Dermatologica Sinica, 2015 Exogenous ochronosis (EO) is a cutaneous disorder characterized by blue-black pigmentation resulting as a complication of long-term application of skin-lightening creams containing hydroquinone but may also occur due to topical contact with phenol or ...
Wei-Li Ko
doaj +11 more sources
Total knee arthroplasty in ochronosis
Arthroplasty Today, 2015 Alkaptonuria is disorder of tyrosine metabolism due to deficiency of homogentisic oxidase characterized by excretion of homogentisic acid in urine, deposition of oxidized homogensitate pigments in connective tissues and articular cartilages (ochronosis).
Vaibhav G. Patel, MBBS
exaly +4 more sources
Indian Journal of Dermatology, 2000 Ochronosis is a rare disorder, which presents with distinct clinical and biochemical features. A fifty seven year old male presented with fracture femur, osteoarthritis, Oslerâ€s sign, alkaptonuria and cutaneous ochronosis.
Srikumar G +5 more
doaj +2 more sources
Blue man: Ochronosis in Otolaryngology
Clinical Case Reports (discontinued), 2022 Blue discoloration of the skin and cartilage, or ochronosis, is a rare physical examination finding. We present two cases of childhood onset ochronosis, one exogenous and one endogenous in etiology. The first was caused by minocycline use for severe acne,
Courtney Brooke Shires, Karuna Dewan
exaly +2 more sources
Cardiac ochronosis with severe aortic and mitral valve stenosis: a challenge case [PDF]
Journal of Cardiothoracic SurgeryOchronosis is a hereditary disorder characterized by black pigmentation in tissues. Cardiac ochronosis is most commonly associated with aortic stenosis, while mitral stenosis is a less frequently observed involvement.
Mukan Kağan Kuş +4 more
doaj +2 more sources
Ease of sutureless aortic valve replacement in a patient with unexpected ochronosis: a case report
Journal of Cardiothoracic SurgeryBackground Alkaptonuria is a rare congenital metabolic disorder characterized by homogentisic acid accumulation in body cartilage and connective tissues due to a deficient homogentisic acid dioxygenase enzyme.
Saeid Hosseini +5 more
doaj +2 more sources
Knee degenerative osteoarthritis secondary to ochronosis (case report) [PDF]
Travmatologiâ i Ortopediâ Rossii, 2013 Alkaptonuria is rare disease with deficiency of homogentisate-1,2-dioxygenase enzyme, resulting in excess deposition of homogentisic acid in connective tissue. This deposition leads to ochronosis - brownish-black pigmentation of connective tissue.
V. V. Bliznyukov +2 more
doaj +3 more sources
Non-Insulated Microneedle Radiofrequency for the Treatment of Hydroquinone-Induced Exogenous Ochronosis: A Case Report and Literature Review [PDF]
Clinical, Cosmetic and Investigational DermatologyNamthong Wittayabusarakam, Suthinee Rutnin, Natthachat Jurairattanaporn Division of Dermatology, Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, ThailandCorrespondence: Natthachat Jurairattanaporn, Division ...
Wittayabusarakam N +2 more
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Total Knee Arthroplasty in Alkaptonuric Ochronosis: the First Case Report in Thailand and Literature Review [PDF]
Siriraj Medical Journal, 2016 Ochronosis is a musculoskeletal manifestation found in alkaptonuria which is a rare autosomal recessive disorder caused by the deficiency of homogentistic acid oxidase enzyme. This leads to accumulation and deposition of homogentistic acid (HGA) pigments
Witchuree Wejjakul, Anuwat Pongkunakorn
doaj +4 more sources
Clinically probable alkaptonuria-associated ochronosis presenting as multilevel cervical disc herniation with myeloradiculopathy managed by three-level C4–7 anterior cervical discectomy and fusion: a case report [PDF]
Frontiers in EndocrinologyBackground/introductionAlkaptonuria (AKU) is a rare disorder of tyrosine metabolism characterized by homogentisic acid accumulation and ochronotic pigment deposition in connective tissues.
Zichuan Wu +6 more
doaj +2 more sources