Results 111 to 120 of about 4,109,796 (295)

Desarrollo de la Autonomía del Alumnado de Primaria en Educación Física a través de un proceso de investigación-acción. [Development of Autonomy of Elementary Students in Physical Education through a process of action research].

open access: yesRevista Internacional de Ciencias del Deporte, 2015
Partiendo del enfoque competencial del sistema educativo, y considerando que una de las competencias en la etapa de educación primaria está relacionada con la autonomía e iniciativa personal, los objetivos que se plantean en este estudio son (a) desvelar
Francisco Jiménez-Jiménez   +1 more
doaj   +1 more source

Observing Neurodiversity, Observing Methodology: Ethnography in Pandemic Times

open access: yesInternational Journal of Qualitative Methods
Ethnographic researchers have long relied upon observation as a powerful means to learn about social relations. This paper discusses research observation that was conducted as a part of an institutional ethnography (IE) investigating how people use the language and ideas of neurodiversity across different settings. While our research protocol initially
Margaret F. Gibson   +5 more
openaire   +2 more sources

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Enhancing the Assessment of Verbal Aggression Through Observational Methodology

open access: yes, 2011
The assessment of verbal aggression in adolescent and young adult dating relationships has largely relied on self-report methodology. We investigated whether information on verbal aggression derived from an observational assessment would enhance the ...
Katherine M. Klipfel   +2 more
core   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

A methodology for teaching observational skills to staff nurses

open access: yes, 1991
A two-group experimental design was used to determine if the Observation Schema (OS) teaching methodology would make a difference in observational skills of 60 registered staff nurses in a federally supported hospital for veterans. Subjects were randomly
Wilson, Paulette
core   +4 more sources

A Methodology for Effective Metadata Design in Earth Observation

open access: yes, 2017
The satellite images have become an essential source of information to address and analyze environmental issues quickly, repeatedly and in a reliable way. The increasing number of remotely sensed images are the first impediments for data discovery, access and processing.
Desconnets, Jean-Christophe   +2 more
openaire   +2 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Blending Observational Methods: Possibilities, Strategies, and Challenges

open access: yes, 2008
Qualitative researchers have used the observational strategies of video recording and participant observation to investigate specific phenomena. Although there have been recent advances in the separate use of these strategies, there is evidence that ...
Bottorff, Joan L.   +2 more
core   +1 more source

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