Results 61 to 70 of about 1,374 (165)

Efficacy of Eflornithine Hydrochloride Cream in the Treatment of Melasma: A Randomized, Double‐Blinded, Split‐Face–Controlled Pilot Trial

Dermatologic Therapy, Volume 2026, Issue 1, 2026.
Background Melasma treatment remains challenging with variable response to conventional lightening agents. Polyamine inhibition via ornithine decarboxylase 1 (ODC1) may offer an alternative approach, with eflornithine hydrochloride being an established ODC1 inhibitor. Objectives To compare the efficacy and safety of eflornithine hydrochloride 13% cream
Jonathan Yongwei Boey, Xue Ting Ooi, Amanda Kuan, Sai Yee Chuah, Anjali Jhingan, Leah A. Vardy, Steven Thng, Yolanda Gilaberte   +7 more
wiley   +1 more source

A simplified staging system based on the radiological findings in different stages of ochronotic spondyloarthropathy

Indian Journal of Radiology and Imaging, 2013
This study describes a group of 26 patients with ochronotic spondyloarthropathy who were on regular treatment and follow-up at a tertiary level hospital and proposes a simplified staging system for ochronotic spondyloarthropathy based on radiographic ...
Isaac Jebaraj, Binita Riya Chacko, George Koshy Chiramel, Thomas Matthai, Apurve Parameswaran   +4 more
doaj   +1 more source

Clinically probable alkaptonuria-associated ochronosis presenting as multilevel cervical disc herniation with myeloradiculopathy managed by three-level C4–7 anterior cervical discectomy and fusion: a case report

Frontiers in Endocrinology
Background/introductionAlkaptonuria (AKU) is a rare disorder of tyrosine metabolism characterized by homogentisic acid accumulation and ochronotic pigment deposition in connective tissues.
Zichuan Wu, Zichuan Wu, Baifeng Sun, Junzhe Sheng, Yong Hu, Yong Hu, Yang Liu   +6 more
doaj   +1 more source

An unusual cause of chronic low back pain: ochronosis

The Pan African Medical Journal, 2017
A 45-year-old man presented with low back pain evolving since 8 years associated sometimes with a radicular radiation. The clinical examination found a patient in good general condition, a loss of the lumbar lordosis, an exaggeration of the dorsal ...
Zeineb Alaya, Anis Mzabi
doaj   +1 more source

Perioperative management of patient with alkaptonuria and associated multiple comorbidities

Journal of Anaesthesiology Clinical Pharmacology, 2011
Alkaptonuria is a rare inherited genetic disorder of tyrosine metabolism characterized by a triad of homogentisic aciduria, ochronosis, and arthritis. The most common clinical manifestations of ochronosis involve the musculoskeletal, respiratory, airway,
Ravindra Pandey, Anil Kumar, Rakesh Garg, Puneet Khanna, Vanlal Darlong   +4 more
doaj   +1 more source

Exogenous ochronosis in an elderly Indian male: A case report

Pigment International, 2019
Exogenous ochronosis (EO) is an infrequent cutaneous disorder characterized by blue-black hue in the skin due to the deposition of small ochre-colored pigment in the dermis secondary to prolonged skin lightening agents or unprotected sun exposure.
Chapalamadugu S Sindhu, Cordelia Babitha, Anuradha Priyadarshini, Mahalakshmi Veeraraghavan   +3 more
doaj   +1 more source

Expanding the Interface: Overlooked Dermatologic Disorders With Ocular Involvement

JEADV Clinical Practice, Volume 4, Issue 5, Page 1239-1243, December 2025.
A George
wiley   +1 more source

The Description of Dermoscopy and Wood’s Lamp on Melasma

Berkala Ilmu Kesehatan Kulit dan Kelamin (Periodical of Dermatology and Venerology), 2017
Background: Melasma is an acquired hypermelanosis disorder occurred symmetrically on the sun exposure area, predominantly on the face and neck. Melasma classification based on Wood’s light examination does not always have positive correlation with the ...
Ryski Meilia Novarina, Rahmadewi Rahmadewi, Hari Sukanto   +2 more
doaj   +1 more source

A CASE OF OCHRONOSIS [PDF]

BMJ, 1908
L C, Harston, A B, Soltau
openaire   +2 more sources

Ochronotic arthropathy mimicking degenerative osteoarthritis in an older adult with alkaptonuria: diagnostic and perioperative lessons from a case report

Frontiers in Medicine
BackgroundAlkaptonuria is a rare inherited metabolic disorder caused by impaired homogentisic acid metabolism. Ochronotic arthropathy is a late musculoskeletal manifestation and may mimic ordinary degenerative osteoarthritis in older adults.
Yong-Ming Zhang, Ji-Xin Chen, Lei Wan, Feng Ye   +3 more
doaj   +1 more source