Results 121 to 130 of about 99,866 (311)

Relationship between oxidative balance score and post-stroke depression: insights from the NHANES 2005–2018 cross-sectional study

open access: yesFrontiers in Neurology
IntroductionThe Oxidative Balance Score (OBS) represents an integrated measure of oxidative-reductive homeostasis. Despite the established role of oxidative stress in the development of post-stroke depression (PSD), the association between OBS and PSD in
Hai-Jun Li   +4 more
doaj   +1 more source

MAGI3 Acts as an Intestinal Epithelial Gatekeeper in Inflammation‐Associated Colorectal Cancer by Suppressing the STAT3‐CCL2 Axis and TAM‐Mediated Immunosuppression

open access: yesAdvanced Science, EarlyView.
Our study identifies MAGI3 as an intestinal epithelial gatekeeper that restrains inflammation‐associated colorectal tumorigenesis but is itself suppressed under highly inflammatory conditions. MAGI3 deficiency activates the STAT3‐CCL2 signaling, thereby promoting TAM‐mediated immunosuppression and inflammation‐associated colorectal tumor progression ...
Yumeng Yang   +12 more
wiley   +1 more source

Association between oxidative balance score and 10-year atherosclerotic cardiovascular disease risk: results from the NHANES database

open access: yesFrontiers in Nutrition
IntroductionThe oxidative balance score (OBS) is a holistic measure that represents the overall equilibrium between prooxidants and antioxidants in one’s diet and lifestyle.
Dekui Jin   +7 more
doaj   +1 more source

CKMT1 Counteracts VDAC1 Oligomerization‐Induced Neuronal Pyroptosis Through Steric Hindrance in Ischemic Stroke

open access: yesAdvanced Science, EarlyView.
CKMT1 inhibits VDAC1 oligomerization via a dual‐region mechanism: its NTD interacts with the VDAC1 C‐terminal domain, while residues 1–39 sterically hinder dimerization, thereby reducing mtDNA leakage and AIM2 inflammasome activation, suppressing neuronal pyroptosis and protecting against cerebral ischemic injury. ABSTRACT Ischemic stroke is one of the
Xiaoyu Wang   +17 more
wiley   +1 more source

Design and Control of Node Architecture in OBS Optical Network

open access: yes, 2011
In this paper, we analyse the optical burst switched (OBS) network, discuss the OBS node architecture. In OBS network, to construct a good data structure is very important. The OBS incoming data are assembled into basic units, referred to as data bursts,
Ning Zhang, Mao Chang Ge
core   +1 more source

Treatment of Heavy Postmenopausal Bleeding With Comorbidities in Septuagenarian, Octogenarian and Nonagenarian (Case Series)

open access: yesPakistan Armed Forces Medical Journal
Few postmenopausal patients with a history of postmenopausal bleeding with comorbidities and unfit for general anaesthesia.These could not be treated with conservative treatments and developed moderate to severe anaemia.
Mamuna Qayum   +5 more
doaj   +1 more source

AI‐Assisted Ultrasensitive Biosensing using Metal‐Electrolyte‐Metal‐Insulator‐Silicon Structure Based on Oxygen‐Tunable Iridium Oxide Nanonets for Lysyl‐Oxidase‐Like‐2 Breast Cancer Detection

open access: yesAdvanced Electronic Materials, EarlyView.
An oxygen‐controlled iridium‐oxide (IrOx) nano‐net structure is developed to enhance the sensitivity of metal‐electrolyte‐metal‐insulator‐silicon (MEMIS) biosensors. Integrated with a deep learning model, this platform achieves a high accuracy of 94.8% for detecting the breast cancer biomarker LOXL2.
Chiao‐Fan Chiu   +9 more
wiley   +1 more source

Virtual topology design for OBS optical networks

open access: yes, 2007
Burst loss and delay are two main issues in optical burst switching (OBS) networks. In OBS, if the hop-count between the source-destination node pair can be reduced, both the control packet and the corresponding data burst will suffer less risk of ...
B. Wu, Yeung, KL, K. L. Yeung, Wu, B
core   +1 more source

Effectiveness of myoinositol versus metformin as adjuvant treatment on infertile PCOS women undergoing ovulation induction cycles prospective cohort study

open access: yesJournal of Medicine in Scientific Research
Background In anovulatory infertility Polycystic ovary syndrome (PCOS) plays a leading role, characterized by endocrine and metabolic disturbances. While metformin is usually used to decrease insulin resistance and restore ovulation, myoinositol has ...
Ahmed M. Salman   +2 more
doaj   +1 more source

Disproportionate Environmental Risks: A Descriptive Analysis of Chemical Facilities and Accidents in the United States

open access: yesApplied Economic Perspectives and Policy, EarlyView.
ABSTRACT Using nationwide data on the US Environmental Protection Agency's Risk Management Plan (RMP) program, we examine the proportions of underserved populations living near facilities that use extremely hazardous chemicals, both before and after accidents involving fires, explosions, and/or toxic vapors occur.
Karlee Cook   +3 more
wiley   +1 more source

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