Results 61 to 70 of about 27,411 (201)

Beneficial effects of octreotide in alcohol-induced neuropathic pain. Role of H 2S, BDNF, TNF-α and Nrf2

Acta Cirúrgica Brasileira, 2021
Purpose To explore the role and molecular mechanisms of neuroprotective effects of octreotide in alcohol-induced neuropathic pain. Methods Male Wistar rats were employed and were administered a chronic ethanol diet containing 5% v/v alcohol for 28 days.
Rongqiang Jiang, Hongxia Wei
doaj   +1 more source

Semaglutide for Treating Paediatric Craniopharyngioma‐Related Obesity: A Multicentre Case Series

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Obesity is a complication of childhood craniopharyngioma that remains difficult to treat. We investigated whether semaglutide was associated with a decrease in BMI among adolescents with craniopharyngioma‐related obesity. Material and Methods This multicentre retrospective study included 20 patients < 18 years old with craniopharyngioma ...
Joanne Dornberger, Pascal Barat, Karine Aouchiche, Kevin Perge, Carine Villanueva, Sarah Castets, Natacha Bouhours‐Nouet, Aurelie Donzeau, Lucie Levaillant, Cecile Teinturier, Rachel Reynaud, Ahlam Azar‐Kolakez, Laetitia Martinerie, Dulanjalee Kariyawasam, Regis Coutant   +14 more
wiley   +1 more source

Internalization of radiolabelled [DTPA0]octreotide and [DOTA0,Tyr3]octreotide: Peptides for somatostatin receptor-targeted scintigraphy and radionuclide therapy

, 1998
We compared the internalization of [90Y-DOTA0,Tyr3]octreotide and [111In-DOTA0,Tyr3]octreotide with that of [125I-Tyr3]octreotide and [111In-DTPA0]octreotide in the subtype 2 somatostatin receptor (sst2)- positive rat pancreatic tumour cell lines CA20948
Mäcke, H.R. (Helmut), Bruin, E. (Erwin), Bakker, W.H. (Willem), Gameren, A. van, Krenning, E.P. (Eric), Visser, T.J. (Theo), Jong, M. (Marcel) de, Bernard, B.F. (Bert)   +7 more
core   +1 more source

Clinical Outcomes of Antrectomy for Patients With Multiple Type I Gastric Neuroendocrine Tumors: A Case Series

DEN Open, Volume 7, Issue 1, April 2027.
Type I gastric neuroendocrine tumors (T1‑GNETs) often present as multiple lesions, complicating treatment. This retrospective case series study evaluates antrectomy outcomes in eight patients with persistent multiple T1‑GNETs during 2005–2023. Following antrectomy, tumor regression was observed in two patients and complete disappearance in six, with ...
Yuki Morita, Ken Namikawa, Kaoru Nakano, Wataru Kurihara, Hiroyuki Yamamoto, Yusuke Horiuchi, Akiyoshi Ishiyama, Toshiyuki Yoshio, Souya Nunobe, Toshiaki Hirasawa   +9 more
wiley   +1 more source

Successful treatment of enterocutaneous fistula in a premature newborn by using octreotide

The Turkish Journal of Pediatrics, 2004
A premature newborn with an enterocutaneous fistula after repair of duodenal perforation is reported to emphasize the therapeutic effect of octreotide in persistent fistula even in a very small infant.
Ilker Büyükyavuz, Ibrahim Karnak, Sule Yiğit, F Cahit Tanyel   +3 more
doaj   +1 more source

Epigenetic Dysregulation of Somatostatin Receptors (SSTR) 1–5 and Therapeutic Implications in Neuroendocrine and Non‐Neuroendocrine Malignancies

International Journal of Cancer, Volume 159, Issue 11, Page 2633-2652, 1 December 2026.
ABSTRACT Somatostatin receptors (SSTR) mediate the antiproliferative, antisecretory, and proapoptotic effects of somatostatin and its synthetic analogs. Their surface expression on neuroendocrine tumor (NET) cells is required for somatostatin analog therapy and radiopharmaceutical therapy (RPT).
Neeraj Kumari, Pablo Hoffmann, Laura Reichl, Maximilian Schmutz, Nina Fischer, Thi Tuong Vi Dang, Fulvia Ferrazzi, Pascal Johann, Michaela Kuhlen, Constantin Lapa, Rainer Claus   +10 more
wiley   +1 more source

Octreotide-LAR in later-stage autosomal dominant polycystic kidney disease (ALADIN 2): A randomized, double-blind, placebo-controlled, multicenter trial

, 2019
BackgroundAutosomal dominant polycystic kidney disease (ADPKD) is the most frequent genetically determined renal disease. In affected patients, renal function may progressively decline up to end-stage renal disease (ESRD), and approximately 10% of those ...
Flavio Gaspari, Dugo M., Imbriaco M., Piero Ruggenenti, Andrea Remuzzi (506907), Antonio Granata, Giuseppe Remuzzi, Sandro Sironi, ALADIN 2 Study Group, Trillini M., Nadia Rubis (6560240), Riccio E., Mauro Dugo (180745), Nadia Rubis, Prandini S., Matias Trillini (6560225), Sara Gamba, Alessandro Villa, Piero Ruggenenti (180711), Pisani A., Giovanni Morana (6560231), Alessandro Villa (2455165), Silvia Prandini (180731), Giovanni Morana, Gamba S., Matias Trillini, Remuzzi G., Gaspari F., Fabiola Carrara (180719), Cortinovis M., Mauro Dugo, Flavio Gaspari (180714), Norberto Perico, Fabiola Carrara, Monica Cortinovis (5399138), Villa A., Eleonora Riccio (451487), Sandro Sironi (5512211), Rubis N., Norberto Perico (180737), Perna A., Michele Figuera, Silvia Prandini, Sara Gamba (6560243), Andrea Remuzzi, Sironi S., Antonio Pisani (24903), Anna Caroli, Perico N., Carrara F., Anna Caroli (3905248), Figuera M., Ruggenenti P., Massimo Imbriaco (6560228), Antonio Pisani, Annalisa Perna, Antonio Granata (6560234), Remuzzi A., Annalisa Perna (6560222), Massimo Imbriaco, Michele Figuera (6560237), Caroli A., Granata A., Eleonora Riccio, Morana G., Monica Cortinovis, Giuseppe Remuzzi (180748)   +66 more
core   +1 more source

Systemic Bevacizumab for Severe Bleeding From Acquired Gastrointestinal Vascular Malformations

American Journal of Hematology, Volume 101, Issue 10, Page 2605-2615, October 2026.
Targeted antiangiogenic therapy with systemic bevacizumab for bleeding from acquired GI VMs was found to be safe and effective for chronic and severe bleeding from acquired vascular malformations due to idiopathic angiodysplasia, chronic liver disease, and deficiencies of von Willebrand factor, in a patient population comprised mostly of heavily ...
Nardeen E. Ayad, Jacob R. Anderson, Bimalangshu Dey, Rebecca Karp Leaf, Andrew B. Song, Hanny Al‐Samkari   +5 more
wiley   +1 more source

Octreotide Acetate Long-Acting Formulation Versus Open-Label Subcutaneous Octreotide Acetate in Malignant Carcinoid Syndrome

, 1999
PURPOSE: Subcutaneous (SC) octreotide acetate effectively relieves the diarrhea and flushing associated with carcinoid syndrome but requires long-term multiple injections daily. A microencapsulated long-acting formulation (LAR) of octreotide acetate has
Ronald Bukowski, Jaffer Ajani, Joseph Rubin, William Schirmer, Rodney Pommier, Lowell Anthony, Alan P. Venook, Leonard Saltz, Paresh Dandona   +8 more
core   +1 more source

A transplantable phosphorylation probe for direct assessment of G protein-coupled receptor activation. [PDF]

PLoS ONE, 2012
The newly developed multireceptor somatostatin analogs pasireotide (SOM230), octreotide and somatoprim (DG3173) have primarily been characterized according to their binding profiles.
Andrea Kliewer, Anika Mann, Aline Petrich, Florian Pöll, Stefan Schulz   +4 more
doaj   +1 more source