Results 41 to 50 of about 1,374 (165)

Expert Consensus on the Management of Hyperpigmentation Disorders in India: A Modified Delphi Study by the Pigmentary Disorders Society

open access: yesInternational Journal of Dermatology, EarlyView.
Delphi‐based expert consensus for diagnosis and management of common hyperpigmentation disorders in Indian dermatology practice, integrating evidence review, iterative voting, and consensus‐driven recommendations. ABSTRACT Hyperpigmentation disorders are prevalent in individuals with skin of color and are associated with considerable psychosocial ...
Rashmi Sarkar   +12 more
wiley   +1 more source

Alkaptonuria: A case report

open access: yesIndian Journal of Ophthalmology, 2017
Alkaptonuria is a rare inborn error of metabolism with autosomal recessive inheritance with a mutation in homogentisate 1,2-dioxygenase. It results in accumulation of homogentisic acid in connective tissues (ochronosis). Most common ocular manifestations
Nirupama Damarla   +5 more
doaj   +1 more source

Microcore Skin Biopsies: A Novel, Micro‐Invasive Skin Biopsy Technique Yielding Full‐Thickness Histology

open access: yesSkin Research and Technology, Volume 32, Issue 7, July 2026.
ABSTRACT Background Punch biopsies are considered the primary technique to obtain full‐thickness skin specimens for dermatologic diagnoses. However, limitations include scarring, sampling error, poor margin identification, and post‐sampling deformations.
Rebecca Lapides   +9 more
wiley   +1 more source

Treatment of Acne‐Induced Facial Post‐Inflammatory Hyperpigmentation With a New 2‐MNG‐Containing Routine Versus a Thiamidol‐Containing Routine—A Monocentric Prospective Double‐Blind Randomized Comparative Trial

open access: yesJournal of Cosmetic Dermatology, Volume 25, Issue 6, June 2026.
ABSTRACT Background Acne‐induced post‐inflammatory hyperpigmentation (PIHP) is a frequent condition. 2‐mercaptonicotinoyl glycine (2‐MNG) is an innovative anti‐pigmenting molecule. Aims The aim of this study is to compare the efficacy and tolerability of two routines in the treatment of PIHP: 2‐MNG‐containing serum + SPF50+/UVA sunscreen versus ...
Thierry Passeron   +7 more
wiley   +1 more source

Cucumber‐Derived Exosome‐Like Vesicles With Melanin‐Inhibitory Activity and an Acceptable in Vitro Safety Profile

open access: yesJournal of Cosmetic Dermatology, Volume 25, Issue 6, June 2026.
ABSTRACT Background Skin hyperpigmentation disorders affect millions worldwide, driving demand for depigmentation products. However, many conventional skin‐lightening products contain dangerous ingredients, including mercury and unregulated hydroquinone.
Che‐Yuan Hsu   +6 more
wiley   +1 more source

Lumbar disc herniation in ochronosis

open access: yesIndian Spine Journal, 2019
Alkaptonuria is a rare metabolic, autosomal recessive disorder caused by the deficiency of homogentisic acid oxidase and it is characterized by bluish-black discoloration of cartilages, skin (Ochronosis), degenerative changes in the articular, extra ...
Subbiah Jayakumar   +2 more
doaj   +1 more source

Comparison of the Efficacy of Kligman's Formula Combined With 30% Topical Metformin Versus Kligman's Formula Alone in the Treatment of Melasma

open access: yesJournal of Cosmetic Dermatology, Volume 25, Issue 6, June 2026.
ABSTRACT Background Melasma is a common hyperpigmentation disorder primarily affecting women, influenced by ultraviolet exposure, hormones, and genetics. Kligman's formula is a first‐line therapy, but emerging evidence suggests that topical metformin, an antidiabetic with antimelanogenic effects, may enhance treatment outcomes.
Fariba Iraji   +4 more
wiley   +1 more source

Hydroquinone‐Free, Tetrahexyldecyl Ascorbate Antioxidant Serum for Hyperpigmented and Photodamaged Skin to Achieve Skin Health

open access: yesJournal of Cosmetic Dermatology, Volume 25, Issue 4, April 2026.
ABSTRACT Background Ascorbic acid (AA) has protective and corrective functions critical for counteracting extrinsic and intrinsic skin aging and hyperpigmentation, but it is highly unstable, making it challenging to formulate into skincare products.
McKenzie E. Maloney   +4 more
wiley   +1 more source

Long‐Term Efficacy of Arthroscopic Microfracture Combined With Autologous Collagen‐Induced Chondrogenesis for Knee Cartilage Defects: A 5‐Year Prospective Pilot Randomized Controlled Trial

open access: yesOrthopaedic Surgery, Volume 18, Issue 4, Page 631-640, April 2026.
Arthroscopic microfracture combined with autologous collagen‐induced chondrogenesis provides superior long‐term cartilage regeneration and sustained clinical improvement in knee cartilage defects, as evidenced by 5‐year MRI and functional outcomes. ABSTRACT Objectives Cartilage defect of the knee joint is a common cause of knee pain and can result in ...
Shuofang Ren   +8 more
wiley   +1 more source

The Harmful Trifecta of Skincare in African and Asian Populations: Triple Action Creams, Skin‐Lightening Creams, and Antiseptic Soaps

open access: yes
JEADV Clinical Practice, EarlyView.
Olufolakemi Cole‐Adeife   +4 more
wiley   +1 more source

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