Results 11 to 20 of about 49,463 (304)
Lipid-Based Nanocarriers as Topical Drug Delivery Systems for Intraocular Diseases
Pharmaceutics, 2021 Effective drug delivery to intraocular tissues remains a great challenge due to complex anatomical and physiological barriers that selectively limit the entry of drugs into the eye.
Jose Navarro-Partida +5 more
doaj +1 more source
Nanomedicine for Treating Diabetic Retinopathy Vascular Degeneration
International Journal of Translational Medicine, 2021 The incidence of diabetes and the pathological conditions associated with chronic hyperglycemia is increasing worldwide. Among them, diabetic retinopathy represents a leading cause of vision loss, causing a significant structural and functional ...
Tatiana Borodina +3 more
doaj +1 more source
Topical Drug Delivery to the Posterior Segment of the Eye
Pharmaceutics, 2022 Topical drug delivery to the posterior segment of the eye is a very complex challenge. However, topical delivery is highly desired, to achieve an easy-to-use treatment option for retinal diseases. In this review, we focus on the drug characteristics that
Marina Löscher +3 more
doaj +1 more source
Ultrasound-Mediated Ocular Drug Delivery: From Physics and Instrumentation to Future Directions
Micromachines, 2023 Drug delivery to the anterior and posterior segments of the eye is impeded by anatomical and physiological barriers. Increasingly, the bioeffects produced by ultrasound are being proven effective for mitigating the impact of these barriers on ocular drug
Blair Duncan +4 more
doaj +1 more source
Lipid Nanoparticles for the Posterior Eye Segment
Pharmaceutics, 2021 This review highlights the application of lipid nanoparticles (Solid Lipid Nanoparticles, Nanostructured Lipid Carriers, or Lipid Drug Conjugates) as effective drug carriers for pathologies affecting the posterior ocular segment. Eye anatomy and the most
Lorena Bonilla +8 more
doaj +1 more source
Pharmaceutics, 2023 The eye’s intricate anatomical barriers pose significant challenges to the penetration, residence time, and bioavailability of topically applied medications, particularly in managing uveitis and neuro-ophthalmologic conditions.
Kevin Y. Wu +4 more
doaj +1 more source
Advancement in Ocular Drug Delivery System to Overcome Ocular Barrier
International Journal of Pharmaceutical Sciences Review and Research, 2021 The Ocular drug delivery system (ODDS) is the prominently challenging system faced by pharmaceutical researchers. Ophthalmic preparations are available in buffered, sterile and isotonic solutions. For the ocular delivery of drugs, various types of dosage forms are prepared and dispensed.
Supriya Nikam +3 more
openaire +1 more source
Drug Delivery Challenges and Current Progress in Nanocarrier-Based Ocular Therapeutic System
Gels, 2022 Drug instillation via a topical route is preferred since it is desirable and convenient due to the noninvasive and easy drug access to different segments of the eye for the treatment of ocular ailments.
Md Habban Akhter +9 more
doaj +1 more source
Ocular Surface as Barrier of Innate Immunity [PDF]
The Open Ophthalmology Journal, 2015 Sight is one of the most important senses that human beings possess. The ocular system is a complex structure equipped with mechanisms that prevent or limit damage caused by physical, chemical, infectious and environmental factors. These mechanisms include a series of anatomical, cellular and humoral factors that have been a matter of study. The cornea
Bolaños-Jiménez, Rodrigo +6 more
openaire +2 more sources
Why do people not attend for treatment for trachomatous trichiasis in Ethiopia? A study of barriers to surgery. [PDF]
, 2012 BACKGROUND: Trachomatous trichiasis (TT) surgery is provided free or subsidised in most trachoma endemic settings. However, only 18-66% of TT patients attend for surgery.
Bedri, Amir +8 more
core +6 more sources