Background: Lymphorrhea is a minor complication after kidney transplantation but may develop into a lymphocele and prolong hospital stay. Treatment is conservative based on percutaneous drainage until lymphatic leakage cessation.
Vaibhav Kant Baderiya +2 more
doaj +1 more source
Systemic Bevacizumab for Severe Bleeding From Acquired Gastrointestinal Vascular Malformations
Targeted antiangiogenic therapy with systemic bevacizumab for bleeding from acquired GI VMs was found to be safe and effective for chronic and severe bleeding from acquired vascular malformations due to idiopathic angiodysplasia, chronic liver disease, and deficiencies of von Willebrand factor, in a patient population comprised mostly of heavily ...
Nardeen E. Ayad +5 more
wiley +1 more source
Octreotide long-acting repeatable in the treatment of neuroendocrine tumors: patient selection and perspectives [PDF]
Hanford Yau,1 Mustafa Kinaan,2 Suzanne L Quinn,3 Andreas G Moraitis3 1Division of Endocrinology, Diabetes, and Metabolism, University of California, San Francisco (Fresno Division), Fresno, CA, USA; 2Division of Internal Medicine, University of Central ...
Quinn SL, Yau H, Moraitis AG, Kinaan M
core
Subcutaneously Administered Self-Cleaving Hydrogel–Octreotide Conjugates Provide Very Long-Acting Octreotide [PDF]
We developed a long-acting drug-delivery system that supports subcutaneous administration of the peptidic somatostatin agonist octreotidea blockbuster drug used to treat acromegaly and neuroendocrine tumors. The current once-a-month polymer-encapsulated
Gary W. Ashley (1653217) +4 more
core +1 more source
Automated GMP compliant production of [18F]AlF-NOTA-octreotide
Background Gallium-68 labeled synthetic somatostatin analogs for PET/CT imaging are the current gold standard for somatostatin receptor imaging in neuroendocrine tumor patients.
Térence Tshibangu +7 more
doaj +1 more source
The impact of medication shortages on paediatric care: A retrospective impact analysis
Aims Medication shortages are a growing global concern, with potentially greater consequences in paediatric patients because of the limited availability of safe, evidence‐based and appropriately formulated medication. This study aimed to evaluate the impact of medication shortages on paediatric patients by assessing the suitability and safety of ...
Maaike Johanna Rutten ‐ van Kranenburg +6 more
wiley +1 more source
Congenital Chylothorax: controversies [PDF]
RESUMO O quilotórax é o derrame pleural neonatal mais frequente, apesar de representar um diagnóstico raro. A sua etiologia é na maioria dos casos traumática pós-cirúrgica, estando também descrita a associação a cromossomopatias, situações que ...
Lira, S. +5 more
core
Pre-clinical comparison of [DTPA0] octreotide, [DTPA0,Tyr3] octreotide and [DOTA0,Tyr3] octreotide as carriers for somatostatin receptor-targeted scintigraphy and radionuclide therapy [PDF]
We have evaluated the potential usefulness of radiolabelled [DTPA0,Tyr3]octreotide and [DOTA0,Tyr3]octreotide as radiopharmaceuticals for somatostatin receptor-targeted scintigraphy and radiotherapy.
Bakker, Willem H. +10 more
core +1 more source
Diagnostic efficiency of 68Ga-DOTATATE PET/CT as compared to 99mTc-Octreotide SPECT/CT and conventional morphologic modalities in neuroendocrine tumors [PDF]
Objective(s): In view of somatostatin receptor (SSR) expression on cell membranes of the majority of neuroendocrine tumors (NETs), functional imaging exploiting analogs of SSR alongside the anatomical imaging is the mainstay of this diagnostic modality ...
Babak Fallahi +8 more
doaj +1 more source
ABSTRACT Somatostatin receptors (SSTR) mediate the antiproliferative, antisecretory, and proapoptotic effects of somatostatin and its synthetic analogs. Their surface expression on neuroendocrine tumor (NET) cells is required for somatostatin analog therapy and radiopharmaceutical therapy (RPT).
Neeraj Kumari +10 more
wiley +1 more source

