Results 1 to 10 of about 266,707 (341)

Establishment of a nomogram model to predict malignant risk in patients with ocular surface squamous neoplasia and ocular surface squamous epithelial tumors [PDF]

Frontiers in Oncology
ObjectiveTo develop and internally validate a nomogram to predict the probability that a clinically suspected ocular surface squamous epithelial tumor is histopathologically malignant.MethodsThis retrospective study included 92 patients with ocular ...
Xie Fang, Xie Fang, Xie Fang, Xie Fang, Xie Fang, Xie Fang, Zhiwen Xie, Zhiwen Xie, Zhiwen Xie, Zhiwen Xie, Zhiwen Xie, Zhiwen Xie, Yuan Lin, Yuan Lin, Yuan Lin, Yuan Lin, Yuan Lin, Yuan Lin, Miaomiao Liu, Miaomiao Liu, Miaomiao Liu, Miaomiao Liu, Miaomiao Liu, Miaomiao Liu, Hanqiao Li, Hanqiao Li, Hanqiao Li, Hanqiao Li, Hanqiao Li, Hanqiao Li, Shunrong Luo, Shunrong Luo, Shunrong Luo, Shunrong Luo, Shunrong Luo, Shunrong Luo, Xianwen Xiao, Xianwen Xiao, Xianwen Xiao, Xianwen Xiao, Xianwen Xiao, Xianwen Xiao, Shangkun Ou, Shangkun Ou, Shangkun Ou, Shangkun Ou, Shangkun Ou, Shangkun Ou, Huping Wu, Huping Wu, Huping Wu, Huping Wu, Huping Wu, Huping Wu   +53 more
doaj   +2 more sources

Safety and Efficacy of Corneal Cross-Linking in Patients Affected by Keratoconus: Long-Term Results

Medical Sciences, 2023
The present study evaluated the effectiveness and safety of corneal collagen cross-linking (CXL). A total of 886 eyes with progressive keratoconus were enrolled in a retrospective cohort study in a tertiary care university hospital.
Karl Anders Knutsson, Paola Noemi Genovese, Giorgio Paganoni, Oriella Ambrosio, Giulio Ferrari, Arianna Zennato, Michela Caccia, Madeleine Cataldo, Paolo Rama   +8 more
doaj   +1 more source

Possible Strategies to Mitigate Placebo or Vehicle Response in Dry Eye Disease Trials: A Narrative Review

Ophthalmology and Therapy, 2023
Many candidate drugs for dry eye disease (DED) have been assessed over the years in pursuit of demonstrating efficacy in both signs and symptoms. However, patients with DED have very limited treatment options for management of both signs and symptoms of ...
Michela Montecchi-Palmer, Min Wu, Maurizio Rolando, Charis Lau, Victor L. Perez Quinones, Reza Dana   +5 more
doaj   +1 more source

Ocular surface tumors

Oman Journal of Ophthalmology, 2009
Tumors of the conjunctiva and cornea comprise a large and varied spectrum of conditions. These tumors are grouped into two major categories of congenital and acquired lesions. The acquired lesions are further subdivided based on origin of the mass into surface epithelial, mucoepidermoid, melanocytic, vascular, fibrous, neural, histiocytic, myxoid ...
Meghana Anika Varde, Jyotirmay Biswas
openaire   +6 more sources

Topical fosaprepitant for the treatment of ocular pain and inflammation

American Journal of Ophthalmology Case Reports, 2023
Purpose: To assess whether topical administration of fosaprepitant improves intractable chronic ocular pain and inflammation. Methods: We report three clinical cases of female patients with drug-resistant ocular pain associated with inflammatory diseases
Giuseppe Suanno, Matteo Pederzolli, Romina Mayra Lasagni Vitar, Philippe Fonteyne, Giulio Ferrari   +4 more
doaj   +1 more source

IL-17 Producing Lymphocytes Cause Dry Eye and Corneal Disease With Aging in RXRα Mutant Mouse

Frontiers in Medicine, 2022
PurposeTo investigate IL-17 related mechanisms for developing dry eye disease in the Pinkie mouse strain with a loss of function RXRα mutation.MethodsMeasures of dry eye disease were assessed in the cornea and conjunctiva.
Jehan Alam, Ghasem Yazdanpanah, Rinki Ratnapriya, Nicholas Borcherding, Cintia S. de Paiva, DeQuan Li, Rodrigo Guimaraes de Souza, Rodrigo Guimaraes de Souza, Zhiyuan Yu, Stephen C. Pflugfelder   +9 more
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Advances in clinical examination of lacrimal gland

Frontiers in Medicine, 2023
In humans, the lacrimal gland is located in the socket of the frontal bone above the outer orbital area. As an essential part of the eye surface, the gland is fixed to the orbital periosteum by connective tissue.
Yuan Lin, Yuan Lin, Yuan Lin, Yuan Lin, Yujie Zhang, Yujie Zhang, Yujie Zhang, Yujie Zhang, Ke Shi, Ke Shi, Ke Shi, Ke Shi, Huping Wu, Huping Wu, Huping Wu, Huping Wu, Shangkun Ou, Shangkun Ou, Shangkun Ou, Shangkun Ou, Shangkun Ou   +20 more
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Assessing the ocular surface microbiome in severe ocular surface diseases [PDF]

The Ocular Surface, 2020
There is growing evidence for a critical role of the microbiome in ocular health and disease. We performed a prospective, observational study to characterize the ocular surface microbiome (OSM) in four chronic ocular surface diseases (OSDs) and healthy controls.Sterile swabs were used to collect samples from each eye of 39 patients (78 eyes).
Michael J. Zilliox, William S. Gange, Gina Kuffel, Carine R. Mores, Cara Joyce, Paul de Bustros, Charles S. Bouchard   +6 more
openaire   +2 more sources

Advanced Therapy Medicinal Products for Eye Diseases: Goals and Challenges

Pharmaceutics, 2021
Advanced therapy medicinal products (ATMPs) are a novel class of medicines with enormous potential to improve treatments for a wide range of diseases, including those affecting eye structures [...]
Yolanda Diebold, Laura García-Posadas
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Is the Conjunctiva a Potential Target for Advanced Therapy Medicinal Products?

Pharmaceutics, 2021
The conjunctiva is a complex ocular tissue that provides mechanical, sensory, and immune protection for the ocular surface. It is affected by many diseases through different pathological mechanisms.
Yolanda Diebold, Laura García-Posadas
doaj   +1 more source