Results 61 to 70 of about 2,140 (193)
Anais Brasileiros de Dermatologia, 2012 Exogenous ochronosis is a rare, cosmetically disfiguring condition, resulting from the longterm use of topical hydroquinone in treatment of melasma. It manifests as gray-brown or blue-black macules in hydroquinone-exposed regions.
Viviane Maria Rocha Martins +5 more
doaj +1 more source
Case Report: Ochronotic Arthropathy
Forbes Tıp Dergisi, 2021 Ochronosis is a rare metabolic disease caused by the deficiency of the homogentisic acid oxidase enzyme. It gives clinical findings related to the accumulation of homogentisic acid in soft tissues and excretion in urine. Patients with chronic arthropathy
Ülkü Dönmez +3 more
doaj +1 more source
Ochronosis Involvement and Extensity With 18F-FDG PET/CT
, 2019 Ochronosis (alkaptonuria) is an autosomal recessive inherited metabolic disease that causes pigmentation by accumulation of homogenous acid in the connective tissue.
Birlik, Merih +3 more
core +1 more source
Australasian Journal of Dermatology, Volume 67, Issue 5, Page e299-e306, August 2026.ABSTRACT Background/Objectives Post‐inflammatory hyperpigmentation (PIH) is a frequent sequela of acne in patients with skin of colour (SOC). While sunscreen is widely recommended for PIH prevention, little is known about real‐world sunscreen practices in this group. This study aimed to evaluate sunscreen use, barriers and factors influencing adherence
Xiaozhun Hang, Davin Sui Lim, Lisa Byrom
wiley +1 more source
Skin Research and Technology, Volume 32, Issue 7, July 2026.ABSTRACT Background Punch biopsies are considered the primary technique to obtain full‐thickness skin specimens for dermatologic diagnoses. However, limitations include scarring, sampling error, poor margin identification, and post‐sampling deformations.
Rebecca Lapides +9 more
wiley +1 more source
Spine fracture in ochronosis. Report of a case.
, 1992 Ochronosis, the musculoskeletal manifestation of alkaptonuria, primarily involves the larger joints of the body, including the spine. Ankylosis of the thoracolumbar spine leads to progressive loss of flexibility.
Millea, T P +3 more
core +1 more source
Journal of Cosmetic Dermatology, Volume 25, Issue 6, June 2026.ABSTRACT Background Acne‐induced post‐inflammatory hyperpigmentation (PIHP) is a frequent condition. 2‐mercaptonicotinoyl glycine (2‐MNG) is an innovative anti‐pigmenting molecule. Aims The aim of this study is to compare the efficacy and tolerability of two routines in the treatment of PIHP: 2‐MNG‐containing serum + SPF50+/UVA sunscreen versus ...
Thierry Passeron +7 more
wiley +1 more source
The effects of superoxide dismutase on osteoarticular cells and structural analysis of ochronosis, in a disease model of alkaptonuria [PDF]
, 2017 Introduction: Alkaptonuria (AKU) is a rare autosomal recessive condition resulting from deficiency of homogentisate 1,2 dioxygenase, causing inability to metabolise homogentisic acid (HGA).
Taylor, Adam +2 more
core +2 more sources
An elderly diabetic case of ochronosis with depression and chronic pain
, 2010 Alkaptonuria (ochronosis) is a rare autosomal recessive disorder featuring a genetic error in the amino acid metabolism. A defect in the tyrosine metabolism results in the accumulation and deposition of homogentisic acid in connective tissue, causing a ...
Bozoglu, Ergun +5 more
core +1 more source
Journal of Cosmetic Dermatology, Volume 25, Issue 6, June 2026.ABSTRACT Background Skin hyperpigmentation disorders affect millions worldwide, driving demand for depigmentation products. However, many conventional skin‐lightening products contain dangerous ingredients, including mercury and unregulated hydroquinone.
Che‐Yuan Hsu +6 more
wiley +1 more source