Results 51 to 60 of about 919 (164)
Exploring Matrix Stiffness‐Related Gene in Periodontitis: A Comprehensive Multidataset Analysis
Mediators of Inflammation, Volume 2026, Issue 1, 2026.Background
Characterized by the progressive deterioration of periodontal supporting tissues, periodontitis (PD) is a prevalent oral disorder primarily instigated by dental plaque biofilms. Matrix stiffness (MS), a key extracellular matrix (ECM) property, regulates inflammatory cell function and tissue repair balance.Yanhui Peng, Xiaoqin Yang, Wei Fang, Lifang Zhang, Ting Guo, Hongyu Zheng, Cristin Coman +6 morewiley +1 more sourceA gene panel to predict response to adjuvant chemotherapy and risk of recurrence in colorectal cancer
Malignancy Spectrum, Volume 2, Issue 2, Page 84-94, June 2025.This study compared microarray and transcriptome sequencing data generated in colorectal tumors with good response and no response to adjuvant chemotherapy. The study identified the upregulation in two genes (PTGIS/LYVE1) to be associated with no response and risk of recurrence. The addition of drugs targeting these genes may improve response. Abstract Steffie Urmila Avanthi, Ravikanth Vishnubhotla, Mitnala Sasikala, Guduru Venkat Rao, Rebala Pradeep, Sanjeev Marigowda Patil, Anuradha Sekaran, Jain Aviral, Sonali Mondkar, Nageshwar Reddy Duvvur +9 morewiley +1 more sourceTraumatic Macular Hole: Diagnosis, Natural History, and Management
Journal of Ophthalmology, Volume 2019, Issue 1, 2019., 2019 Traumatic macular hole occurs most often in young men and can present after various types of injuries. Traumatic macular holes result from anteroposterior and tangential vitreoretinal traction and may exhibit concurrent additional pathologies such as Berlin’s edema and subretinal fluid. Optical coherence tomography can play an essential role in patient Greg Budoff, Neelakshi Bhagat, Marco A. Zarbin, Claudio Azzolini +3 morewiley +1 more sourceINTRAVITREAL OCRIPLASMIN IN CLINICAL PRACTICE
, 2018 To investigate predictors of success, visual outcomes, and complications of intravitreal ocriplasmin for the treatment of symptomatic vitreomacular adhesion in a clinical care setting.Kunjal K. Modi, Feng, Henry L, Hasan, Aisha, Feuer, William J, H. Matthew Wheatley, Henry L. Feng, Fine, Howard F, Howard F. Fine, Jonathan L. Prenner, Aisha Hasan, Wheatley, H Matthew, Modi, Kunjal K, Shah, Sumit P, Daniel B. Roth, Prenner, Jonathan L, Roth, Daniel B, Sumit P. Shah, William J. Feuer +17 morecore +1 more sourceBioinformatics analysis of candidate genes and potential therapeutic drugs targeting adipose tissue in obesity
Adipocyte, 2022 Obesity is a complex medical condition that affects multiple organs in the body. However, the underlying mechanisms of obesity, as well as its treatment, are largely unexplored.Yun Yu, Yu-Han Zhang, Liang Liu, Ling-Ling Yu, Jun-Pei Li, Jing-an Rao, Feng Hu, Ling-Juan Zhu, Hui-Hui Bao, Xiao-Shu Cheng +9 moredoaj +1 more sourceVitrectomy in Small idiopathic MAcuLar hoLe (SMALL) study: Internal limiting membrane peeling versus no peeling
Acta Ophthalmologica, Volume 103, Issue 3, Page e156-e164, May 2025.Abstract Purpose
To compare vitrectomy with and without internal limiting membrane (ILM) peeling in small idiopathic macular holes. Methods
Retrospective multicentre study including consecutive eyes with ≤250 μm idiopathic macular hole treated with vitrectomy. The primary outcome was hole closure rate.Paola Marolo, Paolo Caselgrandi, Matteo Fallico, Guglielmo Parisi, Enrico Borrelli, Federico Ricardi, Francesco Gelormini, Luca Ceroni, Michele Reibaldi, SMALL Study Group, Tommaso Micelli Ferrari, Massimo Lorusso, Vito Primavera, Gianluigi Giuliani, Cesare Mariotti, Marco Lupidi, Luca Ventre, Giulia Pintore, Lorenzo Motta, Matteo Ripa, Francesco Boscia, Giacomo Boscia, Mario R Romano, Mariantonia Ferrara, Kacerik Miroslav, Daniele Marchina, Barbara Parolini, Enrico Peiretti, Viola Marchiori, Roberto Dell’Omo, Marzia Affatato, Teresio Avitabile, Andrea Russo, Antonio Longo, Vincenzo Scorcia, Adriano Carnevali, Rodolfo Mastropasqua, Lisa Toto, Agostino Salvatore Vaiano, Riccardo Merli, Marco Mura, Marco Pellegrini, Fabrizio Giansanti, Cristina Nicolosi, Matteo Badino, Nicola Pallozzi Lavorante, Maria T. Sandinha, Francesco Maria D’Alterio, Mario Damiano Toro, Robert Rejdak, Paolo Chelazzi, Claudia Azzolini, Francesco Viola, Caterina Donà, Matteo Giuseppe Cereda, Marco Casaluci, Marco Codenotti, Lorenzo Iuliano, Grazia Pertile, Daniele Sindaco, Stefano De Cillà, Andrea Muraca, Vincenza M.E. Bonfiglio, Maria Vadalà, Alberto La Mantia, Viviana Randazzo, Tito Fiore, Gianluigi Tosi, Rino Frisina, Chiara Angeli, Marco Coassin, Mariateresa Laborante, Tommaso Rossi, Pamela Cosimi, Stanislao Rizzo, Matteo Mario Carlà, Magda Gharbiya, Giuseppe Maria Albanese, Luigi Caretti, Edoardo Angelini, Gian Marco Tosi, Tommaso Bacci, David H Steel, Nikolaos Dervenis, Iordanis Vagiakis, Daniele Tognetto, Marco Rocco Pastore, Francesco Faraldi, Carlo Alessandro Lavia, Paolo Lanzetta, Daniele Veritti, Leopoldo Rubinato, Paolo Radice, Andrea Govetto +93 morewiley +1 more sourceA Comparative Study of Vitrectomy Combined with Internal Limiting Membrane Peeling for the Treatment of Idiopathic Macular Hole with Air or C3F8 Intraocular Tamponade
Journal of Ophthalmology, Volume 2018, Issue 1, 2018., 2018 Purpose. The treatment of idiopathic macular holes has been basically modeled, and vitreoretinal surgery is recognized as an effective treatment. However, the postoperative tamponade of gas will still make the patient uncomfortable and may have related complications. The purpose of this study is to investigate whether air as an intraocular tamponade is Xiang Chen, Yi Yao, Xiaolu Hao, Xiaocui Liu, Tiecheng Liu, Dirk Sandner +5 morewiley +1 more sourceVitreoschisis‐induced vitreous cortex remnants in proliferative vitreoretinopathy: A comprehensive review from basic research to clinical practice
Acta Ophthalmologica, Volume 102, Issue 8, Page 859-880, December 2024.Abstract
Proliferative vitreoretinopathy (PVR) significantly impacts the prognosis of rhegmatogenous retinal detachment (RRD), one of the most critical and increasing causes of vision loss in the Western world. Despite advancements in surgical instruments and techniques, the failure rate due to PVR remains substantial, necessitating additional ...Koen A. van Overdam, Marc Veckeneer, Emine Kiliç, Peter G. van Etten, Jerry Sebag, Jan C. van Meurs +5 morewiley +1 more sourceRelease of experimental retinal vein occlusions by direct intraluminal injection of ocriplasmin [PDF]
, 2016 Purpose Retinal vein occlusions (RVO) are a major cause of vision loss in people aged 50years and older. Current therapeutic options limit the consequences of RVO but do not eliminate the cause.Meenink, Thijs C.M., Janssens, Tom, Jonckx, Bart, Stassen, Jean Marie, Beelen, Maarten J., Vanheukelom, Valérie, Naus, Gerrit J.L., de Smet, Marc D. +7 morecore +1 more source