Self-induced Elizabethkingia meningoseptica endophthalmitis: a case report [PDF]
INTRODUCTION: Endophthalmitis is a sight-threatening condition defined as any inflammation of the internal ocular spaces. It is classified as either endogenous or exogenous depending on the route of infection.
Paul P Connell +4 more
core +2 more sources
Soluble Epoxide Hydrolase Inhibition for Ocular Diseases: Vision for the Future [PDF]
Ocular diseases cause visual impairment and blindness, imposing a devastating impact on quality of life and a substantial societal economic burden. Many such diseases lack universally effective pharmacotherapies.
Corson, Timothy W., Park, Bomina
core +1 more source
Subconjunctival delivery of p75NTR antagonists reduces the inflammatory, vascular, and neurodegenerative pathologies of diabetic retinopathy [PDF]
The p75NTR is a novel therapeutic target validated in a streptozotocin mouse model of diabetic retinopathy. Intravitreal (IVT) injection of small molecule p75NTR antagonist THX-B was therapeutic and resolved the inflammatory, vascular, and ...
Barcelona, Pablo Federico +5 more
core +1 more source
Breakdown of the Blood-Ocular Barrier as a Strategy for the Systemic Use of Nanosystems
Several drug delivery systems have been proposed to overcome physiological barriers, improving ocular bioavailability. Systemic routes are seldom used due to the blood-ocular barrier.
Vital P. Costa +3 more
doaj +1 more source
Current Knowledge and Attitudes Concerning Cost-Effectiveness in Glaucoma Pharmacotherapy: A Glaucoma Specialists Focus Group Study. [PDF]
Background:Rising healthcare costs motivate continued cost-reduction efforts. To help lower costs associated with open-angle glaucoma (OAG), a prevalent, progressive disease with substantial direct and indirect costs, clinicians need to understand the ...
Cioffi, George A +4 more
core
Ophthalmic Drug Delivery Systems for Antibiotherapy—A Review
The last fifty years, ophthalmic drug delivery research has made much progress, challenging scientists about the advantages and limitations of this drug delivery approach.
Marion Dubald +3 more
doaj +1 more source
Prevalence of disorders recorded in Cavalier King Charles Spaniels attending primary-care veterinary practices in England [PDF]
Concerns have been raised over breed-related health issues in purebred dogs, but reliable prevalence estimates for disorders within specific breeds are sparse.
Brodbelt, D C +5 more
core +3 more sources
Phylogenetic analysis of the Camaenidae (Mollusca: Stylommatophora) with special emphasis on the american taxa [PDF]
The monophyly of the land snail family Camaenidae has been in doubt due to a disjunct bihemispheric distributional pattern and to the lack of morphological synapomorphies.
Cuezzo, Maria Gabriela
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Nanoparticles in the ocular drug delivery
Ocular drug transport barriers pose a challenge for drug delivery comprising the ocular surface epithelium, the tear film and internal barriers of the blood-aqueous and blood-retina barriers.
Wen-Song Zhang +4 more
doaj +1 more source
A new species, Lasioglossum (Eickwortia) hienae, from Mexico (Apoidea: Halictidae) [PDF]
A new species from Colima, Mexico, Lasioglossum (Eickwortia) hienae Gibbs & Dumesh, new species, is described and illustrated. Lasioglossum hienae is distinguished from related species based on a combination of morphological, geographical, and ...
Dumesh, Sheila, Gibbs, Jason
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