Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
A novel description of dynamic organ-specific trajectories in pelvic organ prolapse based on magnetic resonance imaging traces. [PDF]
Hou X +5 more
europepmc +1 more source
Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley +1 more source
The Limits of Humans in Data Gathering: Documentation Error Rates in the Electronic Health Record in the Operating Room. [PDF]
Bradley AR +4 more
europepmc +1 more source
A new framework for facial age estimation in humans and AIs. [PDF]
Ganel T, Mazuz Y, Algom D, Goodale MA.
europepmc +1 more source
Historical records in solar physics. [PDF]
Chatzistergos T.
europepmc +1 more source
Impact of MRI slice thickness and fiducial marker orientation on geometric accuracy in multi-echo GRE imaging for prostate radiotherapy planning. [PDF]
Hayashi A +6 more
europepmc +1 more source
Event-triggered model predictive control with high-gain disturbance observers for cooperative control of virtual coupling trains in metros. [PDF]
Zuo J, Xue M, Zeng Y, Xu M, Lin J.
europepmc +1 more source
The neurodiversity movement vs. the medical model of autism. [PDF]
Kapp SK.
europepmc +1 more source

