Results 51 to 60 of about 1,374 (165)

Exploring the Effectiveness, Tolerability, and Safety of the Adjunctive Use of Microneedling With Tranexamic Acid in the Treatment of Melasma

Journal of Cosmetic Dermatology, Volume 25, Issue 3, March 2026.
ABSTRACT Background Melasma is a chronic pigment disorder associated with significant psychosocial burden. The gold standard triple combination cream is effective but limited by relapse and adverse effects. Tranexamic acid (TXA) and microneedling have independently shown promise in the treatment of melasma, and their combined use may provide enhanced ...
Sharon Dhaliwal, Navneet Dhanoa, Zaina Rashid   +2 more
wiley   +1 more source

Tranexamic Acid for Hyperpigmentation Disorders: A Literature Review on Efficacy and Safety in Melasma and PIH

Journal of Cosmetic Dermatology, Volume 25, Issue 2, February 2026.
ABSTRACT Background Hyperpigmentation disorders, including melasma and post‐inflammatory hyperpigmentation (PIH), are common dermatologic conditions associated with significant cosmetic and psychological burden. Tranexamic acid (TXA), an antifibrinolytic agent, has gained increasing attention due to its anti‐inflammatory and antimelanogenic properties.
Ahmed AlJabr, Aseel Muhana I. AlAnazi, Rakan Abdulkarim A. AlEtebi   +2 more
wiley   +1 more source

Alkaptonuric patient presenting with “black” disc: a case report

Acta Orthopaedica et Traumatologica Turcica, 2020
Although intervertebral disc degeneration usually occurs in the natural course of alkaptonuria, detection of the disease by black disc material in a patient without any other sign of alkaptonuria is an extremely rare condition.
Ramazan Kahveci, Mehmet Fikret Ergungor, Ahmet Gunaydin, Atiye Temiz   +3 more
doaj   +1 more source

Sun Protection Advice for the South African Population for the Prevention and Management of Skin Diseases

International Journal of Dermatology, Volume 65, Issue 1, Page 57-68, January 2026.
ABSTRACT Sun protection is critical for the prevention and management of skin cancer and other photosensitive dermatoses in South Africa's diverse population. This review expands on previously published sun protection advice for skin cancer prevention by providing tailored advice for individuals with specific dermatological conditions.
Thuraya Isaacs, Tarryn Jacobs, Dagmar Whitaker, Willem Visser, Kim Wiid, Ncoza C. Dlova, Caradee Y. Wright, Bianca Tod   +7 more
wiley   +1 more source

Patellar ligament rupture during total knee arthroplasty in an ochronotic patient

Acta Orthopaedica et Traumatologica Turcica, 2020
Ochronotic arthropathy mainly involves the spine and large joints. Along with blackening of the joint, degeneration rapidly progresses mostly in the knee, resulting in symptoms by the 4th or 5th decade.
Madan Mohan Sahoo, Sudhir Kumar Mahapatra, Gopal Chandra Sethi, Sunil Kumar Dash   +3 more
doaj   +1 more source

International Expert Consensus on Knowledge Gaps in Care for Dermatologic Disorders in Skin of Color

International Journal of Dermatology, Volume 65, Issue 1, Page 41-56, January 2026.
State‐of‐the‐art knowledge gaps in dermatological disorders, photoprotection and procedural dermatology in individuals with skin of color (SOC). ABSTRACT Patients with skin of color (SOC) face unique dermatologic challenges that are often underrepresented in research and in dermatological education, creating critical gaps in care.
Henry W. Lim, Chengfeng Zhang, Marisa Taylor, Ncoza C. Dlova, Katleen Conceição, Nina Jablonski, Neha Gupta, Janet Wangari‐Olivero, Andrew Alexis   +8 more
wiley   +1 more source

Ochronotic Chronic Tendoachilles Rupture Management: A Case Series [PDF]

Journal of Foot and Ankle Surgery (Asia Pacific)
Background: Alkaptonuria is a rare inherited genetic disorder in which there is a deficiency of the enzyme homogentisate 1,2-dioxygenase. The three characteristics of alkaptonuria are homogentisic-aciduria, ochronosis, and ochronotic arthropathy ...
Jeremy B Dorai, Issac Jebaraj
doaj   +1 more source

Targeting Melasma: Innovations in Pigment Deposition and Photoaging in Cosmetic Dermatology

Journal of Cosmetic Dermatology, Volume 25, Issue 1, January 2026.
ABSTRACT Background Melasma is a chronic, relapsing hyperpigmentation disorder driven by complex interactions among genetic predisposition, hormonal fluctuations, UV exposure, oxidative stress, inflammation, and photoaging. Its psychosocial impact is substantial, especially among women with darker skin types, and treatment remains challenging due to ...
Ting Liao, Rui Luo, Ying Deng, Hongqiu Yang, Yu Du   +4 more
wiley   +1 more source

Overlapping Hyperpigmented and Poikilodermatous Mycosis Fungoides

Case Reports in Dermatological Medicine, Volume 2026, Issue 1, 2026.
Primary cutaneous T‐cell lymphomas (pCTCLs) are a heterogeneous group of rare clonal T‐cell disorders, among which mycosis fungoides (MF) is the most common subtype. Several clinicopathologic variants of MF have been described, including poikilodermatous and hyperpigmented forms, with occasional overlap between variants.
Joan Somja, Arjen F. Nikkels, Semonti Nandi   +2 more
wiley   +1 more source

The Use of Tranexamic Acid to Treat Melasma: A Systematic Review and Meta‐Analysis

Dermatologic Therapy, Volume 2026, Issue 1, 2026.
Introduction Tranexamic acid (TXA) is a synthetic derivative of the amino acid lysine that inhibits bleeding due to its effects on plasminogen conversion, approved by the FDA to treat menorrhagia and prevent bleeding in hemophilia patients undergoing dental extraction.
Nabila Scabine Pessotti, Vinicius Tassoni Civile, Talita Andrade Brandao, Felipe Ribeiro, Gisele Viana de Oliveira, Nathalia Sernizon Guimarães, Denise Steiner, Mahlatse Kgokolo   +7 more
wiley   +1 more source