Results 71 to 80 of about 747,238 (298)

Probing the time dependence of dark energy

open access: yes, 2011
A new method to investigate a possible time-dependence of the dark energy equation of state $w$ is proposed. We apply this methodology to two of the most recent data sets of type Ia supernova (Union2 and SDSS) and the baryon acoustic oscillation peak at $
A. Conley .   +17 more
core   +1 more source

The relationship between zinc intake and serum/plasma zinc concentration in adults: a systematic review and dose–response meta-analysis by the EURRECA Network [PDF]

open access: yes, 2012
Dietary zinc recommendations vary widely across Europe due to the heterogeneity of pproaches used by expert panels. Under the EURRECA consortium a protocol was designed to systematically review and undertake meta-analyses of research data to create a ...
Anna-Louise Stammers   +9 more
core   +2 more sources

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

THE OBSERVATION OF GENDER DIFFERENCES IN HANDBALL [La observación de diferencias de género en balonmano]

open access: yesE-balonmano.com: Revista de Ciencias del Deporte, 2018
Overcoming a superficial view regarding the gender in handball, through the identification of differences between women and men in high level competitions is the objective of this work.
Miguel Pic Aguilar
doaj   +2 more sources

Intensive Family Observations: A Methodological Guide

open access: yesSociological Methods & Research, 2020
There is a dearth of methodological guidance on how to conduct participant observation in private spaces such as family homes. Yet, participant observations can provide deep and valuable data about family processes. This article draws on two ethnographic studies of family life in which researchers conduct in-depth interviews, recruit families, and ...
Annette Lareau, Aliya Hamid Rao
openaire   +2 more sources

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Design, Validation, and Reliability of an Observational Instrument for Technical and Tactical Actions in Singles Badminton

open access: yesFrontiers in Psychology, 2020
Technical and tactical actions are decisive in terms of badminton player competitive performance. The main objective of this research was to design, validate, and estimate the reliability of an observational instrument for the analysis of the tactical ...
Gema Torres-Luque   +7 more
doaj   +1 more source

An Appraisal of Participant Observation Methodology

open access: yesAnthropology of the Middle East, 2023
Abstract All different sciences are defined in a specific way. It is not enough to define anthropology as a science that has studied human beings at all times and all places. It is the methodology of anthropology that is unique and increasingly appreciated by other fields.
openaire   +1 more source

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