Results 21 to 30 of about 1,374 (165)
JIMD Reports, 2020 Background Increased homogentisic acid (HGA) causes ochronosis. Nitisinone decreases HGA. The aim was to study the effect of nitisinone on the ochronosis progression.
Lakshminarayan R. Ranganath +8 more
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European Journal of Cardio-Thoracic Surgery, 2003 A 63-year-old lady with alcaptonuria had aortic stenosis and was referred for aortic valve replacement. At operation the aorta appeared slate coloured. On aortotomy (Fig. 1) there was greyish black discoloration of the intimal surface of the aorta and left ventricular cavity. The aortic valve was also black in colour, stenotic and calcified.
S, Ghotkar, M, Kuduvalli, W, Dihmis
openaire +2 more sources
Ochronotic Arthropathy: A Report of Two Cases
Southern Clinics of Istanbul Eurasia, 2020 Ochronosis is an entity characterized by deposition of homogentisic acid and metabolites in connective tissues, such as joint cartilage, skin and sclera.
Selma Şengiz Erhan +3 more
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Bilateral Breast Ochronosis: a Case Report
JPRAS Open, 2021 : Ochronosis is a syndrome characterized by bluish black discoloration due to the deposition of polymerized products of homogentisic acid (HGA) in the connective tissues.
Fatema A.J. AbdulKarim +3 more
doaj +1 more source
Dermatology Online Journal, 2008 A 55-year-old woman with melasma develops biopsy-proved exogenous ochronosis in the setting of prolonged topical hydroquinone use. A limited number of similar reports exist in the US literature and are the basis for an FDA call to review hydroquinone-based products.
Merola, Joseph F +3 more
openaire +4 more sources
Ochronosis as an unusual cause of valvular defect: a case report
Journal of Medical Case Reports, 2009 Introduction Alkaptonuria (also known as ochronosis) is a genetic disorder characterised by the accumulation of homogentisic acid deposits in connective tissue. In rare cases, ochronosis can cause valvular heart disease.
Steverding Dietmar, Wilke Andreas
doaj +1 more source
Exogenous ochronosis superimposed on chronic kidney disease: A case report and review of literature
Sahel Medical Journal, 2018 Ochronosis is a rare disease characterized by speckled and diffuse pigmentation symmetrically over the face, neck, and photo-exposed areas. It can present in exogenous or endogenous form.
Ishrat Hussain Dar +4 more
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Endogenous ochronosis with keratoelastoidosis marginalis
Indian Journal of Dermatopathology and Diagnostic Dermatology, 2019 Endogenous ochronosis is a manifestation of alkaptonuria, a rare metabolic disease due to homogentisic acid oxidase deficiency. Darkened urine and arthropathy are the other two components that complete the triad of alkaptonuria. Pigmentation of skin, the
R Mythreyi +4 more
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КардиоСоматикаBACKGROUND: Ochronosis is a rare disorder caused by an inherited defect in tyrosine metabolism, in which the biochemical degradation pathway is interrupted at the stage of homogentisic acid formation.
Amina M. Alieva +6 more
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