Results 11 to 20 of about 2,646 (192)
Clinical Images: Stubborn low back pain under the eyes. [PDF]
ACR Open RheumatolACR Open Rheumatology, Volume 7, Issue 7, July 2025.
Gil W, Soubrier M.
europepmc +2 more sources
The not so familiar silent joint killer: Ochronosis – A case report with review of literature
Journal of Orthopaedic Diseases and Traumatology, 2022 Ochronosis is rarely considered a cause for knee synovitis due to its rare occurrence. It starts affecting the joint from the third decade onward causing premature joint damage.
Gowtham Bandi +4 more
doaj +1 more source
Ochronosis – a rare metabolic disease [PDF]
Romanian Journal of Rheumatology, 2021 Alkaptonuria is a rare disorder, an autosomal recessive condition with genetic determinism and hereditary transmission, having a prevalence of 1 per 1 million population in USA.
Patricia Richter +4 more
doaj +1 more source
Blue man: Ochronosis in Otolaryngology
Clinical Case Reports, 2022 Blue discoloration of the skin and cartilage, or ochronosis, is a rare physical examination finding. We present two cases of childhood onset ochronosis, one exogenous and one endogenous in etiology. The first was caused by minocycline use for severe acne,
Karuna Dewan +2 more
doaj +1 more source
An Unusual Presentation of Ochronosis with Palmar Pigmentation [PDF]
Journal of Clinical and Diagnostic Research, 2019 Ochronosis is the deposition of homogentisic acid in connective tissues resulting in bluish black discolouration. Hereby a case of ochronosis over the palmar surface of hand in 41-year-old male patient has been reported.
Mohan Rao Nandam +4 more
doaj +1 more source
Pigmented Rings With Central Clearing: A Dermoscopic Feature of Melasma. [PDF]
Australas J DermatolABSTRACT Melasma, a challenging pigmentary disorder affecting the face, often poses diagnostic difficulties due to its similarity to numerous other conditions. This study aimed to introduce and evaluate a novel dermoscopic feature, pigmented rings with central clearing (PRCC), in aiding the diagnosis of melasma and distinguishing it from similar ...
Punchihewa N +5 more
europepmc +2 more sources
Siriraj Medical Journal, 2016 Ochronosis is a musculoskeletal manifestation found in alkaptonuria which is a rare autosomal recessive disorder caused by the deficiency of homogentistic acid oxidase enzyme. This leads to accumulation and deposition of homogentistic acid (HGA) pigments
Witchuree Wejjakul, Anuwat Pongkunakorn
doaj +3 more sources
Targeting Melasma: Innovations in Pigment Deposition and Photoaging in Cosmetic Dermatology. [PDF]
J Cosmet DermatolABSTRACT Background Melasma is a chronic, relapsing hyperpigmentation disorder driven by complex interactions among genetic predisposition, hormonal fluctuations, UV exposure, oxidative stress, inflammation, and photoaging. Its psychosocial impact is substantial, especially among women with darker skin types, and treatment remains challenging due to ...
Liao T, Luo R, Deng Y, Yang H, Du Y.
europepmc +2 more sources
, 2013 Alkaptonuria (AKU) is a rare disorder of autosomal recessive inheritance. It is caused by a mutation in a gene that results in the accumulation of homogentisic acid (HGA).
Bukhari, Marwan +2 more
core +1 more source
A role for interleukins in ochronosis in a chondrocyte in vitro model of alkaptonuria [PDF]
, 2016 Objectives Alkaptonuria is a rare autosomal recessive condition resulting from inability to breakdown homogentisic acid (HGA); an intermediate in tyrosine degradation.
Bukhari, Marwan +3 more
core +1 more source