Results 1 to 10 of about 2,076 (188)

Exogenous ochronosis [PDF]

Dermatologica Sinica, 2015
Exogenous ochronosis (EO) is a cutaneous disorder characterized by blue-black pigmentation resulting as a complication of long-term application of skin-lightening creams containing hydroquinone but may also occur due to topical contact with phenol or ...
Wei-Li Ko
doaj   +12 more sources

Total knee arthroplasty in ochronosis [PDF]

Arthroplasty Today, 2015
Alkaptonuria is disorder of tyrosine metabolism due to deficiency of homogentisic oxidase characterized by excretion of homogentisic acid in urine, deposition of oxidized homogensitate pigments in connective tissues and articular cartilages (ochronosis).
Vaibhav G. Patel, MBBS
exaly   +4 more sources

Blue man: Ochronosis in Otolaryngology

Clinical Case Reports (discontinued), 2022
Blue discoloration of the skin and cartilage, or ochronosis, is a rare physical examination finding. We present two cases of childhood onset ochronosis, one exogenous and one endogenous in etiology. The first was caused by minocycline use for severe acne,
Courtney Shires, Karuna Dewan
exaly   +2 more sources

Cardiac ochronosis with severe aortic and mitral valve stenosis: a challenge case [PDF]

Journal of Cardiothoracic Surgery
Ochronosis is a hereditary disorder characterized by black pigmentation in tissues. Cardiac ochronosis is most commonly associated with aortic stenosis, while mitral stenosis is a less frequently observed involvement.
Mukan Kağan Kuş, Burak Bozkurt, Talib Durak, İsmail Yücesin Arslan, Mehmet Kaplan   +4 more
doaj   +2 more sources

Non-Insulated Microneedle Radiofrequency for the Treatment of Hydroquinone-Induced Exogenous Ochronosis: A Case Report and Literature Review [PDF]

Clinical, Cosmetic and Investigational Dermatology
Namthong Wittayabusarakam, Suthinee Rutnin, Natthachat Jurairattanaporn Division of Dermatology, Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, ThailandCorrespondence: Natthachat Jurairattanaporn, Division ...
Wittayabusarakam N, Rutnin S, Jurairattanaporn N   +2 more
doaj   +2 more sources

Clinically probable alkaptonuria-associated ochronosis presenting as multilevel cervical disc herniation with myeloradiculopathy managed by three-level C4–7 anterior cervical discectomy and fusion: a case report [PDF]

Frontiers in Endocrinology
Background/introductionAlkaptonuria (AKU) is a rare disorder of tyrosine metabolism characterized by homogentisic acid accumulation and ochronotic pigment deposition in connective tissues.
Zichuan Wu, Zichuan Wu, Baifeng Sun, Junzhe Sheng, Yong Hu, Yong Hu, Yang Liu   +6 more
doaj   +2 more sources

A Dark Turn in the OR: Incidental Discovery of Ochronosis during Trauma Surgery: A Case Report [PDF]

Journal of Orthopaedic Case Reports
Introduction: Alkaptonuria is a rare autosomal recessive metabolic disorder caused by deficiency of homogentisic acid (HGA) oxidase, leading to the accumulation of HGA. The polymerized oxidation products of HGA in connective tissues, a condition known as
Kumar Parth, Maulik Kothari, Hunaid Haider, Maitreya Kedar, Chittaranjan Meshram, B S Shiyam   +5 more
doaj   +2 more sources

Cardiovascular involvement in Alcaptonuria: a case report on ochronotic aortic valve [PDF]

Journal of Cardiothoracic Surgery
Alcaptonuria is a rare autosomal recessive metabolic disorder. It is characterized by the accumulation of homogentisic acid–derived brown and bluish-black pigments in connective tissues, a condition known as ochronosis. This occurs due to a defect in the
Alizamin Yusifli, Ulusal Coskun, Yılmaz Deniz, Arzum Kale, Mehmet Fatih Ayık, Suat Buket   +5 more
doaj   +2 more sources

Ochronotic arthropathy: skeletal manifestations and orthopaedic treatment [PDF]

EFORT Open Reviews
Alkaptonuria is an extremely rare disorder of tyrosine metabolism caused by an autosomal recessive enzymatic deficiency of homogentisic acid (HGA) oxidase, causing its accumulation in collagenous structures, especially in hyaline cartilage.
Khaled Hamed Salem, Alyaa Diaa Elmoghazy
doaj   +2 more sources

Ochronotic arthropathy mimicking degenerative osteoarthritis in an older adult with alkaptonuria: diagnostic and perioperative lessons from a case report [PDF]

Frontiers in Medicine
BackgroundAlkaptonuria is a rare inherited metabolic disorder caused by impaired homogentisic acid metabolism. Ochronotic arthropathy is a late musculoskeletal manifestation and may mimic ordinary degenerative osteoarthritis in older adults.
Yong-Ming Zhang, Ji-Xin Chen, Lei Wan, Feng Ye   +3 more
doaj   +2 more sources