Results 41 to 50 of about 2,076 (188)
Cardiac ochronosis: not so benign
, 2009 A 78-year-old patient with ochronosis has developed symptomatic aortic stenosis. He has undergone an aortic valve replacement that was highly complicated by a severe aortic calcification.
Mathonet, Perrine +3 more
core +1 more source
Ochronotic Chondropathy: A Case Report
Biomedicines, 2023 Endogenous ochronosis, also known as alkaptonuria, is a rare disease known for its bluish-black discoloration of the skin, sclerae, and pinnae, as well as urine that turns black upon standing.
Jake Littman +4 more
doaj +1 more source
, 2012 Alkaptonuria (AKU) is an iconic disease caused by deficiency of the enzyme homogentisate 1,2-dioxygenase (HGD). Deficiency results in an increase in the circulating concentration of homogentisic acid (HGA), which over time is deposited as pigmented ...
Taylor, Adam +4 more
core +4 more sources
International Journal of Cosmetic Science, EarlyView.A Thiamidol‐containing skincare regimen showed significant improvement in facial hyperpigmentation in a real‐world study across 11 European countries. The treatment led to a significant reduction in mMASI scores, enhanced overall skin condition and demonstrated high tolerability.
B. Schuster +12 more
wiley +1 more source
Metabolites, 2022 Changes in the phenylalanine (PHE)/tyrosine (TYR) pathway metabolites before and during homogentisic acid (HGA)-lowering by nitisinone in the Suitability of Nitisinone in Alkaptonuria (AKU) 2 (SONIA 2) study enabled the magnitude of the flux in the ...
Lakshminarayan R. Ranganath +10 more
doaj +1 more source
Journal of the American Academy of Dermatology, 2000 Ochronosis is an uncommon condition characterized by yellow-brown pigment deposits in the dermis. It occurs in exogenous and endogenous forms. We report a case of exogenous ochronosis in a Hispanic woman and discuss the different forms of this condition. We treated the lesions with Q-switched ruby laser.
K E, Kramer +3 more
openaire +2 more sources
International Journal of Dermatology, EarlyView.Delphi‐based expert consensus for diagnosis and management of common hyperpigmentation disorders in Indian dermatology practice, integrating evidence review, iterative voting, and consensus‐driven recommendations. ABSTRACT Hyperpigmentation disorders are prevalent in individuals with skin of color and are associated with considerable psychosocial ...
Rashmi Sarkar +12 more
wiley +1 more source
Exogenous ochronosis: the failure of depigmenting creams [PDF]
, 2019 Exogenous ochronosis (EO) is an entity that manifests as black-bluish or grayish-brown cutaneous hyperpigmentation, which is a consequence of the deposition of ochronotic pigment with characteristic banana-like morphology between the collagen fibers of ...
Sánchez-Martínez, Eva María +5 more
core +1 more source
Autopsy and Case Reports, 2021 Ochronosis is a cutaneous disorder caused by the accumulation of phenols, either endogenously as homogentisic acid in patients with alkaptonuria (autosomal recessive disorder with deficiency of the enzyme homogentisic acid oxidase), or exogenously in ...
Amir Qorbani +4 more
doaj
Actinic granuloma-like change in exogenous ochronosis: Case report
, 1990 Exogenous ochronosis is caused by the longterm application of skin-lightening creams containing hydroquinone. This irreversible disfiguring cosmetic problem assumes epidemic proportions in South African blacks. Mild ochronosis is characterized clinically
Mulligan R.P., Jordaan H.F.
core +1 more source