Results 1 to 10 of about 2,627 (178)
Dermatology Online Journal, 2015 We present a case of exogenous ochronosis in a 53-year-old woman with skin type IV, who used a topical hydroquinone preparation of an unknown concentration for several years. Traditionally, exogenous ochronosis was thought to occur exclusively in patients with darker skin types who use high concentrations of hydroquinone cream.
Nagler, Arielle +3 more
doaj +10 more sources
Non-Insulated Microneedle Radiofrequency for the Treatment of Hydroquinone-Induced Exogenous Ochronosis: A Case Report and Literature Review. [PDF]
Clin Cosmet Investig DermatolNamthong Wittayabusarakam, Suthinee Rutnin, Natthachat Jurairattanaporn Division of Dermatology, Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, ThailandCorrespondence: Natthachat Jurairattanaporn, Division ...
Wittayabusarakam N +2 more
europepmc +2 more sources
A Dark Turn in the OR: Incidental Discovery of Ochronosis during Trauma Surgery: A Case Report. [PDF]
J Orthop Case RepIntroduction: Alkaptonuria is a rare autosomal recessive metabolic disorder caused by deficiency of homogentisic acid (HGA) oxidase, leading to the accumulation of HGA. The polymerized oxidation products of HGA in connective tissues, a condition known as
Parth K +5 more
europepmc +2 more sources
Ochronotic arthropathy: skeletal manifestations and orthopaedic treatment. [PDF]
EFORT Open RevAlkaptonuria is an extremely rare disorder of tyrosine metabolism caused by an autosomal recessive enzymatic deficiency of homogentisic acid (HGA) oxidase, causing its accumulation in collagenous structures, especially in hyaline cartilage.
Salem KH, Elmoghazy AD.
europepmc +2 more sources
Ease of sutureless aortic valve replacement in a patient with unexpected ochronosis: a case report. [PDF]
J Cardiothorac SurgBackground Alkaptonuria is a rare congenital metabolic disorder characterized by homogentisic acid accumulation in body cartilage and connective tissues due to a deficient homogentisic acid dioxygenase enzyme.
Hosseini S +5 more
europepmc +2 more sources
Ochronotic Arthropathy of the Shoulder - A Rare Case Report. [PDF]
J Orthop Case RepIntroduction: Alkaptonuria is a metabolic disorder due to accumulation of homogentisic acid, leading to destruction of major joints. Very few cases of ochronosis with shoulder involvement have been reported in literature. Case Report: We report a 31-year-
Nair AV +5 more
europepmc +2 more sources
Non-cemented Total Hip Arthroplasty in a Rare Case with Black Hip, A Case Report. [PDF]
Adv Biomed ResAlkaptonuria is a metabolic disorder characterized by homogentisic acid accumulation in connective tissue. Ochronotic arthropathy, a rare condition reported in alkaptonuria, mostly affects the knee joint.
Shayan-Moghadam R +3 more
europepmc +2 more sources
Molecular Analysis of the HGD Gene in 9 Families With Alkaptonuric Ochronosis in Iran and Identification of Two Novel Variants. [PDF]
Mol Genet Genomic MedObjectives Alkaptonuria (AKU) (MIM number 203500) or homogentisic acid oxidase deficiency is a metabolic autosomal recessive disorder caused by mutations in the homogentisate 1, 2‐dioxygenase (HGD) (MIM number 607474) gene.
Azami A +5 more
europepmc +2 more sources
Indian Journal of Dermatology, 2000 Ochronosis is a rare disorder, which presents with distinct clinical and biochemical features. A fifty seven year old male presented with fracture femur, osteoarthritis, Oslerâ€s sign, alkaptonuria and cutaneous ochronosis. Though the clinical progression of his alkaptonuria was typical, he presented interesting features including non ...
Srikumar G +5 more
openaire +2 more sources