Results 201 to 210 of about 54,485 (283)
Cancer Reports, Volume 9, Issue 10, October 2026.ABSTRACT Background Prostate cancer (PCa) is the most common solid tumor in American men, with persistent ethnic disparities, particularly among Hispanic American (HA) men. The tumor microenvironment (TME) and tumor genomics may contribute to disease progression but remain undercharacterized in HA populations.
Alejandro Recio‐Boiles +10 more
wiley +1 more source
miR-424-5p Regulates Stem-like and Malignant Phenotypes in Osteosarcoma by Targeting FZD4. [PDF]
Cancers (Basel)Ma J +10 more
europepmc +1 more source
Journal of Extracellular Vesicles, Volume 15, Issue 10, October 2026.Heparin augments EV yield in culture by inhibiting EV binding to cell‐surface HSPG and masking EV surface. Preventing autocrine and homotypic paracrine EV uptake during cell culture results in EV accumulation and higher yield. Heparin improved EV recovery after storage in NaCl but not in complex media or protein‐rich buffer(Please see Figure 9 for ...
André Cronemberger Andrade +13 more
wiley +1 more source
RHEBL1 expression is activated by the Oct4-Sox2 complex in oral squamous cell carcinoma. [PDF]
Funct Integr GenomicsQiu F +8 more
europepmc +1 more source
MedComm, Volume 7, Issue 10, October 2026.Polyploid giant cancer cells (PGCCs) arise in response to stress and play a critical role in therapy resistance and tumor dormancy. These cells can evade conventional treatments and later contribute to cancer relapse by generating progeny through nonmitotic, amitotic mechanisms.
Silvia Guil‐Luna +3 more
wiley +1 more source
Validation of Optimal Reference Genes for qRT-PCR in Adipose- and Uterine-Derived Feline Mesenchymal Stem Cells. [PDF]
Vet SciMiah R +12 more
europepmc +1 more source
Cancer Cell Metastasis: From Molecular Mechanisms to Therapeutic Strategies
MedComm, Volume 7, Issue 10, October 2026.The schematic representation of intrinsic and extrinsic influences of cancer cell metastasis. Genomic evolution of metastatic tumor cells (MTCs) promotes their metastatic phenotypes and reconstruct the primary tumor microenvironment. During MTCs migration along different routes (blood circulation, lymphatic vessels, and perineuronal spaces), the ...
Yupeng Zhao +7 more
wiley +1 more source
MedComm, Volume 7, Issue 10, October 2026.The Hippo–YAP/TAZ–TEAD pathway integrates mechanical and biochemical cues to govern organ growth, regeneration, cancer, and fibrosis. This review dissects pathway physiology, TEAD structural pharmacology and ligandable pockets, and therapeutic strategies spanning palmitoylation‐pocket inhibitors, PROTAC degraders, and gene/RNA therapies, highlighting ...
Xiaodan Qu, Zhan‐you Wang
wiley +1 more source
Human β‐Cell Dedifferentiation and Diabetes
Journal of Diabetes, Volume 18, Issue 10, October 2026.Human β‐cell dedifferentiation is inversely associated with HOMA‐β and occurs in Type 2 diabetes, Type 3c diabetes, and age‐related diabetes, potentially before hyperglycemia develops. Progressive loss of β‐cell identity is accompanied by dedifferentiation and transdifferentiation, suggesting that reversing these cell‐state changes may help restore ...
Jiajun Sun, Jinsook Son, Qidi Wang
wiley +1 more source
Aging Cell, Volume 25, Issue 10, October 2026.In contrast to rapid epigenetic de‐aging during induced pluripotent stem cell generation, direct conversion of blood cells into neural stem cells is associated with largely protracted epigenetic de‐aging. The process coincides with prolonged cell fate consolidation, does not require sustained proliferation, and might provide experimental access to ...
Lea Jessica Berg +8 more
wiley +1 more source