Results 51 to 60 of about 2,646 (192)
ABSTRACT Background Melasma is a chronic pigment disorder associated with significant psychosocial burden. The gold standard triple combination cream is effective but limited by relapse and adverse effects. Tranexamic acid (TXA) and microneedling have independently shown promise in the treatment of melasma, and their combined use may provide enhanced ...
Sharon Dhaliwal +2 more
wiley +1 more source
Lumbar disc herniation in ochronosis
Alkaptonuria is a rare metabolic, autosomal recessive disorder caused by the deficiency of homogentisic acid oxidase and it is characterized by bluish-black discoloration of cartilages, skin (Ochronosis), degenerative changes in the articular, extra ...
Subbiah Jayakumar +2 more
doaj +1 more source
ABSTRACT Background Hyperpigmentation disorders, including melasma and post‐inflammatory hyperpigmentation (PIH), are common dermatologic conditions associated with significant cosmetic and psychological burden. Tranexamic acid (TXA), an antifibrinolytic agent, has gained increasing attention due to its anti‐inflammatory and antimelanogenic properties.
Ahmed AlJabr +2 more
wiley +1 more source
Ochronosis is a cutaneous disorder caused by the accumulation of phenols, either endogenously as homogentisic acid in patients with alkaptonuria (autosomal recessive disorder with deficiency of the enzyme homogentisic acid oxidase), or exogenously in ...
Amir Qorbani +4 more
doaj
ABSTRACT Sun protection is critical for the prevention and management of skin cancer and other photosensitive dermatoses in South Africa's diverse population. This review expands on previously published sun protection advice for skin cancer prevention by providing tailored advice for individuals with specific dermatological conditions.
Thuraya Isaacs +7 more
wiley +1 more source
The pathogenesis of tendinopathy. A molecular perspective [PDF]
There are many publications that discuss the aetiology, diagnosis and treatment of the various forms of tendinopathy, but few are based on conclusive scientific evidence.
Riley, GP
core +1 more source
International Expert Consensus on Knowledge Gaps in Care for Dermatologic Disorders in Skin of Color
State‐of‐the‐art knowledge gaps in dermatological disorders, photoprotection and procedural dermatology in individuals with skin of color (SOC). ABSTRACT Patients with skin of color (SOC) face unique dermatologic challenges that are often underrepresented in research and in dermatological education, creating critical gaps in care.
Henry W. Lim +8 more
wiley +1 more source
Alkaptonuria is a rare inborn error of metabolism with autosomal recessive inheritance with a mutation in homogentisate 1,2-dioxygenase. It results in accumulation of homogentisic acid in connective tissues (ochronosis). Most common ocular manifestations
Nirupama Damarla +5 more
doaj +1 more source
The Use of Tranexamic Acid to Treat Melasma: A Systematic Review and Meta‐Analysis
Introduction Tranexamic acid (TXA) is a synthetic derivative of the amino acid lysine that inhibits bleeding due to its effects on plasminogen conversion, approved by the FDA to treat menorrhagia and prevent bleeding in hemophilia patients undergoing dental extraction.
Nabila Scabine Pessotti +7 more
wiley +1 more source
Total hip replacement in a black hip: a case report and review of literature [PDF]
Alkaptonuria is a rare metabolic disease leading to the accumulation of a blue-black pigment namely homogentisic acid in the cartilaginous tissue and body fluids giving them a black color. It is an autosomal recessive disease due to the deficiency of the
Gujjar, Pranay +4 more
core +2 more sources

