Results 121 to 130 of about 1,662,166 (403)

The Jurisdiction Argument for Immigration Control [PDF]

open access: yes, 2016
Jurisdictionism offers a new rationale for restricting immigration. Immigrants impose new obligations on the people whose territories they enter. Insofar as these obligations are unwanted, polities are justified in turning immigrants away, so long as the
Lamey, Andy
core  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

LEGAL ISSUES OF LIABILITY OF HOMEOWNERS

open access: yesГуманитарные и юридические исследования, 2021
Activities of such a modern civil legal form of apartment building management, as association of homeowners has not only advantages, but also involves liability according to the legislation of the Russian Federation.
Vera Grigorievna Fedorova   +1 more
doaj  

Transformational Leadership and Voice: When Does Felt Obligation to the Leader Matter?

open access: yesJournal of business and psychology, 2021
Jinyun Duan   +3 more
semanticscholar   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Extraterritorial Obligations and the Obligation to Protect

open access: yes, 2017
Since the late 1970s, what we today label ‘globalisation’ has altered many aspects of international law, not least international human rights law. This has been reflected inter alia in increased calls for universal respect for human rights beyond a state’s territorial border.
openaire   +2 more sources

Democracy and rule of law: the Hungarian goulash [PDF]

open access: yes, 2013
The article discusses the Tavares Report on the new constitutional changes in Hungary, the implications of the new Constitution on Hungary's obligation under the Treaty, on European Union, especially its continuing commitment to the Union founding ...
Ressel, James
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Is the Duty to Prevent Genocide an Obligation of Result or an Obligation of Conduct according to the ICJ? (blogpost) [PDF]

open access: yes, 2019
This post analyses the duty to prevent genocide embodied in the 1948 UN Genocide Convention as described by the International Court of Justice in the Bosnia v. Serbia case.
Longobardo, M., Longobardo, M.
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

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