click-chemistry-derived oxime library reveals efficient reactivators of nerve agent-inhibited butyrylcholinesterase suitable for pseudo-catalytic bioscavenging. [PDF]

Arch Toxicol
Čadež T, Maček Hrvat N, Šinko G, Kalisiak J, Radić Z, Fokin VV, Sharpless KB, Taylor P, Kovarik Z.   +8 more
europepmc   +1 more source

The oxime HI-6 : Determination of the pharmacokinetics and the effect of atropine co-administration in guinea pigs and domestic swine [PDF]

Chemical warfare agents including organophosphorus nerve agents (NA) continue to be a significant threat to both military and civilian populations. The current Canadian Armed Forces (CAF) treatment of NA poisoning includes administration of the oxime HI-
Bohnert, Sara
core  

Experimental and translational models of Alzheimer's disease: From neurodegeneration to novel therapeutic insights. [PDF]

J Prev Alzheimers Dis
Khan N, De S, Boddu S, Pravala N.
europepmc   +1 more source

Synthesis, in vitro screening and molecular docking of isoquinolinium-5-carbaldoximes as acetylcholinesterase and butyrylcholinesterase reactivators. [PDF]

J Enzyme Inhib Med Chem, 2020
Malinak D, Dolezal R, Dolezal R, Hepnarova V, Hozova M, Andrys R, Bzonek P, Racakova V, Korabecny J, Gorecki L, Mezeiova E, Psotka M, Jun D, Kuca K, Musilek K.   +14 more
europepmc   +1 more source

A-series agent A-234: initial in vitro and in vivo characterization. [PDF]

Arch Toxicol
Hrabinova M, Pejchal J, Hepnarova V, Muckova L, Junova L, Opravil J, Zdarova Karasova J, Rozsypal T, Dlabkova A, Rehulkova H, Kucera T, Vecera Z, Caisberger F, Schmidt M, Soukup O, Jun D.   +15 more
europepmc   +1 more source

Screening of efficient salicylaldoxime reactivators for DFP and paraoxon-inhibited acetylcholinesterase. [PDF]

RSC Med Chem
Wei Z, Zhang D, Liu X, Nie H, Ouyang Q, Zhang X, Zheng Z.   +6 more
europepmc   +1 more source