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The role of octacalcium phosphate in subcutaneous heterotopic calcification

Calcified Tissue International, 1985
Comparison of lattice parameters and morphology of some of the microcrystallites in a subcutaneous heterotopic calcification reported by Daculsi et al. [1] with those of heat-treated octacalcium phosphate (OCP) suggests that OCP is one of the mineral phases in dense globules and one of the precursors for the apatite.
M S, Tung, W E, Brown
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Importance of nucleation in transformation of octacalcium phosphate to hydroxyapatite

Materials Science and Engineering: C, 2014
Octacalcium phosphate (OCP) is regarded as an in vivo precursor of hydroxyapatite (HA). It is important to understand the mechanism of transformation of OCP to HA in order to reveal the mechanism of mineralization and help in the development of artificial bone-repairing materials.
Natsuko, Ito   +3 more
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Effect of sodium polyacrylate on the hydrolysis of octacalcium phosphate

Journal of Inorganic Biochemistry, 2000
Octacalcium phosphate (OCP) hydrolysis into hydroxyapatite (HA) has been investigated in aqueous solutions at different concentrations of sodium polyacrylate (NaPA). In the absence of the polyelectrolyte, OCP undergoes a complete transformation into HA in 48 h. The hydrolysis is inhibited by the polymer, which is significantly adsorbed on the crystals,
A, Bigi   +4 more
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Reversible Structural Changes of Octacalcium Phosphate and Labile Acid Phosphate

Journal of Dental Research, 1995
Acid phosphate is one of the major impurities incorporated into bioapatites, and its quantity and environment in forming mineral have been used as diagnostic probes to pursue acidic precursor(s). Currently, little is known about the structural feature of non-stoichiometric octacalcium phosphate (OCP), which has been advocated to be, most plausibly ...
O, Suzuki   +3 more
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Preparation of octacalcium phosphate by the hydrolysis of ?-tricalcium phosphate

Journal of Materials Science, 1980
A new simple method of preparation for the thermodynamically unstable octacalcium phosphate [Ca8H2(PO4)6·5H2O; OCP] has been developed using the hydrolysis of α-Ca3(PO4)2 instead of the conventional hydrolysis of CaHPO4·2H2O. The hydrolysis experiments were carried out by treating an α-Ca3(PO4)2(1 g)-H2O(50 m) suspension for 3 h at temperatures in the ...
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Functionalization of octacalcium phosphate for bone replacement

2020
The role of foreign ions on the properties of octacalium phosphate, although investigated by a limited number of studies, has been addressed for some time now and has provided useful information to clarify the biomineralization processes of the hard tissues of vertebrates.
Bigi A., Boanini E.
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An octacalcium phosphate intermediate in the synthesis of chromatographic hydroxyapatite

Biochimica et Biophysica Acta (BBA) - General Subjects, 1980
In the laboratory synthesis of hydroxyapatite for liquid column chromatography different procedures give varying amounts of a transient intermediate, identified by X-ray diffraction as octacalcium phosphate. The intermediate is most abundant in a recently-developed method involving conversion from brushite at neutral pH; well-crystallized ...
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Octacalcium phosphate carboxylates

Journal of Crystal Growth, 1994
Milenko Marković   +2 more
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Similarity of Octacalcium Phosphate and Hydroxyapatite Structures

Nature, 1963
THE formation of lamellar mixed crystals of hydroxy-apatite and Octacalcium phosphate have been postulated by Brown et al.1 to account for ‘defect apatites’ and other properties of precipitated calcium phosphate salts. One of the mechanisms they suggested for the layering is that of epitaxial overgrowths, since some similarity of structure was ...
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