Ocular Barriers and Their Influence on Gene Therapy Products Delivery [PDF]
Pharmaceutics, 2022 The eye is formed by tissues and cavities that contain liquids whose compositions are highly regulated to ensure their optical properties and their immune and metabolic functions.
Bastien Leclercq +2 more
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Design and synthesis of natural antibacterial derivatives for ocular tuberculosis: a comprehensive review [PDF]
Frontiers in PharmacologyOcular tuberculosis (TB) is an underrecognized extrapulmonary manifestation of Mycobacterium tuberculosis (M. tuberculosis) infection that can result in irreversible vision loss.
Isaiah Osei Duah +12 more
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Emulsion and Emulgel-Based Ophthalmic Drug Delivery Systems [PDF]
PharmaceuticsOphthalmic drug delivery encounters unique challenges due to the anatomical and physiological ocular barriers, necessitating the development of novel drug delivery systems (NDDSs).
Debadatta Mohapatra +2 more
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Prevalence of ocular trauma and barriers to use of personal protective devices among welders in Hetauda, Nepal. [PDF]
PLoS ONEIntroductionWelding poses significant ocular hazards in Nepal's industrial settings; however, data on trauma prevalence and protective barriers remain limited. This study assessed the burden of ocular trauma, personal protective equipment (PPE) practices,
Sunil Thakali +4 more
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Micro/nanoplastics and eye health: a review [PDF]
International Journal of OphthalmologyMicro/nanoplastics (M/NPs) have become pervasive environmental pollutants, posing significant risks to human health through various exposure routes, including ingestion, inhalation, and direct contact.
Lun He +8 more
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Ophthalmology: Navigating ocular barriers with advanced nanocarriers
German Journal of Pharmaceuticals and BiomaterialsThe unique anatomy and physiology of the eye present significant challenges for effective drug delivery, necessitating innovative approaches to manage ocular diseases.
Sanaul Mustafa
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Ocular Drug Delivery Barriers—Role of Nanocarriers in the Treatment of Anterior Segment Ocular Diseases [PDF]
Pharmaceutics, 2018 Ocular drug delivery is challenging due to the presence of anatomical and physiological barriers. These barriers can affect drug entry into the eye following multiple routes of administration (e.g., topical, systemic, and injectable).
Rinda Devi Bachu +4 more
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Nanotechnology-Based Delivery Systems and Retinal Pigment Epithelium: Advances, Targeting Approaches, and Translational Challenges [PDF]
BiomoleculesThe retinal pigment epithelium (RPE) is essential for maintaining retinal integrity, and its dysfunction underlies several progressive ocular diseases, including age-related macular degeneration, choroidal neovascularization (CNV), inherited retinal ...
Michele Nardella +5 more
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ROS-responsive transmembrane peptide-antibody conjugate eyedrops for the non-invasive treatment of choroidoretinopathy [PDF]
Materials Today BioChoroidoretinopathy is a major public health concern that causes significant vision impairment. Although therapeutic antibodies have demonstrated potential in treating these conditions, intravitreal injections remain invasive, associated with adverse ...
Lihang Qu +12 more
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Epithelial barrier dysfunction in ocular allergy [PDF]
Allergy, 2021 AbstractThe epithelial barrier is the first line of defense that forms a protective barrier against pathogens, pollutants, and allergens. Epithelial barrier dysfunction has been recently implicated in the development of allergic diseases such as asthma, atopic dermatitis, food allergy, and rhinitis.
Singh, Neera +3 more
openaire +4 more sources