Results 61 to 70 of about 6,856,972 (296)

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Dissecting and validation the biomarker of heart failure progression in patients with atherosclerosis by single-cell sequencing, bioinformatics, and machine learning

open access: yesFrontiers in Genetics
ObjectiveThis study aimed to identify early biomarkers associated with the progression from atherosclerosis (AS) to heart failure (HF) by integrating single-cell RNA sequencing (scRNA-seq) and bulk transcriptomic data, and to explore the potential ...
Lihua Ni   +10 more
doaj   +1 more source

INJURY RISK FACTORS IN CHILDREN AND YOUTH IN PHYSICAL / SPORTS ACTIVITY

open access: yesAnnales Kinesiologiae, 2015
Purpose: The aim of the article is to define the injury risk factors in physical/sports activity and how they may correlate.  Methods: A systematic review of electronic databases MEDLINE, Google Scholar, ScienceDirect and Cinahl in May 2015 has ...
Marina Dobnik
doaj   +1 more source

Generic occurrence of rings in rotating systems

open access: yes, 2000
In rotating scattering systems, the generic saddle-center scenario leads to stable islands in phase space. Non-interacting particles whose initial conditions are defined in such islands will be trapped and form rotating rings.
Benet   +12 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Prevalence of Post-traumatic Stress Disorder Symptoms among Road Traffic Accident Victims: A Cross-sectional Study from Gujarat, India [PDF]

open access: yesJournal of Clinical and Diagnostic Research
Introduction: Road Traffic Accidents (RTAs) can develop Post-Traumatic Stress Disorder (PTSD) due to emotional trauma, which significantly affects the quality of life. Despite satisfactory psychological recovery for many RTA victims, a notable percentage
Hetal Jitendrabhai Shah   +2 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Integrating photovoice as an adjunct teaching modality in improving critical thinking disposition among Chinese nursing students in community health nursing: a mixed-methods study

open access: yesBMC Nursing
Aims This study aimed to examine the effectiveness of using Photovoice as an adjunct teaching modality to enhance critical thinking dispositions among Chinese nursing students in a community health nursing course.
Yayun Song   +4 more
doaj   +1 more source

AI Text Generators and the Truth Paradigm: Considerations from a Phenomenological Perspective

open access: yesFilozofia
NLP has opened a new level for artificial intelligence: the truth. But AI text generators do not tell the truth reliably. That creates the contradiction of a truth-seeking authority saying something untrue. The paradigm of truth seems to be under attack.
Kathrin Burghardt
doaj   +1 more source

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