The effects of systemic diseases, genetic disorders and lifestyle on keloids
Abstract Keloid are a fibroproliferative disorder caused by abnormal healing of skin, specifically reticular dermis, when subjected to pathological or inflammatory scars demonstrating redness, elevation above the skin surface, extension beyond the original wound margins and resulting in an unappealing cosmetic appearance.
Guangpeng Xia +4 more
wiley +1 more source
Parity-Progression Fertility Tables for the Nationalities of the USSR [PDF]
Using data from a socio-demographic survey conducted in 1985 in the USSR, fertility parity-progression tables were constructed for the 17 most populated Soviet nationalities.
Darsky, L., Scherbov, S.
core
Structural insights into Legionella RidL-Vps29 retromer subunit interaction reveal displacement of the regulator TBC1D5 [PDF]
Legionella pneumophila can cause Legionnaires’ disease and replicates intracellularly in a distinct Legionella-containing vacuole (LCV). LCV formation is a complex process that involves a plethora of type IV-secreted effector proteins.
Bärlocher, K +8 more
core +4 more sources
Structural characterization of the Sel1‐like repeat protein LceB from Legionella pneumophila
Abstract Legionella are freshwater Gram‐negative bacteria that in their normal environment infect protozoa. However, this adaptation also allows Legionella to infect human alveolar macrophages and cause pneumonia. Central to Legionella pathogenesis are more than 330 secreted effectors, of which there are nine core effectors that are conserved in all ...
Tiffany V. Penner +6 more
wiley +1 more source
Modeling of chemical wear in ferrous alloys/silicon nitride contacts during high speed cutting [PDF]
The wear resistance of SisN4 in machining of iron alloys can be surprisingly low due to chemical affinity for dissolution in the metal. This limits the use of SisN4 inserts in high speed machining of steels, while Si3N4 retains the best performance of ...
Castro, F. +3 more
core +1 more source
Legionella pneumophila is a freshwater bacterium that replicates in predatory amoeba and alveolar macrophage. The ability of L. pneumophila to thrive in eukaryotic host cells is conferred by the Legionella containing vacuole (LCV).
K. Voth +5 more
semanticscholar +1 more source
Systematic proteomic analysis of LRRK2-mediated Rab GTPase phosphorylation establishes a connection to ciliogenesis [PDF]
We previously reported that Parkinson's disease (PD) kinase LRRK2 phosphorylates a subset of Rab GTPases on a conserved residue in their switch-II domains (Steger et al., 2016) (PMID: 26824392). Here, we systematically analyzed the Rab protein family and
Alessi, Dario R. +11 more
core +3 more sources
Background Oculocerebrorenal syndrome of Lowe is an X-linked disorder with very low prevalence in the general population. The OCRL gene encodes the protein phosphatidylinositol 4,5-bisphosphate-5-phosphatase, a lipid phosphatase, located in the trans ...
P. Tatsi +6 more
doaj +1 more source
Pump-to-signal transfer of low-frequency intensity modulation in fiber optical parametric amplifiers [PDF]
This paper describes the theoretical and experimental investigation of the transfer of low-frequency intensity modulation (IM) from pump to signal in fiber optical parametric amplifiers (OPAs).
Kalogerakis, G +3 more
core +1 more source
Lowe Syndrome (Oculo-cerebro-renal Syndrome of Lowe): A Case Report from Eastern India [PDF]
Lowe syndrome (the oculocerebrorenal syndrome of Lowe, OCRL) is a rare X-linked recessive metabolic disorder that primarily affects eyes, kidneys and brain. It is caused by the deficiency of enzyme phosphatidylinositol 4, 5-bisphosphate 5-phosphatase.
Dipankar Das +2 more
doaj

