Ocular drug delivery is challenging due to the presence of anatomical and physiological barriers. These barriers can affect drug entry into the eye following multiple routes of administration (e.g., topical, systemic, and injectable).
Rinda Devi Bachu +4 more
doaj +2 more sources
Drug Delivery Challenges and Current Progress in Nanocarrier-Based Ocular Therapeutic System
Drug instillation via a topical route is preferred since it is desirable and convenient due to the noninvasive and easy drug access to different segments of the eye for the treatment of ocular ailments.
Md Habban Akhter +9 more
doaj +1 more source
A Review on Conventional and Novel Topical Ocular Drug Delivery System
Ocular drug delivery is a very challenging area for ophthalmologists and drug delivery scientists due to the structural and barrier complexity of the eye.
Mohamad Faeznudin Rozi +1 more
doaj +1 more source
Epidemiological study of ocular trauma in an urban slum population in Delhi, India. [PDF]
PURPOSE: To study the epidemiology and clinical profile of victims of ocular trauma in an urban slum population. MATERIALS AND METHODS: This cross-sectional study, conducted on 500 families each in three randomly selected urban slums in Delhi, collected ...
Vats, S +5 more
core +1 more source
Recent Developments of Nanostructures for the Ocular Delivery of Natural Compounds
Ocular disorders comprising various diseases of the anterior and posterior segments are considered as the main reasons for blindness. Natural products have been identified as potential treatments for ocular diseases due to their anti-oxidative ...
Malihe Sadat Razavi +7 more
doaj +1 more source
Application of Convergent Science and Technology toward Ocular Disease Treatment
Eyes are one of the main critical organs of the body that provide our brain with the most information about the surrounding environment. Disturbance in the activity of this informational organ, resulting from different ocular diseases, could affect the ...
Ayça Bal-Öztürk +7 more
doaj +1 more source
Ocular disorders in children with learning disabilities in special education schools of Pune, India. [PDF]
AIM: The aim was to study and treat ocular disorders in children with learning disabilities (cLDs) and explore associations with their perinatal history.
Gilbert, Clare +12 more
core +1 more source
Immunological studies of chronic ocular toxoplasmosis : up-regulation of major histocompatibility complex class I and transforming growth factor beta and a protective role for interleukin-6 [PDF]
A murine model was used to characterize the local immune and inflammatory response during ocular toxoplasmosis. Major histocompatibility complex (MHC) class I, normally expressed at low levels in immune-privileged sites such as the eye, was up-regulated ...
Byrne, N. +6 more
core +4 more sources
Nanotechnology-based ocular drug delivery systems: recent advances and future prospects
Ocular drug delivery has constantly challenged ophthalmologists and drug delivery scientists due to various anatomical and physiological barriers. Static and dynamic ocular barriers prevent the entry of exogenous substances and impede therapeutic agents'
Shiding Li, Liangbo Chen, Yao Fu
doaj +1 more source
There are two main blood-ocular barriers, the blood-aqueous barrier and the blood-retinal barrier. The blood-aqueous barrier is formed by the nonpigmented ciliary epithelium of the ciliary body and the vascular endothelium of the iris vessels.
Hou, Ping-Kang +3 more
core +1 more source

