Results 41 to 50 of about 6,939 (158)

Ochronotic hip arthropathy – A case report

Journal of Orthopaedic Case Reports, 2022
Introduction: Ochronotic arthropathy is a rapidly progressive sequelae of alkaptonuria. This is a rare autosomal recessive condition caused by a mutation in the homogentisate 1,2 dioxygenase (HGD) gene leading to HGD enzyme deficiency. Here, we report a case of neck femur fracture in a patient with ochronotic arthropathy managed by primary hip ...
Jirel, Abhishek, Paul, Nirvin, Kaganur, Raghavendra, Gopurathingal, Anto, George, Joseph   +4 more
openaire   +2 more sources

Total Knee Arthroplasty in Ochronosis Arthropathy: A Case Report and Systematic Review

Case Reports in Orthopedics, Volume 2019, Issue 1, 2019., 2019
Introduction. Ochronosis arthropathy (OcA) is a rare condition which may be treated with total knee arthroplasty (TKA) at the end stage. The condition is often discovered only intraoperatively and the ideal choice of TKA is unknown. Case Presentation.
Wu Chean Lee, Tong Leng Tan, Ying Ho Chan, Werner Kolb   +3 more
wiley   +1 more source

Black hip: a rare case treated by total hip replacement

Annals of Saudi Medicine, 2013
BACKGROUND AND OBJECTIVE: Ochronic arthropathy of hip (Black Hip) is a rare clinical manifestation of congenital disorder of amino acid metabolism characterized by a classic triad: (1) degenerative arthritis, (2) ochronotic pigmentation, and (3) urine ...
Narayana Gowda, Mohan J. Kumar, Ajith K. Kumar   +2 more
doaj   +1 more source

Black Colouration of the Knee Articular Cartilage after Spontaneously Recurrent Haemarthrosis

Case Reports in Orthopedics, Volume 2016, Issue 1, 2016., 2016
Mild discolouration of the articular cartilage is known to gradually occur during aging. However, pathological tissue pigmentation is occasionally induced under several specific conditions. In the present case, we performed total knee replacement in a patient with recurrent haemarthrosis.
Kazu Matsumoto, Daichi Ishimaru, Hiroyasu Ogawa, Haruhiko Akiyama, Paul E. Di Cesare   +4 more
wiley   +1 more source

In Vivo Confocal Microscopy and Anterior Segment Optic Coherence Tomography Findings in Ocular Ochronosis

Case Reports in Ophthalmological Medicine, Volume 2015, Issue 1, 2015., 2015
Purpose. To report clinical and in vivo confocal microscopy (IVCM) findings of two patients with ocular ochronosis secondary due to alkaptonuria. Materials and Methods. Complete ophthalmologic examinations, including IVCM (HRT II/Rostock Cornea Module, Heidelberg, Germany), anterior segment optical coherence tomography (AS‐OCT) (Topcon 3D spectral ...
Elif Demirkilinc Biler, Suzan Guven Yilmaz, Melis Palamar, Pedram Hamrah, Afsun Sahin, Alexander A. Bialasiewicz   +5 more
wiley   +1 more source

Ochronotic arthropathy, an approach to osteoarthritis bone remodelling.

, 2006
The objective is to use hip ochronotic arthropathy for an indirect approach to osteoarthritis bone remodelling in a human joint via an identified causal chondropathy.
Lagier R
core   +1 more source

Amyloidosis, Inflammation, and Oxidative Stress in the Heart of an Alkaptonuric Patient

Mediators of Inflammation, Volume 2014, Issue 1, 2014., 2014
Background. Alkaptonuria, a rare autosomal recessive metabolic disorder caused by deficiency in homogentisate 1,2‐dioxygenase activity, leads to accumulation of oxidised homogentisic acid in cartilage and collagenous structures present in all organs and tissues, especially joints and heart, causing a pigmentation called ochronosis.
Lia Millucci, Lorenzo Ghezzi, Eugenio Paccagnini, Giovanna Giorgetti, Cecilia Viti, Daniela Braconi, Marcella Laschi, Michela Geminiani, Patrizia Soldani, Pietro Lupetti, Maurizio Orlandini, Chiara Benvenuti, Federico Perfetto, Adriano Spreafico, Giulia Bernardini, Annalisa Santucci, Giuseppe Valacchi   +16 more
wiley   +1 more source

Ochronotic arthropathy - Disappearance of alkaptonuria after liver transplantation for hepatitis B-related cirrhosis

, 2005
The deficiency of homogentisic acid oxidase, an enzyme that is mainly found in hepatocytes, is associated with alkaptonuria and ochronosis. We report a patient with clinical and radiologic findings of ochronotic arthropathy in whom alkaptonuria ...
Oder, G, Inal, V, Kobak, N, Kobak, AC, Argin, M   +4 more
core   +2 more sources

Patellar ligament rupture during total knee arthroplasty in an ochronotic patient

Acta Orthopaedica et Traumatologica Turcica, 2020
Ochronotic arthropathy mainly involves the spine and large joints. Along with blackening of the joint, degeneration rapidly progresses mostly in the knee, resulting in symptoms by the 4th or 5th decade.
Madan Mohan Sahoo, Sudhir Kumar Mahapatra, Gopal Chandra Sethi, Sunil Kumar Dash   +3 more
doaj   +1 more source

Analysis of the Phenotype Differences in Siblings with Alkaptonuria

Metabolites, 2022
Alkaptonuria (AKU) is a rare autosomal recessive disorder caused by mutations within a gene coding for homogentisate 1,2-dioxygenase (HGD). To date, 251 different variants of this gene have been reported.
Andrea Zatkova, Birgitta Olsson, Lakshminarayan R. Ranganath, Richard Imrich   +3 more
doaj   +1 more source