Results 81 to 90 of about 65,758,577 (259)

Orexin receptor antagonists in the treatment of insomnia associated with psychiatric disorders: a systematic review

Translational Psychiatry
Insomnia is highly comorbid in patients with psychiatric disorders, including depression, bipolar disorder, and substance use disorders, and should be treated as an independent condition. Dual orexin receptor antagonists (DORAs) have been investigated as
Taro Kishi, Michinori Koebis, Michiko Sugawara, Yuka Kawatsu, Takehiro Taninaga, Nakao Iwata   +5 more
doaj   +1 more source

Sensorial changes in individuals with HTLV-1: systematic review

Revista Pesquisa em Fisioterapia, 2018
Background: Sensory function is recognized as a precursor of the movement recovery. Therefore, the symptoms presented by people with HTLV-1 can result in impairment in the performance of functional activities.
Erika Pedreira da Fonseca, Livia Aguiar Pereira, Ludmila Souza Caldas Lordelo, Rebeca Freitas Reis Nunes, Elen Batriz Carneiro Pinto   +4 more
doaj   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Results from observational studies.

, 2016
Results from observational studies.
A. Sedrakyan (2833064), H. J. L. van der Heide (2833079), J. M. T. A. Meessen (2833061), R. G. H. H. Nelissen (2833076), J. W. Schoones (2833067), M. Fiocco (2833070), B. G. Pijls (2833073)   +6 more
core   +1 more source

Topic and focus : two structural positions associated with logical functionsin the left periphery of the Hungarian sentence [PDF]

, 2008
The paper explicates the notions of topic, contrastive topic, and focus as used in the analysis of Hungarian. Based on distributional criteria, topic and focus are claimed to represent distinct structural positions in the left periphery of the Hungarian ...
Kiss, Katalin, Kiss, Katalin E., Katalin Kiss   +2 more
core   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Results of Observational studies.

, 2016
Results of Observational studies.
Lewis Cooney (2620792), Daniel Hawcutt (2620795), Ian Sinha (91102)   +2 more
core   +1 more source

Health risk behaviours, mental health and HbA1c: an overview of reviews of observational studies

BMJ Open
Objectives To implement an overview of reviews that discuss the current state of syntheses (such as systematic reviews) of only observational studies on health risk behaviours (HRBs), including smoking, alcohol intake, poor sleep, poor quality diet ...
Mark Daniel, Soumya Mazumdar, Luis Salvador-Carulla, Nasser Bagheri, Nerea Almeda, Hossein Tabatabaei Jafari, Gweneth Leigh, Diego Diaz Milanes   +7 more
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source